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8261
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8262
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8263
Hybrid Molecules of Benzothiazole and Hydroxamic Acid as Dual-Acting Biofilm Inhibitors with Antibacterial Synergistic Effect against Pseudomonas aeruginosa Infections
Published 2025“…This study synthesized benzothiazole-conjugated hydroxamic acid derivatives as dual-acting biofilm inhibitors, and compound <b>JH21</b> was identified as the hit compound with potent submicromolar biofilm inhibitory activity (IC<sub>50</sub> = 0.4 μM). Further mechanistic studies demonstrated not only that the production of virulence was decreased through mainly inhibiting QS system but also that <b>JH21</b> competed for iron with the high-affinity siderophore pyoverdine, inducing iron deficiency and inhibiting biofilm. …”
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8264
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8265
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8266
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8267
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8268
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8269
Meta-analyses of the association of <i>G6PC2</i> allele variants with elevated fasting glucose and type 2 diabetes
Published 2017“…Per increment of G allele at rs560887 and A allele at rs573225 resulted in a FG 0.070 mmol/l and 0.075 mmol/l higher (ß (95% CI) = 0.070 (0.060, 0.079), <i>p</i> = 4.635e-50 and 0.075 (0.065, 0.085), <i>p</i> = 5.856e-48, respectively). …”
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8270
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8271
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8272
Table_1_Immunotherapy With Recombinant Alt a 1 Suppresses Allergic Asthma and Influences T Follicular Cells and Regulatory B Cells in Mice.docx
Published 2021“…</p>Methods<p>We synthesized and purified rAlt a 1. Alternaria-sensitized and challenged mice received subcutaneous immunotherapy (SCIT) with four different rAlt a 1 dosages (5, 50, 100, and 150 µg) or PBS only. …”
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8273
Image_1_Immunotherapy With Recombinant Alt a 1 Suppresses Allergic Asthma and Influences T Follicular Cells and Regulatory B Cells in Mice.tif
Published 2021“…</p>Methods<p>We synthesized and purified rAlt a 1. Alternaria-sensitized and challenged mice received subcutaneous immunotherapy (SCIT) with four different rAlt a 1 dosages (5, 50, 100, and 150 µg) or PBS only. …”
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8274
Image_2_Immunotherapy With Recombinant Alt a 1 Suppresses Allergic Asthma and Influences T Follicular Cells and Regulatory B Cells in Mice.tif
Published 2021“…</p>Methods<p>We synthesized and purified rAlt a 1. Alternaria-sensitized and challenged mice received subcutaneous immunotherapy (SCIT) with four different rAlt a 1 dosages (5, 50, 100, and 150 µg) or PBS only. …”
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8275
GFP+ NPC Implant Apoptosis. Implants were sectioned and immunostained for the early effector caspase, cleaved caspase-3 (red, GFP = green, DAPI = blue) and area of fluorescence rel...
Published 2013“…<p>This initially higher rate of apoptosis significantly decreased by day 5 (0.036±0.050, p = 0.0063) to a rate comparable to that of the NPC∶BEC implants. …”
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8276
<i>In silico</i> screening identifies doxazosin as a novel agonist for EphA2 receptor.
Published 2012“…Note decreasing amount of EphA2 following ephrin-A1 and doxazosin treatment. …”
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8277
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8278
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8279
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8280
DataSheet_2_IKZF1plus is a frequent biomarker of adverse prognosis in Mexican pediatric patients with B-acute lymphoblastic leukemia.docx
Published 2024“…A decrease in OS was found in IKZF1<sup>MUT</sup> and CDKN2A/2B<sup>MUT</sup> patients, but the significance was lost after IKZF1<sup>plus</sup> was removed.…”