Selective USP7 inhibitor P217564 regulates the stability of USP7. by Feng Wang (44414)

“…<p>(A) P217564 decreases the USP7 level in a dose-dependent manner. …”

Protein Crystallization in the Presence of a Metastable Liquid–Liquid Phase Separation by Ralph Maier (7865357)

“…SAXS and SANS show a monotonous growth of the crystals and a decrease of the overall material in the sample. We thus conclude that the existence of a metastable LLPS is not a sufficient condition for a two-step nucleation process. …”

Time course of the decline in [Ca²⁺]_mito. by Michele Scorzeto (466342)

Atrasentan does not ameliorate established podocyte injury in adriamycin nephropathy. by Roderick J. Tan (483502)

“…(H) Representative glomerulus from mouse treated with adriamycin and sacrificed at 35 days (left panel). Atrasentan at a dose of 7 mg/kg (middle panel) or 20 mg/kg (right panel) did not improve the loss of linear staining for nephrin (white arrows), the areas of complete nephrin disruption (asterisk), or the decrease in WT1-positive nuclei (yellow arrowheads). …”

DataSheet1_Mildly Increased Renin Expression in the Absence of Kidney Injury in the Murine Transverse Aortic Constriction Model.pdf by Marian Wesseling (8807429)

“…<p>Cardiorenal syndrome type 2 is characterized by kidney failure as a consequence of heart failure that affects >50% of heart failure patients. …”

DataSheet_1_TH2/TH1 Shift Under Ibrutinib Treatment in Chronic Lymphocytic Leukemia.pdf by Maria Cristina Puzzolo (10649975)

“…We documented a progressive decrease of CD3+CD4+IL-4+ T cells (Th2), that was significant at M8 and at M12 (p=0.019, p=0.002), a relative increase in the CD3+CD4+IFNγ+ T cells (Th1) and a decrease of CD3+CD4+IL-17+ (Th17) cells that was maintained up to M18 (M8 vs D0 p=0.003, M12 vs D0 p=0.003, M18 vs D0 p=0.004) of ibrutinib treatment. …”

Mouse survival curves after carbon nanomaterial injection. by Alan C. L. Tang (175971)

“…No mortality was observed among the CNC-treated mice at 25 μg/g b.w. n = 12 for CNC, and C₆₀ injected mice. n = 11 for NS, PVA, MWCNT, and SWCNT injected mice. Red square, 50 μg/g; black dot, 25 μg/g; black cross, 12.5 μg/g.…”

End-point variability and smallest effective ISS. by James P. Herman (304807)

“…The smallest effective ISS is the minimum ISS size for which a particular subject showed a significant adaptive decrease in gain (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059731#pone-0059731-g002" target="_blank">Figure 2A</a>). …”

Phase difference, spatial synchrony, and phase coherence plots. by Yi Hu (58993)

“…The error bars are standard deviation from mean phase difference. <b>b/f</b>, Phase difference from Huangzhong and Fengxian (as a function of population size for neighboring counties, within 70 km of Huangzhong and 50 km of Fengxian). …”

Changes in digestive enzymes activities during the initial ontogeny of wolf cichlid, Parachromis dovii (Perciformes: Cichlidae) by Carlos Alfonso Frías-Quintana (6675845)

Effect of <i>Nat10</i> on ribosome assembly. by Masato Taoka (189054)

“…Ribosomal and polysomal fractions prepared from strain SP6 (upper panel) or Nat10_G285D mutant (lower panel), grown at 30°C in YE medium were analyzed with 15–50% sucrose density gradient centrifugation. The UV profiles (A₂₅₄) of the separation are depicted. …”

Loss of mesenchymal <i>Srg3</i> disrupted BMP signaling and caused defective chondrogenesis in forelimb buds. by Shin Jeon (2559289)

Renal adaptations in hypertension preserve K+ while minimizing Na+ retention during pregnancy. by Melissa Stadt (17964875)

Mapping of mAb neutralizing activity. by Tysheena P. Charles (3385586)

“…(<b>G)</b> The log10 fold increase or decrease in IC₅₀ titer of each mutant PV relative to the parental BG505 PV is shown. …”

EFFECTS OF AEROBIC EXERCISE ON BODY MORPHOLOGY IN OBESE UNIVERSITY STUDENTS by Ma Jin (12651607)

Reactive microsphere motion illustrates the discrete nature of bond formation events and force loading. by Brian J. Schmidt (255745)

“…An increase in the magnitude of the fluctuations of V_S,X was observed with the decrease in stiffness relative to (A). (C) Results for a 10 µm-diameter sphere with a freely-jointed chain model of force deformation, (6). …”

Effect of rTMS on X cells. by Nelson Espinosa (356237)

Effects of FAK inhibitor Y15 and RGD peptide on cumulus expansion <i>in vitro</i>. by Hiroya Kitasaka (4840218)

“…Non-expanded COCs were selected, and 50 COCs were cultured in a 50 μl drop of defined medium containing 1% FBS and 100 ng/ml AREG. …”

Sialylation of Prion Protein Controls the Rate of Prion Amplification, the Cross-Species Barrier, the Ratio of PrP^Sc Glycoform and Prion Infectivity by Elizaveta Katorcha (628696)

Superior Hard but Quickly Reversible Si–O–Si Network Enables Scalable Fabrication of Transparent, Self-Healing, Robust, and Programmable Multifunctional Nanocomposite Coatings by Yi Hou (148620)

“…The highly cross-linked continuous network endows the coating with a hardness (<i>H</i> = 0.83 GPa) higher than those of most polymers (<i>H</i> < 0.3 GPa), while the uniformly dispersed micelles decrease the Young’s modulus (<i>E</i> = 5.89 GPa) to a value as low as that of common plastics, resulting in excellent hardness and flexibility, with an <i>H</i>/<i>E</i> of 14.1% and an elastic recovery rate (<i>W</i>_e) of 86.3%. …”