DataSheet_4_Evaluating NetMHCpan performance on non-European HLA alleles not present in training data.xlsx by Thomas Karl Atkins (17791715)

“…Thus, investigating the composition of training datasets used in machine learning models with healthcare applications is vital to ensure equity. Two such machine learning models are NetMHCpan-4.1 and NetMHCIIpan-4.0, used to predict antigen binding scores to major histocompatibility complex class I and II molecules, respectively. …”

DataSheet_3_Evaluating NetMHCpan performance on non-European HLA alleles not present in training data.xlsx by Thomas Karl Atkins (17791715)

“…Thus, investigating the composition of training datasets used in machine learning models with healthcare applications is vital to ensure equity. Two such machine learning models are NetMHCpan-4.1 and NetMHCIIpan-4.0, used to predict antigen binding scores to major histocompatibility complex class I and II molecules, respectively. …”

Probing the auditory nerve using round-window response in control and ouabain-poisoned cochleae. by Charlène Batrel (3639406)

“…Note that below 2 kHz (light-coloured area), the neural index amplitude decreases because of the phase locked response of fibers and their cancelation by opposite polarities. …”

Table 6_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…The alterations in these candidate proteins were further validated by ELISA to evaluate their potential as diagnostic biomarkers for colorectal adenoma.</p>Results<p>In two independent cohorts, we identified two candidate biomarkers, apolipoprotein A4 (APOA4) and filamin A (FLNA), through a multi-step selection process involving ANOVA p-value screening, sparse partial least squares discriminant analysis (sPLS-DA), and LASSO regression analysis. …”

Table 3_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…The alterations in these candidate proteins were further validated by ELISA to evaluate their potential as diagnostic biomarkers for colorectal adenoma.</p>Results<p>In two independent cohorts, we identified two candidate biomarkers, apolipoprotein A4 (APOA4) and filamin A (FLNA), through a multi-step selection process involving ANOVA p-value screening, sparse partial least squares discriminant analysis (sPLS-DA), and LASSO regression analysis. …”

Table 1_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…The alterations in these candidate proteins were further validated by ELISA to evaluate their potential as diagnostic biomarkers for colorectal adenoma.</p>Results<p>In two independent cohorts, we identified two candidate biomarkers, apolipoprotein A4 (APOA4) and filamin A (FLNA), through a multi-step selection process involving ANOVA p-value screening, sparse partial least squares discriminant analysis (sPLS-DA), and LASSO regression analysis. …”

Table 4_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…The alterations in these candidate proteins were further validated by ELISA to evaluate their potential as diagnostic biomarkers for colorectal adenoma.</p>Results<p>In two independent cohorts, we identified two candidate biomarkers, apolipoprotein A4 (APOA4) and filamin A (FLNA), through a multi-step selection process involving ANOVA p-value screening, sparse partial least squares discriminant analysis (sPLS-DA), and LASSO regression analysis. …”

Data Sheet 1_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.docx by Chengli Yu (1445185)

“…The alterations in these candidate proteins were further validated by ELISA to evaluate their potential as diagnostic biomarkers for colorectal adenoma.</p>Results<p>In two independent cohorts, we identified two candidate biomarkers, apolipoprotein A4 (APOA4) and filamin A (FLNA), through a multi-step selection process involving ANOVA p-value screening, sparse partial least squares discriminant analysis (sPLS-DA), and LASSO regression analysis. …”

Table 5_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…The alterations in these candidate proteins were further validated by ELISA to evaluate their potential as diagnostic biomarkers for colorectal adenoma.</p>Results<p>In two independent cohorts, we identified two candidate biomarkers, apolipoprotein A4 (APOA4) and filamin A (FLNA), through a multi-step selection process involving ANOVA p-value screening, sparse partial least squares discriminant analysis (sPLS-DA), and LASSO regression analysis. …”

Blind Predictions of DNA and RNA Tweezers Experiments with Force and Torque by Fang-Chieh Chou (414477)

“…These calculations recovered the experimental bending persistence length of dsRNA within the error of the simulations and accurately predicted that dsRNA's “spring-like” conformation would give a two-fold decrease of stretch modulus relative to dsDNA. …”

Modulation of spinal inhibitory reflexes depends on the frequency of transcutaneous electrical nerve stimulation in spastic stroke survivors by Soichiro Koyama (2807140)

“…<p>Neurophysiological studies in healthy subjects suggest that increased spinal inhibitory reflexes from the tibialis anterior (TA) muscle to the soleus (SOL) muscle might contribute to decreased spasticity. While 50 Hz is an effective frequency for transcutaneous electrical nerve stimulation (TENS) in healthy subjects, in stroke survivors, the effects of TENS on spinal reflex circuits and its appropriate frequency are not well known. …”

Image_2_Temperature–Induced Hatch Failure and Nauplii Malformation in Antarctic Krill.JPEG by Frances A. Perry (7037123)

“…The hatching success of embryo batches varied enormously, from 0 to 98% (mean 27%). Both field and laboratory experiments showed that hatching success decreased markedly above 3.0°C. …”

Image_1_Temperature–Induced Hatch Failure and Nauplii Malformation in Antarctic Krill.JPEG by Frances A. Perry (7037123)

“…The hatching success of embryo batches varied enormously, from 0 to 98% (mean 27%). Both field and laboratory experiments showed that hatching success decreased markedly above 3.0°C. …”

Probability of establishing a sylvatic ZIKV transmission cycle. by Benjamin M. Althouse (116177)

“…Other parameters: mean mosquito lifespan = 7 days; mean ZIKV recovery in NHP = 4 days; mosquito vertical transmission of ZIKV = 0; rate of yearly ZIKV introduction = 0.…”

Assessment of in vitro and in vivo effect of Quercetin 3-Glucoside, Oxyresveratrol and Quercetin O-Hexoside against Leishmania tropica by Kashif Iqbal (6504587)

“…The Quercetin 3-Glucoside shows mean inhibition of extracellular promastigotes after 48 hours at 50, 100, 150, 200 µg/mL were 91.02 ± 0.12, 94.50 ± 0.07, 96.15 ± 0.17 and 97.01 ± 0.08 % respectively. …”

Table_1_Controlled Reduction of Genomic Heterozygosity in an Industrial Yeast Strain Reveals Wide Cryptic Phenotypic Variation.xlsx by Nadia M. V. Sampaio (5330723)

“…In this study, we took a step toward exploring this question by conducting an initial functional characterization of JAY270’s heteroalleles. …”

Table_1_Predicting Responses to Psychedelics: A Prospective Study.docx by Eline C. H. M. Haijen (5923544)

“…Psychological well-being was increased 2 weeks after a psychedelic experience and remained at this level after 4 weeks. …”

A Latex Metabolite Benefits Plant Fitness under Root Herbivore Attack by Meret Huber (842949)

“…Silencing the germacrene A synthase ToGAS1, an enzyme that was identified to catalyze the first committed step of TA-G biosynthesis, resulted in a 90% reduction of TA-G levels and a pronounced increase in <i>M</i>. …”

Acute Undifferentiated Febrile Illness in Rural Cambodia: A 3-Year Prospective Observational Study by Tara C. Mueller (587528)

“…As a first step towards developing such guidelines, a 3-year cross-sectional prospective observational study was designed to investigate the causes of acute malaria-negative febrile illness in Cambodia. …”

Table1_Causal effects and metabolites mediators between immune cell and risk of colorectal cancer: a Mendelian randomization study.xlsx by Qian Yang (300330)

“…Additionally, a two-step MR strategy was utilized to pinpoint potential metabolites that mediate this effect. …”