S1 Graphical abstract - by Shadi Nazarizadeh (20108029)

“…This study focuses on examining the effects of dimethyl itaconate (DMI) on cognition, motor coordination, and anxiety-like behavior in male rats that have experienced HINS. 42 male Wistar newborn rats (PND10) were randomly divided into six groups (n = 7). 1) Control (Vehicle only); received DMI solvent (0.1ml) without applying hypoxia. 2–3) DMI; receiving (20 and 50 mg/kg; i.p). 4) HINS; they were placed in a hypoxia chamber with 7% oxygen and 93% nitrogen concentration for 15 minutes. 5–6) DMI+HINS; received DMI (20 and 50 mg/kg; i.p) 24h before hypoxia. …”

Metabolic labelling of <i>P</i>. <i>falciparum</i> glycolipids with GDP-[^<i>3</i>H]-mannose. by Michaela S. Bulloch (19557058)

The TGF-β1/Smads signaling pathway and α-SMA expression levels in mice. by Lu Lin (201289)

Image_2_Differential responses of canonical nitrifiers and comammox Nitrospira to long-term fertilization in an Alfisol of Northeast China.PDF by Yanan Wang (123548)

“…<p>The newly identified complete ammonia oxidizer (comammox) that converts ammonia directly into nitrate has redefined the long-held paradigm of two-step nitrification mediated by two distinct groups of nitrifiers. …”

EZH2 knockdown causes a significant reduction in SCLC cell viability. by Bradley P. Coe (102517)

“…(<b>C,D,G,H</b>) To assess the viability of <i>EZH2</i> knockdown relative to controls cells we performed MTT assays. Knockdown of EZH2 caused a significant and reproducible decrease in cell viability in both SCLC cell lines (Student's t-test, p<0.05).…”

Sox2 direct interaction with mouse <i>Huwe1</i> and human <i>Huwe1</i> genes. by Yen-Fu Cheng (5819855)

Dietary Patterns Associated with Breast Cancer in the Middle East: A Scoping Review by Zamzam, Syed

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Table 1_Case Report: Identification of a novel hemizygous CFAP47 variant in a primary ciliary dyskinesia patient with dual ciliary and flagellar defects.docx by Miao He (148269)

“…</p>Methods<p>We investigated a male patient with suspected PCD who exhibited “9 + 2” ultrastructural abnormalities in both bronchial cilia and sperm flagella. …”

The knockdown efficacy of a range of concentrations of siRab41(4). by Shijie Liu (442365)

“…Error bars in (A) represent the mean ± SEM of three replicates. …”

Preconceptional Folate Supplementation and the Risk of Spontaneous Preterm Birth: A Cohort Study by Radek Bukowski (63008)

“…Comparing to no supplementation, preconceptional folate supplementation for 1 y or longer was associated with a 70% decrease in the risk of spontaneous preterm delivery between 20 and 28 wk (41 [0.27%] versus 4 [0.04%] spontaneous preterm births, respectively; HR 0.22, 95% confidence interval [CI] 0.08–0.61, <em>p</em> = 0.004) and a 50% decrease in the risk of spontaneous preterm delivery between 28 and 32 wk (58 [0.38%] versus 12 [0.18%] preterm birth, respectively; HR 0.45, 95% CI 0.24–0.83, <em>p</em> = 0.010). …”

Presynaptic marker CtBP2 counts of the IHCs and OHCs. by Pezhman Salehi (4528993)

“…CtBP2 counts of the IHCs showed two cochlea out of five with nearly 50% decreased numbers of the puncta when compared to WT controls; however, the average of the counts (five cochlea) did not show a statistically significant difference (D). …”

Data_Sheet_1_Hexokinase 2 Depletion Confers Sensitization to Metformin and Inhibits Glycolysis in Lung Squamous Cell Carcinoma.PDF by Wenzheng Guo (8380134)

“…Compared with lung adenocarcinoma (ADCs), lung SCCs reportedly utilized higher levels of glucose metabolism to meet the anabolic and catabolic needs required to sustain rapid tumor growth. Hexokinase 2 (HK2) is an enzyme that catalyzes the rate-limit and first committed step in glucose metabolism. …”

Data_Sheet_2_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”

Percentage survival at 0 h, 2.5 h in oxidative stress assay and percentage survival in thermal resistance assay. by Manoj Limbraj Yellurkar (11467219)

Effects of a mitochondrial–nuclear interaction on adult fecundity and sensory structures. by Colin D. Meiklejohn (209549)

“…<p>(A) The <i>simw⁵⁰¹</i> mtDNA decreases the total number of eggs females laid by 50% only in the <i>OreR</i> nuclear background (mtDNA×nuclear interaction: <i>F</i> = 9.772, <i>P</i> = 0.004, <i>N</i> = 6–11 females per genotype). …”

Patient participation in the development of a clinical guideline for inherited retinal dystrophies by P. Serrano-Aguilar (2737951)

Data_Sheet_1_Empowering a Methanol-Dependent Escherichia coli via Adaptive Evolution Using a High-Throughput Microbial Microdroplet Culture System.xlsx by Jia Wang (51945)

“…Given the automatic high-throughput selection of the MMC, a three-stage regime of an adaptive evolution experiment via gradually decreasing the availability of gluconate during the cultivation was performed for 50 days continuously in order to obtain the mutations. …”

Unsafe abortion in Brazil: a systematic review of the scientific production, 2008-2018 by Rosa Maria Soares Madeira Domingues (2795005)

“…We evaluated 50 articles. The prevalence of induced abortion in Brazil was estimated by a direct method to be 15% in 2010 and 13% in 2016. …”

A cGMP signaling contributes to the Tav response in the AFD neurons. by Shu Liu (160219)

“…<p>(A) The head Tav responses of mutants in CNG channel genes are shown. …”

Mitochondrial injury is a key mechanism to induce histones-mediated apoptosis in lymphocytes. by Zhan-Guo Liu (475213)

“…Inhibition of mitochondrial permeability transition by CSA (25 and 50 ng/ml) can decrease the peripheral lymphocyte apoptosis. alues are presented as means ± SD (n = 3). ▾ P<0.05, as compared with CSA 0 ng/ml His 50 µg/ml group.…”