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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
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8641
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8642
Specificity of 1xSPS<sub>15</sub>, 2xCSL<sub>17</sub> and 2xCSL<sub>17</sub>mut probes as unlabeled competitors for Su(H).
Published 2021“…<p>EMSA data reveals that the addition of the unlabeled 1xSPS<sub>15</sub> and 2xCSL<sub>17</sub> probes, but not the 2xCSL<sub>17</sub>mut probe results in decreased Su(H) binding to the labeled 2xCSL<sub>17</sub> probe. 3.5nM labeled probe and 40nM Su(H) was used in indicated lanes. …”
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8643
Targeting hTERT Promoter G‑Quadruplex DNA Structures with Small-Molecule Ligand to Downregulate hTERT Expression for Triple-Negative Breast Cancer Therapy
Published 2024“…Human telomerase reverse transcriptase (hTERT) may have noncanonical functions in transcriptional regulation and metabolic reprogramming in cancer cells, but it is a challenging target. We thus developed small-molecule ligands targeting hTERT promoter G-quadruplex DNA structures (hTERT G4) to downregulate hTERT expression. …”
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8644
Developmental patterns of expression of tectal EphA3 and retinal ephrin-As and Tyr-602 phosphorylated-EphA4.
Published 2012“…The expression of ephrin-A2 extends along all the retina, presenting a decreasing naso-temporal gradient mainly in the RGCs. …”
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8645
Exploration of 2‑((Pyridin-4-ylmethyl)amino)nicotinamide Derivatives as Potent Reversal Agents against P‑Glycoprotein-Mediated Multidrug Resistance
Published 2017“…In-depth studies demonstrated <b>9n</b> has high potency (EC<sub>50</sub> = 119.6 ± 6.9 nM), low cytotoxicity, and long duration (>24 h) in reversing adriamycin (ADM) resistance in K562/A02 cells. …”
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8646
Flow of premises through the study.
Published 2024“…The daily volume of wine sold increased during the intervention period by 232 ml (95% CI [13, 487], <i>p</i> = 0.035) or 7.2% (95% CI [0.4%, 14.5%]). Daily revenues decreased by 5.0% (95% CI [9.6%, −0.3%], <i>p</i> = 0.038).…”
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8647
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8648
A synthetic lethal screen identifies the Vitamin D receptor as a novel gemcitabine sensitizer in pancreatic cancer cells
Published 2015“…A sublethal dose (50 nM) of the drug was used to model situations of limiting drug availability to PCa tumors in vivo. …”
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8649
High-performance thin-layer chromatogram of mouse brain ganglioside distribution in control (Ctl 1, Ctl 2) and experimental (VCS, #8566, #8568) brain tissue.
Published 2015“…Note the increase in GM1 in VCS animals and decreased GD1a, GT1a, GT1b, and GQ1b, in striatal (CD) and hippocampus (HP) samples.…”
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8650
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8651
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8652
Gally performs lateral transduction of over 200 kb of adjacent chromosomal DNA, including Perceval.
Published 2023“…Red bars indicate 40.1 kb steps of decreasing coverage from the <i>pac</i> site of Gally prophage, which could correspond to DNA packaged by a headful mechanism. …”
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8653
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8654
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8655
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8656
Supplementary Material for: Intrapapillary hemorrhage with adjacent peripapillary subretinal hemorrhage in a 9-year-old girl: A case report
Published 2025“…There have been no reports of patients younger than 10 years. We report a case of typical IHAPSH that occurred in a 9-year-old girl in the advanced stages of myopia. …”
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8657
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8658
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8659
Data_Sheet_1_Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis.pdf
Published 2020“…<p>Cholesterol biosynthesis is a multi-step process involving several subcellular compartments, including peroxisomes. …”
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8660
DataSheet_1_Safety, tolerability, pharmacokinetics and pharmacokinetic-pharmacodynamic modeling of cetagliptin in patients with type 2 diabetes mellitus.docx
Published 2024“…Meanwhile, a population PK/PD model was developed by a sequential two-step analysis approach using Phoenix.…”