Interaction of Ca²⁺ with the exit of proton channel H in bovine heart oxidase. by Tatiana Vygodina (456671)

“…The protonated state of D51 is then stabilized by multiple hydrogen bonding to S^II205 and S441. As proposed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074436#pone.0074436-Kamiya1" target="_blank">[44]</a>, the enol form of the S441-Y440 peptide bond returns to the initial keto form (the notorious proton transfer via the peptide bond S441-Y440 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074436#pone.0074436-Kamiya1" target="_blank">[44]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074436#pone.0074436-Tsukihara2" target="_blank">[45]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074436#pone.0074436-Yoshikawa4" target="_blank">[49]</a>) actually in two steps. …”

Platinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected Outcomes by Pavel Štarha (490367)

“…Complexes showed high <i>in vitro</i> cytotoxicity against nine human cancer cell lines (IC₅₀ ranging from 0.4 to 12.8 μM), including the <i>cisplatin</i>-resistant ovarian cancer cell line (A2780R; IC₅₀ = 1.0–3.5 μM). …”

CDK2/Speedy A localization in <i>Cdk2</i>^<i>T160A</i> spermatocytes. by Nathan Palmer (264897)

“…Percentages of mid-pachytene–stage nuclei with at least one telomere showing a decrease in telomeric CDK2 intensity of ≥50% (as compared with the average telomeric CDK2 intensity for that cell) are quantified in panel O. …”

Hereditable states as a function of vesicle size. by Nicholas Guttenberg (815547)

“…<p>In the GARD paper, the authors observed the trend that as the vesicle size <i>N</i>_max was increased, the number of heritable states decreased [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140663#pone.0140663.ref008" target="_blank">8</a>]. …”

Standard definitions of outcome variables [9]. by Nicolas Gaffan (15366964)

“…</p><p>Results</p><p>From 2001 to 2017–2018, household access to individual basic WASH services increased from 50.54% to 63.98% (APC = +1.44%), 5.39% to 13.29% (APC = +5.62%), and 2.12% to 10.11% (APC = +9.92%), respectively. …”

Activity of autologous plasma against cell-cell transmission of CAP256 viruses is strongly driven by VRC26 bnAb activity. by Lucia Reh (546554)

Photomicrographs showing NFILS-IR nerve fibers in TPL cervix (a) and a NFILS-IR nerve fascicle in NP corpus (b) by Berith K Tingåker (87814)

“…There is a significant decrease of IR-nerve fibres/mmin the term pregnant group compared to non-pregnant controls, p < 0.0001. …”

CAP256-VRC26 bnAbs maintain neutralization activity against cell-cell transmission of autologous viruses. by Lucia Reh (546554)

miR-17-5p overexpression and subsequent paclitaxel treatment induced mitochondrial pathway mediated apoptosis in A549-T24 cells. by Abhisek Chatterjee (584727)

“…(A) T24-miR-NC or T24-miR-17-5p cells were treated either with 24 nM or 50 nM paclitaxel for another 24 h. …”

Resveratrol Modulates the Cell Metabolome. by Zhe Wang (41178)

“…The red font represents the significantly increased metabolites (increased pool size>50%, p-value<0.05), and the green font represents the significantly decreased metabolites (decreased pool size>50%, p-value<0.05). …”

A Common KIF6 Polymorphism Increases Vulnerability to Low-Density Lipoprotein Cholesterol: Two Meta-Analyses and a Meta-Regression Analysis by Brian A. Ference (190898)

“…<div><h3>Background</h3><p>We sought to determine if a common polymorphism can influence vulnerability to LDL cholesterol, and thereby influence the clinical benefit derived from therapies that reduce LDL cholesterol.…”

Extracellular Heat Shock Protein (Hsp)70 and Hsp90α Assist in Matrix Metalloproteinase-2 Activation and Breast Cancer Cell Migration and Invasion by Jessica D. Sims (224825)

“…Obtaining a better understanding of migration and invasion, two early steps in metastasis, is critical for the development of treatments that inhibit breast cancer metastasis. …”

The effects of cytokine priming on the virus replication in moDCs. by Veera Arilahti (560851)

TipDC transcriptome. by Svetlana Rezinciuc (4775136)

“…<p>At zero or nine days following intranasal infection of mice with IAV at (EID₅₀: 2000,) the lungs were homogenized, and cells extracted. …”

A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase by Kenneth W. Yip (257594)

“…Because there is no known chemical UROD inhibitor suitable for use in translational studies, we aimed to design, synthesize, and characterize such a compound. …”

Infection-induced changes in DC protein abundance and localization. by Svetlana Rezinciuc (4775136)

AIF1L knockout clones exhibit an impaired actomyosin contractility reserve. by Mako Yasuda-Yamahara (5509151)

Celastrol is a potent p536 inhibitor. by Longjiang Shao (385841)

S1 Dataset - by Pamela Bakkabulindi (12914980)

“…</p><p>Methods</p><p>An implementation study in which 5 health facilities were stratified and randomized in two groups to (i) receive a package of interventions including monthly health unit immunization data audit meetings, and defaulter tracking and linkage and (ii) to serve as a control group was conducted between July and September 2020. …”

Experiment 3 –trial E. by Ottavia Benedicenti (9100619)