Image 2_Phage (cocktail)-antibiotic synergism: a new frontier in addressing Klebsiella pneumoniae resistance.tif by Chandrasekar Karthika (21255878)

“…Evaluation of phages as a cocktail demonstrated a substantial improvement in lytic ability, achieving complete (100%) lysis (at MOI 1) of clinical isolates compared to individual phages, achieving 50 and 25% lysis at MOI 1. …”

Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage - Fig 3 by Lucia Reh (546554)

Protein and mRNA noise are inversely correlated with abundance. by Roy D. Dar (816541)

Inhibition of <i>in vitro</i> and <i>in vivo</i> inflammatory responses in rats by p30A peptide. by Jérôme Rambert (46851)

“…(D) Histopathologic analysis confirm p30A ability to decrease all components of AIA lesions: pannus formation and inflammation of the synovium (P), deformity of joint and bones (asterix), bone remodeling and destruction (arrowhead), bone neoformation (arrows) and cartilage destruction.…”

Generation of CYP5122A1 half knock-outs. by Smriti Verma (204089)

“…<b>D:</b> Western blot analysis of cell lysates from WT and HKO parasites probed with anti-CYP5122A1 antibody showing decreased level of CYP5122A1 protein in the HKO parasites. …”

PD-1-deficient CD45.2⁺ Tregs are more competitive than WT CD45.2⁺ Tregs in suppressing CD45.1⁺ conventional CD4 T cells following TCR stimulation <... by Liaoxun Lu (179293)

Trichopsistides A and B: Two Highly Oxygenated Pentacyclic Polyketides with Promising Inhibitory Effects on the NF-κB Signaling Pathway from the Fungus <i>Trichoderma koningiopsis<... by Li Feng (77923)

“…Two highly oxygenated pentacyclic polyketides with two new carbon skeletons, trichopsistide A (<b>1</b>) and trichopsistide B (<b>2</b>), were isolated from the plant endophyte <i>Trichoderma koningiopsis</i> WZ-196 derived from the leaf of <i>Rubia podantha</i> Diels. …”

ceRNA network. by Yalan Yang (735975)

Effects of Cyr61 and Wnt5a on regenerating vasculature and musculature. by Devon C. Snow-Lisy (798898)

“…Scale bar, 50 μm. (Unseeded, MSC and MSC/CD34⁺ HSPC images shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0138643#pone.0138643.s001" target="_blank">S1 Fig</a>).…”

Table_1_Guanidine acetic acid exhibited greater growth performance in younger (13–30 kg) than in older (30–50 kg) lambs under high-concentrate feedlotting pattern.docx by Wen-Juan Li (1444948)

“…In a brief, the results obtained in the present study suggested that GAA (UGAA and CGAA; 1 g/kg DM) could be applied to improve growth performance in younger (13–30 kg) instead of older (30–50 kg) lambs in high-concentrate feedlotting practice.…”

Discovery of PMSA Derivative <b>11</b> as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis <i>In Vitro</i> and <i>In Vivo</i> by Zhihao Chen (513264)

“…Additionally, <b>11</b> blocked the formation of F-action belts and bone resorption in a concentration-dependent manner. Mechanistically, <b>11</b> decreased the expression of genes required for osteoclastogenesis by blocking NFATc1 translocation from the cytoplasm to nucleus. …”

Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”

Dietary or gavaged TU-100 and the ginger component decrease enteropooling stimulated by anti-CD3 antibody treatment in specified pathogen free (SPF) and germ free (GF) C57Bl6 mice. by Nobuhiro Ueno (346397)

Knockdown of CRT suppressed VEGF-A expression and mRNA stability through ARE in AGS cells. by Po-Chu Lee (438366)

“…VEGF-A mRNA was significantly less stable in the CRT-knockdown cells with lower half-life and 50% mRNA remaining time. …”

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 by Marta E. Capala (652765)

“…Downregulation of SAM50 also impaired the proliferation and replating capacity of BCR-ABL-expressing cells, again associated with a decreased mitochondrial membrane potential. …”

Effects of ROCK inhibitors H-1152 and Y-27632 on TNF-induced MLC phosphorylation, actin and CL5 reorganization and the fall in TEER. by Paul R. Clark (714064)

Analysis of Research Activity in Gastroenterology: Pancreatitis Is in Real Danger - Fig 2 by Andrea Szentesi (3239193)

Analysis of requirement for MYPT1 expression in TNF-induced MLC phosphorylation and leak. by Paul R. Clark (714064)

Printed Silver Nanowire-PEDOT:PSS Composite Electrodes for Flexible Transparent Microsupercapacitor Applications by Neha Sharma (433468)

“…Typically, the fabrication of such composite electrodes for supercapacitors (SCs) is a multistep process requiring electro/in situ polymerization, whereas in this work, a simple two-step direct ink writing is adopted. An ink made of Ag NWs and PEDOT:PSS is used to print the electrodes in an interdigitated design. …”

Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles <i>in vitro</i> - Fig 4 by Remo Campiche (3714208)

“…Hair follicles treated with lower concentrations of Gambogic Amide kept their anagen-like appearance. Bars = 50 μm. <b>E: Immunohistochemical quantification of melanocytes with p16, a marker for mature and senescent melanocytes</b>. …”