Selective Inhibitors of Janus Kinase 3 Modify Responses to Lipopolysaccharides by Increasing the Interleukin-10-to-Tumor Necrosis Factor α Ratio by Julian Laux (13047767)

“…., tofacitinib, 0.2–0.4 μmol/kg bid) in clinical use, suggesting an efficient underlying mode of action. We hypothesized that their effectiveness is due to their ability to raise the ratio of IL-10 to TNFα. …”

PfSUB2PD Inhibits MESH in a Selective, Dose-Dependent Manner by Philippa K Harris (27615)

“…<div><p>(A) Shedding of AMA1 and MSP1 from isolated merozoites was assayed in the presence of the indicated additives. Two different batches (1 and 2) of purified PfSUB2PD were tested, in each case alongside a similar dilution of the membrane flow-through (Conc FT) from the final step of concentration by ultrafiltration. …”

AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes by Mako Yasuda-Yamahara (5509151)

Inhibition of mineralization by phosphorylated MEPE-ASARM peptide in a 3D collagen/tooth slice culture model. A: by Benjamin Salmon (381317)

Transforming Small-Molecule Nanoaggregation into Functional Drug Delivery Platforms by JunHyuk Kim (21235657)

“…The IC₅₀ value of <b>Nano-CC1-Acl</b> further decreases to 0.20 ± 0.16 μM in the presence of cysteine, a biothiol. …”

Transforming Small-Molecule Nanoaggregation into Functional Drug Delivery Platforms by JunHyuk Kim (21235657)

“…The IC₅₀ value of <b>Nano-CC1-Acl</b> further decreases to 0.20 ± 0.16 μM in the presence of cysteine, a biothiol. …”

Discontinuously Dewetting Solvent Arrays: Droplet Formation and Poly-Synchronous Surface Extraction for Mass Spectrometry Imaging Applications by Rory A. H. McEwen (12525466)

Discontinuously Dewetting Solvent Arrays: Droplet Formation and Poly-Synchronous Surface Extraction for Mass Spectrometry Imaging Applications by Rory A. H. McEwen (12525466)

Effects of Common Polymorphisms rs11614913 in <em>miR-196a2</em> and rs2910164 in <em>miR-146a</em> on Cancer Susceptibility: A Meta-Analysis by Wei Xu (28953)

“…Rs11614913 in <em>miR-196a2</em> and rs2910164 in <em>miR-146a</em> are shown to associate with increased/decreased cancer risk. …”

MiR-29a targets PTEN. by Guangyao Kong (185282)

“…Empty pcDNA3.0 plasmid (200 ng) was used as a negative control. (C) Luciferase reporter gene assay showed that the decreased luciferase activities of PTEN 3′UTR reporter (PTEN 3′UTR-1 or PTEN 3′UTR-2) in HepG2 cells mediated by miR-29a overexpression (200 ng) was rescued by a miR-29a inhibitor in a dose dependent manner (30, 50, and 100 nM). …”

Modulation of Aβ-induced deleterious signaling. by Tao Yang (184280)

“…<p>For each study, LM11A-24 and -31 were present at 100 nM and NGF at 50 or 100 ng/ml. …”

Response to square wave CO₂ stimulus – CVR and DFA maps. by W. Alan C. Mutch (122579)

“…The percentage of ‘blue’ DFA voxels noticeably decreased over time. The step change in end-tidal CO₂ is 8 mmHg.…”

Effects of sialidase treatment on substantia nigra dopamine neurons. by Jay S. Schneider (671374)

“…<p>Sub-acute MPTP treatment (aCSF-MPTP) resulted in significant decreases in the number of tyrosine hydroxylase immunopositive (A.) and Nissl-stained (B.) cells in the substantia nigra pars compacta. …”

Data selection by changes in the firing rate. by Huu Hoang (9188747)

“…<p>A: the histograms of firing rate change by drug treatments (decreased by CBX and increased by PIX) compared to the CON condition. …”

Identity between upstream stripes and Alu-sequences and their expression as a function of upstream poly(A)-segments of the GA-sequences. by Guenter Albrecht-Buehler (266704)

“…<p>The GPxIs show portions of the GA-complexes of human chr.1 after sorting them by the decreasing size of poly(A)-segments at the upstream end of the GA-sequences. …”

CORT triggered a slow-onset increase in GluN2A/GluN2B ratio. by Yiu Chung Tse (340737)

“…<p>(<b>A</b>) Plots of NMDAR-EPSC amplitude from control and CORT-treated slices against time show decreased EPSC amplitude after sequential application of Ro (1 µM; for 30 min) and a mixture of Ro and a subunit non-selective NMDAR antagonist APV (50 µM; for 10 min). …”

A process for CO2 capture and brine salinity reduction through reaction with potassium hydroxide: A multi-stage evaluation by Mourad, Aya A-H.

“…In the third method, the recovery of Ca2+ and Mg2+ was approximately 76.3% and 94.6%, respectively, following the pre-treatment step (filtration), followed by the same stages as in the second method. …”
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Image_2_Biochemical basis for the formation of organ-specific volatile blends in mint.pdf by B. Markus Lange (2048524)

Table_4_Regulatory Role of Hexokinase 2 in Modulating Head and Neck Tumorigenesis.xlsx by Wan-Chun Li (450324)

“…Loss of HK2 in HNSCC cells resulted in reduced cell (in vitro) and tumor (in vivo) growth, as well as decreased epithelial-mesenchymal transition–mediated cell movement; in contrast, HK2-deficient HNSCC cells exhibited greater sensitivity to chemotherapeutic drugs cisplatin and 5-fluorouracil but are more resistant to photodynamic therapy, indicating that HK2 expression could selectively define treatment sensitivity in HNSCC cells. …”

Synthesis and Activity of Ruthenium Olefin Metathesis Catalysts Coordinated with Thiazol-2-ylidene Ligands by Georgios C. Vougioukalakis (2290621)

“…A new family of ruthenium-based olefin metathesis catalysts bearing a series of thiazole-2-ylidene ligands has been prepared. These complexes are readily accessible in one step from commercially available (PCy₃)₂Cl₂RuCHPh or (PCy₃)Cl₂RuCH(<i>o</i>-<i>i</i>PrO−Ph) and have been fully characterized. …”