Showing 6,781 - 6,800 results of 30,319 for search '(( 2 step decrease ) OR ( 50 ((((we decrease) OR (nn decrease))) OR (a decrease)) ))', query time: 0.60s Refine Results
  1. 6781
  2. 6782

    Neurally mediated syncope diagnosis based on adenylate cyclase activity in Japanese patients - Fig 3 by Tomoyoshi Komiyama (474366)

    Published 2019
    “…B: Isoproterenol was decreased by 5 mM for each 1/10 at the following concentrations: 5 nM, 50 nM, 500 nM, 5 μM, 50 μM, 500 μM, and 5 mM. …”
  3. 6783
  4. 6784
  5. 6785
  6. 6786
  7. 6787
  8. 6788

    The Design, Synthesis, and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile by Shiv K. Sharma (1945762)

    Published 2018
    “…To circumvent this problem, a series of cholic acid amides were synthesized and tested against R20291. …”
  9. 6789
  10. 6790

    Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

    Published 2021
    “…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC<sub>50</sub> < 200 nM). …”
  11. 6791

    Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

    Published 2021
    “…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC<sub>50</sub> < 200 nM). …”
  12. 6792

    Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

    Published 2021
    “…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC<sub>50</sub> < 200 nM). …”
  13. 6793

    Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

    Published 2021
    “…Concomitant inhibition of key epigenetic pathways involved in silencing tumor suppressor genes has been recognized as a promising strategy for cancer therapy. Herein, we report a first-in-class series of quinoline-based analogues that simultaneously inhibit histone deacetylases (from a low nanomolar range) and DNA methyltransferase-1 (from a mid-nanomolar range, IC<sub>50</sub> < 200 nM). …”
  14. 6794
  15. 6795
  16. 6796
  17. 6797
  18. 6798

    DN dynamin II (K44A) slows down endocytosis of KCa2.3. by Yajuan Gao (309862)

    Published 2013
    “…<p><b>A.</b> BLAP-KCa2.3 was co-expressed with either WT or K44A dynamin II and cell surface expression of the channel evaluated in triplicate as detailed in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0044150#s2" target="_blank">Methods</a> (top panel). …”
  19. 6799
  20. 6800