Evidence for Substrate Preorganization in the Peptidylglycine α-Amidating Monooxygenase Reaction Describing the Contribution of Ground State Structure to Hydrogen Tunneling by Neil R. McIntyre (2249155)

“…The first step, the copper-, ascorbate-, and O₂-dependent stereospecific hydroxylation at the α-carbon of the C-terminal glycine, is catalyzed by peptidylglycine α-hydroxylating monooxygenase (PHM). …”

Evidence for Substrate Preorganization in the Peptidylglycine α-Amidating Monooxygenase Reaction Describing the Contribution of Ground State Structure to Hydrogen Tunneling by Neil R. McIntyre (2249155)

“…The first step, the copper-, ascorbate-, and O₂-dependent stereospecific hydroxylation at the α-carbon of the C-terminal glycine, is catalyzed by peptidylglycine α-hydroxylating monooxygenase (PHM). …”

Evidence for Substrate Preorganization in the Peptidylglycine α-Amidating Monooxygenase Reaction Describing the Contribution of Ground State Structure to Hydrogen Tunneling by Neil R. McIntyre (2249155)

“…The first step, the copper-, ascorbate-, and O₂-dependent stereospecific hydroxylation at the α-carbon of the C-terminal glycine, is catalyzed by peptidylglycine α-hydroxylating monooxygenase (PHM). …”

Table_1_Silicon Enhances Biomass and Grain Yield in an Ancient Crop Tef [Eragrostis tef (Zucc.) Trotter].XLSX by Ayalew Ligaba-Osena (4886842)

“…A slight decrease in grain Ca, P, S, and Mn was also observed with increasing Si treatment. …”

Presentation_1_Stay-at-home and face mask policy intentions inconsistent with incidence and fatality during the US COVID-19 pandemic.pdf by Samuel X. Wu (13954158)

“…States with SAH orders showed a potential 50–60% decrease in infection and fatality during the SAH period (about 45 days). …”

Local reward learning and GRS-based learning became more pronounced over the course of adolescence. by Marco K. Wittmann (14710470)

Test of the most likely period associated with orang-utan population decline. by Reeta Sharma (117636)

“…<p>Natural logarithms of the Bayes Factors (BF) have been computed to determine during which of the important phases the populations started to decrease. a) The BF values of parameter <i>T</i> (time since the beginning of the population collapse) for all orang-utan populations were computed for each 500 year time steps and are plotted for last 50,000 years. …”

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

The Biodiversity of the Mediterranean Sea: Estimates, Patterns, and Threats by Marta Coll (213022)

Video_1_Virtual Footprints Can Improve Walking Performance in People With Parkinson's Disease.MP4 by Luis I. Gómez-Jordana (5640137)

“…In all conditions the PD group showed reduced levels of gait variability (p < 0.05) while the HC group did not decrease. For step velocity there was a significant increase in the temporal conditions, the spatial conditions and of the interaction between the two for both groups of participants (p < 0.05). …”

DataSheet_1_Multicriteria assessment of conservation agriculture systems.pdf by Guillaume Adeux (7882007)

“…Nevertheless, few studies have evaluated the interactive effect of these three fundamental pillars on a multicriteria basis. Here, we mobilize data from the French AGROSYST database, which gathers all farming practices and performances of the 3000 farms involved in the French DEPHY farmers’ network. …”

Data Sheet 1_Anti-HLA antibodies bound to monocytes altered antibody-mediated platelet phagocytosis and led to mild thrombocytopenia.pdf by Xiuzhang Xu (22363618)

Data_Sheet_1_Repeated Vessel Interactions and Climate- or Fishery-Driven Changes in Prey Density Limit Energy Acquisition by Foraging Blue Whales.docx by Marie Guilpin (9198812)

“…We specifically examined the energetic consequences of a demonstrated reduction in dive duration caused by vessel proximity, and of krill density reductions potentially resulting from krill exploitation or climate change. …”

Synaptic efficacy is reduced during UP states. by Brendon O. Watson (268774)

“…In purple are EPSP percent changes for 4 recorded interneurons, which show heterogeneous changes during the UP state ranging from a 30% increase to a 65% decrease (mean: 26.5% decrease, standard deviation 50.0%; see gray bar at left of graph). …”

Effects of body habitus on contrast-induced acute kidney injury after percutaneous coronary intervention by Toshiki Kuno (450365)

“…Indeed, low BMI was a significant predictor of a V/CrCl ratio > 3 (OR per unit decrease in BMI, 1.08 [1.05–1.10]; P < 0.001).…”

DataSheet1_Eluxadoline Versus Antispasmodics in the Treatment of Irritable Bowel Syndrome: An Adjusted Indirect Treatment Comparison Meta-analysis.PDF by Di Qin (107446)

“…The secondary efficacy outcome was the relief of global IBS symptoms, defined by a composite response of a decrease in abdominal pain and improvement in stool consistency on the same day for at least 50% of the days assessed. …”

Metformin extends median lifespan via an AMPK and LKB1-dependent mechanism. by Brian Onken (86790)

“…Pooled data for four independent trials with the <i>par-4(it57)</i> mutants show a decrease in median lifespan (9 days for 50 mM metformin plates vs. 10 days for 0 mM metformin; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008758#pone.0008758.s005" target="_blank">Table S1F</a>) and a significantly left-shifted survival curve for 50 mM metformin-treated animals (<i>P</i> = 0.0063, Log-rank; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008758#pone.0008758.s005" target="_blank">Table S1F</a>). …”

Administration of propranolol increased voltage-gated potassium current. by Chunhua Zhang (148898)

“…(B) HIS led to a significant decrease in <i>I</i>_K while administration of Prop resulted in a marked potentiation in <i>I</i>_K density (*p<0.05, compared with CON, two sample <i>t</i>-Test; ##p<0.01, compared with NS). …”

Table_1_Short-Term Physical Inactivity Induces Endothelial Dysfunction.docx by Kelly A. Bowden Davies (7247510)

“…</p>Design<p>Twenty-eight habitually active (≥10,000 steps/day) participants (18 female, 10 male; age 32 ± 11 years; BMI 24.3 ± 2.5 kg/m²) were assessed at baseline, following 14 days of step-reduction and 14 days after resuming habitual activity.…”

The <i>Citrobacter rodentium</i> type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses by Cedric N. Berger (4544008)