CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS by ELJILANY, ISLAM AHMED SAYED AHMED

“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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Attenuation of WNT signaling by DKK-1 and -2 regulates BMP2-induced osteoblast differentiation and expression of OPG, RANKL and M-CSF-5 by Ken-ichi Fujita (83343)

“…Total RNA was extracted and mRNA levels of M-CSF were determined using real-time RT-PCR. Data are shown as means ± SD based on 5 independent experiments. Number signs and asterisks indicate significant changes (< 0.005) compared to untreated cells and Wnt3a-treated cells, respectively. , Dkk1 restores Wnt3a-dependent decrease in M-CSF protein secreted into the extracellular milieu. …”

Effects of administration regimen on antitumor activity, TK activity and viral replication. by Daniel Abate-Daga (200715)

“…Group A received 4 doses of 2×10¹⁰ vp ICOVIR5-TK-L on days 0, 1, 7 and 8, and 6 ip doses of 100 mg/kg GCV on days 4, 5, 6, 11, 12 and 13. …”

Combination effect of bradycardia, ApoE4 allele and increased vessel stiffness. by Christina Rose Kyrtsos (810935)

“…There was a small decrease in the number of neurons at the final simulation endpoint (<10%). …”

RS modifies the BRL effects in RC cell population cultures. by Yuji Yoshiko (245190)

“…<p>Cells in osteogenic medium were chronically treated with or without BRL in combination with or without RS or fenofibrate for 14 days. (A and B) A combination of 100 nM BRL and 1–2.5% RS elicits a reciprocal increase in adipocytes (A) and decrease in bone nodules (B). …”

Predictive performance for invasive populations. by Dennis Rödder (131552)

“…<p>It largely decrease at lower latitudes in 100 models computed with random subsets of predictors (A, B; the number of models predicting each record is indicated), but not in a Maxent model derived from natural history criteria (C; Maxent values per record is indicated) (filled dots: native records; open triangles: invasive records). …”

Theoretical analysis of electrode size. by Sadullah Canakci (4439137)

“…<p>Figure shows SPW-Rs computed for different size electrodes (point, 100 × 100 μm², 300 × 300 μm², 1 × 1 mm², 2 × 2 mm², and 4 × 4 mm²). …”

Individual changes in global QoL. by Aurore Goineau (5076344)

“…There is an important decrease of QoL (≥ 20 points) for 13 patients and a moderate decrease in QoL (10 to 20 points) in 17 patients.…”

Hospitalization and mortality by diabetes mellitus in children: analysis of temporal series by Maria de Fátima Garcia Lopes Merino (8141760)

“…Conclusion: however, there was a decrease in infant mortality and increase in hospitalizations.…”

Simulation results of MR-PL. by Anyi Yang (16643634)

“…The error bar represents twice variance in type I error rate over 100 replications. Notably, the error bar tends to degenerate to a point for those settings with too small variance. …”

Changes to chromatin state with PRMT5 inhibition. by Shelby L. Sloan (10803222)

“…(D) Immunoblot analysis indicates a time dependent decrease in MYC protein after treatment with C220 in 17–71 (100 nM) and CLBL-1 (20 nM). …”

Evolution of linkage disequilibrium for different sample sizes and distances. by Sophie Bouchet (177842)

“…After correcting for background structure, mean r² decreased with distance from 0.2 (for the 0–10 kb distance class) to 0.02 and stabilized after 100 kb (B). …”

Nuclear import of Avian Sarcoma Virus integrase is facilitated by host cell factors-2 by Mark D Andrake (95479)

“…Quantitative analysis of nuclear import of various GST fusion proteins with (+ comp) and without (no comp) competitor. More than 100 cells were counted for each experimental condition and the percentage of cells that had a mostly nuclear staining for the fusion protein was calculated. …”

Measurement of the impedance of the HBEC monolayers during coculture with IRBC. by Ronan Jambou (80268)

“…A) show decrease of impedance when HBEC monolayer is co-cultured with IRBC(3Ci) or IRBC(3Ci)+NRBC (vol/vol), but not when co-cultured with normal RBC). …”

Development and functional characterization of a tissue-engineered blood-air barrier model for <i>in vitro</i> applications by Neval Sevinc Ozdemir (22143730)

“…TEER was measured as 44 ± 5.0 Ω·cm² with a permeability coefficient (P_app) of 2–5 × 10⁻⁶ cm/s against fluorescein.…”

Model robustness to noise. by Jesús M. Miró-Bueno (196921)

“…The changed rates are hour, hour, molecules hour, hour and molecules hour. In particular, we multiplied the rates and by 100 to obtain a low number of molecules. …”

Other glycines substitutions that destabilize BH4-Bcl-2’s by Giovanni Monaco (452223)

“…Data points represent means ± SEM. * indicates a statistically significant difference from vehicle control.…”

Sequence gaps exclusive to both Archaea and Microsporidia 16S rRNAs. by Chaitanya Muralidhara (223748)

“…(<i>a</i>) The 100 gaps conserved in both the Archaea and Microsporidia map to the entire substructures I–III in the secondary structure model of the bacterium <i>E. coli</i> <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018768#pone.0018768-Cannone1" target="_blank">[14]</a>. …”

PDBu (1 µM) increases the amplitude of outward K⁺ currents. by Sébastien Hayoz (5656207)

“…<p>Panel A: K⁺ currents elicited by linear voltage ramps varying from −100 to 100 mV. …”

Overview of birth-death model and main results. by Alexander S. Moffett (8250291)

“…For each pair (λ₀, <i>c</i>) we calculated the mean extinction time for all (<i>n</i>, <i>m</i>) pairs satisfying <i>n</i> ≥ 0, <i>m</i> ≥ 0, and <i>n</i> + <i>m</i> ≤ 100 with the QS and AO strategies. …”