An Integrated Disease/Pharmacokinetic/Pharmacodynamic Model Suggests Improved Interleukin-21 Regimens Validated Prospectively for Mouse Solid Cancers by Moran Elishmereni (203218)

“…Simulations of the verified model surfaced important therapeutic insights: (1) Fractionating the standard daily regimen (50 µg/dose) into a twice daily schedule (25 µg/dose) is advantageous, yielding a significantly lower tumor mass (45% decrease); (2) A low-dose (12 µg/day) regimen exerts a response similar to that obtained under the 50 µg/day treatment, suggestive of an equally efficacious dose with potentially reduced toxicity. …”

<b>Genome assembly at chromosome level and evolutionary analysis of </b><i><b>Coregonus ussurinsis</b></i><b> Berg</b> by Tianqing Huang (9743483)

“…The sequence length was 2,627.19 Mb with a contig N50 length of 4.27 Mb. Then 3,109 contigs were assembled into scaffolds, resulting in a genome assembly with 40 chromosomes and a scaffold N50 length of 62.20 Mb, and the size of the genome was 2.51 Gb, and the integrity was more than 95% by BUSCO test. …”

Data_Sheet_1_Microbial Interactions With Dissolved Organic Matter Drive Carbon Dynamics and Community Succession.docx by Xiaoqin Wu (470428)

“…In this study, we fed sediment-derived dissolved organic matter (DOM) to groundwater microbes and continually analyzed microbial transformation of DOM over a 50-day incubation. …”

Nutritional and Protein Deficiencies in the Short Term following Both Gastric Bypass and Gastric Banding by Judith Aron-Wisnewsky (544060)

“…Serum analysis demonstrated a continuous decrease in prealbumin during the follow-up, indicating mild protein depletion in 21 and 57% of GBP patients and 50 and 63% of AGB patients, respectively, at T1 and T3. …”

Increased Autophagy in <i>daf-2/</i>insulin/IGF Receptor Mutants Is Independent of the <i>daf-16</i>/FOXO and <i>pha-4</i>/FOXA Transcription Factors by Malene Hansen (10367)

“…The mean lifespan of <i>daf-2(e1370)</i> animals was shortened 12.5% by <i>pha-4</i> RNAi ([<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0040024#pgen-0040024-b028" target="_blank">28</a>] and data not shown), and we measured an 11% decrease in puncta in <i>daf-2(e1370)</i> animals fed <i>pha-4</i> RNAi. …”

Data_Sheet_1_Seagrass Colonization Alters Diversity, Abundance, Taxonomic, and Functional Community Structure of Benthic Microbial Eukaryotes.docx by Ying Pan (90050)

Image_2_The DOF-Domain Transcription Factor ZmDOF36 Positively Regulates Starch Synthesis in Transgenic Maize.JPEG by Jiandong Wu (737216)

Supplementary Material for: Population-Attributable Risk Fractions for Antiplatelets and Anticoagulants in Spontaneous Intracranial Hemorrhages by Choi H.H. (14759125)

DCAF13 promotes triple-negative breast cancer metastasis by mediating DTX3 mRNA degradation by Jiazhe Liu (9754115)

Image_1_The DOF-Domain Transcription Factor ZmDOF36 Positively Regulates Starch Synthesis in Transgenic Maize.JPEG by Jiandong Wu (737216)

Accelerometric outcomes of motor function related to clinical evaluations and muscle involvement in dystrophic dogs by Mutsuki Kuraoka (6069350)

DUX4 Binding to Retroelements Creates Promoters That Are Active in FSHD Muscle and Testis by Janet M. Young (79201)

Video_1_Robustness and Scalability of Regional Climate Projections Over Europe.mp4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

Accelerated Immunodeficiency by Anti-CCR5 Treatment in HIV Infection by Ariel D. Weinberger (169848)

“…The model shows that the R5-to-X4 switch occurs as CD4⁺ T cell activation levels increase above a threshold and as CD4⁺ T cell counts decrease below a threshold during late-stage HIV infection. …”

Supplementary Material for: Effect of Dupilumab on Depression in Asthma with Eosinophilic Chronic Rhinosinusitis in the Japanese Population by Koya T. (4155160)

“…In the evaluation 4 months after dupilumab treatment, the PHQ-9 score was significantly reduced, and the decrease was remarkable in patients whose nasal symptom score was reduced by 50% or more. …”

Video_2_Robustness and Scalability of Regional Climate Projections Over Europe.MP4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

PHOSPHORUS FERTILIZATION AND SOIL TEXTURE AFFECT POTATO YIELD by JÉSSYCA DELLINHARES LOPES MARTINS (6117419)

“…<div><p>ABSTRACT Potato (Solanum tuberosum L.) is a nutritionally demanding crop, and phosphorus (P) is a nutrient that exerts a large effect on tuber yield. …”

Table1_Effect of fungicidal contamination on survival, morphology, and cellular immunity of Apis mellifera (Hymenoptera: Apidae).DOCX by Gurleen Kaur (11041128)

“…Our results revealed a continuous, concentration-dependent decrease in brood survival after 24 h of treatment to the capping and emergence stages. …”

Table1_Effect of fungicidal contamination on survival, morphology, and cellular immunity of Apis mellifera (Hymenoptera: Apidae).DOCX by Gurleen Kaur (11041128)

“…Our results revealed a continuous, concentration-dependent decrease in brood survival after 24 h of treatment to the capping and emergence stages. …”

Tonotopic differences in outer hair cell properties. by Eric Wersinger (238206)

“…Representative records of currents evoked by a series of voltage steps (100 ms in duration) from −131 mV to 49 mV in 10 mV increments (with an interpulse holding potential of −81 mV) show an increase in outward current (at 49 mV) from 2.08±0.09 nA in outer hair cells from apical regions (n = 25, F) to 7.24±0.4 nA in outer hair cells from basal regions (n = 23 basal, G). …”