Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by Sneha P. (3926957)

“…Missense mutations of the HNF1A were retrieved from public databases and subjected to a three-step computational mutational analysis to identify the underlying mechanism. …”

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

Graphical representation of a stepped-wedge design with 6 sequences. by Mirjam Moerbeek (8603520)

Subjects:

C2GnT1 gene knockdown decreases C2-O-sLe^X glycoproteins and C2GnT1 activity. by Catherine A. St. Hill (357388)

“…Note the absence of a detected C2GnT1 protein 50 kDa band. (D) We observed a 30–40% decrease in reactivity with CHO-131 mAb by flow cytometry for LS174T and HepG2 cells that contained C2GnT1 shRNA. …”

Differential gene expression assay EC₅₀ values in Huh-7 cells and PHH. by Xuan G. Luong (9761423)

Advancing the science of NOWS research. by Sarah E. Maylott (14560785)

“…It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. Understanding which infants will develop NOWS soon after birth could reduce hospital stays for infants who do not develop NOWS and decrease burdens on hospitals and clinicians. …”

Protocol measures. by Sarah E. Maylott (14560785)

“…It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. Understanding which infants will develop NOWS soon after birth could reduce hospital stays for infants who do not develop NOWS and decrease burdens on hospitals and clinicians. …”

Cry variables. by Sarah E. Maylott (14560785)

“…It is not known which infants will develop NOWS, therefore, the current hospital standard-of-care dictates a 96-hour observational hold. Understanding which infants will develop NOWS soon after birth could reduce hospital stays for infants who do not develop NOWS and decrease burdens on hospitals and clinicians. …”

Phosphorylation as an Effective Tool to Improve Stability and Reduce Toxicity of Antimicrobial Peptides by Zufang Ba (11036420)

“…Phosphorylation can reduce toxicity and improve the stability of AMPs. Based on these, we designed a series of peptides and their corresponding phosphorylated forms. …”

Treatment with mitochondrial shuttle inhibitors, GKA50, Ranolazine and glucose results in significant decreases in superoxide concentration as detected by coelenterazine chemilumin... by Laura L. Bronsart (844933)

Data_Sheet_1_Marathon Running Increases Synthesis and Decreases Catabolism of Joint Cartilage Type II Collagen Accompanied by High-Energy Demands and an Inflamatory Reaction.PDF by José A. Hernández-Hermoso (11545663)

“…Mean sC2C levels (220.83 ± 39.50 ng/ml) decreased post-race (188.67 ± 38.52 ng/ml) (p = 0.002). …”

Fig 2 - by Min Sub Sim (8193564)

Different steps of the fabrication process. by Md. Abu Daud (21485629)

Schematic illustration of the possible steps for the rupture of a ‘single GUV’. by Md. Tariqul Islam Bhuiyan (18794375)

Correlation between hub genes and 50 hallmark signaling pathways. by Jiyong Zhang (2498740)

Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues. by Kumaraswamy Naidu Chitrala (612025)

“…<p>Regions (α-helices, β-sheets, and loops) showing an average increase or decrease of RMSF in the MTs compared to the WT; RMSF of a particular structure is taken to be increased or decreased if there is an average change in RMSF of >0.03 nm in at least ≥50% of its residues.…”

Resveratrol Prevents Oxidative Stress-Induced Senescence and Proliferative Dysfunction by Activating the AMPK-FOXO3 Cascade in Cultured Primary Human Keratinocytes by Yasuo Ido (172159)

“…In addition, we found that treatment of keratinocytes with Ex527, a specific inhibitor of sirtuin 1 (SIRT1), attenuated the ability of resveratrol to suppress senescence. …”

DMB treatment improved neurological deficit and decreased infarct volume 24 h after MCAO. by Huinan Zhang (849524)

The material parameters of the 50 MPa concrete for the simulations [26]. by Xiaochao Jin (3993236)