Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

HFA decreased expression of osteoclastic markers in alveolar bone. by Mani Alikhani (5180768)

Increasing temperature decreases oxygen concentration and decreasing oxygen content decreases neuronal excitability. by Yuguo Yu (172221)

“…Increasing temperature can dramatically decrease oxygen levels. B. Response of layer 2/3 pyramidal cells (n = 5) to the intracellular injection of a depolarizing current pulse (200 pA, 500 ms) at different temperatures (same experiments as in A). …”

Dispersion-temperature of microgels decreases at lower pHs. by Chi-Shuo Chen (234719)

“…<p>As pH is reduced from 8.0 (black) to 7.7 (blue) to 7.5 (red) to 7.3 (green), non-linear microgel dispersion-temperature changes were observed while pH decreases. …”

Root index data of tomato after two planting stages. by Hongyi Pan (5706971)

Vacuolar dynamics after a rapid temperature decrease. by Noriaki Kadohama (382080)

“…<p>Vacuolar membrane labeled with FM1-43 (green) and chlorophyll fluorescence (magenta) in palisade mesophyll cells of saintpaulia leaf were observed before (A) and 10 min after (B) a rapid temperature decrease from 25°C to 5°C and kept at 5°C for 1 min. …”

Energetics of Ionized Water Molecules in the H‑Bond Network near the Ca²⁺ and Cl^– Binding Sites in Photosystem II by Keisuke Saito (516747)

“…It seems likely that Ca²⁺ plays a role in not only (i) maintaining the H-bond network and facilitating TyrZ oxidation [tuning <i>E</i>_m(TyrZ)] but also (ii) providing the valence of +2, decreasing the p<i>K</i>_a of the ligand molecule (W1), and facilitating the release of the proton from W1 in the S₂ to S₃ transition together with Cl^–.…”

Heterozygous deletion of <i>ERG251-A</i> leads to a transcriptional response in filamentation regulation. by Xin Zhou (54275)

Peak abundances for the N-glycans which had the obvious overall changes among control subjects, moderate and severe LCMM subjects. by Jie Chen (5892)

Imiquimod decreases DFTD cell number in culture in a concentration and time dependent manner. by Amanda L. Patchett (3391931)

Mycolactone induces a decrease in dermal collagen fibers. by José B. Gama (296675)

Prior cafeteria diet feeding transiently reduced sucrose drinking and chow intake. by Jason B. Cook (4404970)

Comparison of ∑PCDD/F, PCDD/F TEQ, ∑PCB, PCB TEQ and ∑TEQ concentrations in eggs analyzed in this study and other relevant studies (pg/g ww except for ∑PCB ng/g ww, geometric mean... by Matti Viluksela (321291)

SP-D treatment results in a decrease in infectivity. by Kelly A. Soltysiak (795758)

Suppression does not depend on a growth rate decrease. by Laurent Jannière (28755)

MPN fusion expression causes a decrease in ciliogenesis. by Joanna Y. Lee (388303)

PDE-5 inhibition with sildenafil decreases the amount of dipropylenetriamine NONOate (DPTA-NO) necessary to prevent ECM. by Yuri C. Martins (333396)

Api5 depletion induces cell accumulation in G1 phase and decreases cell proliferation. by Marina Garcia-Jove Navarro (442768)

Decreased diaphragm muscle lateral bifurcations in GAD67-deficient (−/−) E15.5 mice. by Matthew J. Fogarty (283288)

“…<b>D</b> shows a significantly decreased lateral bifurcation number but not medial bifurcation (mean ± SEM) in GAD67-deficient mice compared to wild type (<i>n</i> = 5, *<i>P</i><0.05, unpaired <i>t</i> test). …”