Developmental delay of <i>rpS13/+</i> animals is not due to a decrease in ribosome numbers or reduced translation rates. by Lisa Patricia Deliu (13570709)

Plasma from ATTR individuals presents a higher proteolytic activity. by Gonçalo da Costa (198731)

ΔCCR5 transplant decreases tissue viral reservoirs in stably suppressed animals. by Christopher W. Peterson (242655)

Identification of small molecules that inhibit viral M mRNA nuclear export and/or decrease viral M mRNA levels. by Matthew Esparza (8661219)

“…<p>(<b>A</b>) Representative images showing uninfected cells; cells infected with A/WSN/33 and pretreated with 0.5% DMSO (control), which show viral M mRNA exported into the cytoplasm, in red; and cells infected with A/WSN/33 pre-treated with 2.5 μM of the transcription inhibitor DRB (5,6-dichloro-1-β-D-ribofuranosylbenzimidazole). …”

SARS-CoV-2 decreases excitatory synapses, while influenza A does not induce cell death in BCO. by Pinar Mesci (14053895)

mGluR5 receptor decreased glycinergic currents. by Zi-Yang Zhang (4988555)

“…<p>(<b>A–B</b>) Bath perfusion of DHPG for 3 min reduced GlyR-IPSCs (<b>A</b>; 70.2 ± 4.2% of baseline at 15–20 min post-DHPG, <i>t</i>[16] = 6.707, <i>p</i> < 0.001, paired Student <i>t</i> test), but not GABA_A-receptor–mediated IPSCs (<b>B</b>; 102.9 ± 3.3% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 0.347, <i>p</i> = 0.743) in spinal slices of mice. …”

Decreased microglial activation in TREM2-KO mice after stroke. by Matthias W. Sieber (106521)

Transfer of RSV-infected <i>Kdm5b</i>-deficient DCs leads to a decreased pathogenic pulmonary RSV challenge. by Catherine Ptaschinski (756139)

Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant. by Esther Magdalena Marquez-Lona (4183126)

“…<p>(A) Lysates from strains in stationary phase (A₆₀₀>5.0) were subjected to native gel electrophoresis followed by an in-gel activity assay with the fluorogenic proteasome substrate Suc-LLVY-AMC. …”

Impairment of autophagy decreases trimethylation at H3K4 in human monocytes. by Kathrin Buffen (651914)

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Simulated effects of increased pCREB combined with decreased pCaMKIIα on time courses of molecular pathways and synaptic weight W after IA training. by Yili Zhang (540283)

“…The light blue area represents W less than 200% of basal level. (B) Example of dynamics of BDNF protein/mRNA (B1-2), C/EBPβ protein (B3), pCREB (B4), pCaMKIIα (B5), Sin3a binding (B6), MeCP2 binding (B7), HDAC2 binding (B8), and W (B9), with the standard parameter values in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010239#pcbi.1010239.t001" target="_blank">Table 1</a> (black dashed) or with <i>k</i>_{<i>basalp_creb</i>} increased by ~50% and <i>k</i>_{<i>basalp_CaMKII</i>} decreased by ~50% from control combined with higher binding levels of MeCP2, Sin3a and HDAC2 (blue) to simulate IA conditioning in infant rats. …”

Targeted point mutation (F639A) in the GluN1 subunit decreases ethanol sensitivity of NMDA receptors. by Carolina R. den Hartog (484817)

Reduction of GC B cells decreases the number of Tfh cells in NZB/W F1 mice. by Isharat Yusuf (354734)

Structure model predictions of wildtype and A398E/V and M1425V/I Ca_V3.3 channels. by Yousra El Ghaleb (22075892)

Subjects:

Data_Sheet_1_The Risky Decrease of Fishing Reference Points Under Climate Change.docx by Morgane Travers-Trolet (548023)

“…The model was first parameterized and run to fit the historical situation (2000–2009) and then used to assess the ecosystem state for the 2050–2059 period, using two contrasting climate change scenarios (RCP 4.5 and RCP 8.5). For each condition, a monospecific MSY estimation routine was performed by varying species fishing mortality independently and allowed estimation of reference points for each species. …”

All data points from Fig 5. by Sara Hijazi (21656615)

“…Following a remyelination period of 5 weeks, PV interneuron properties were only partially recovered, suggesting that transient juvenile demyelination leads to long-lasting impairments of PV interneuron function. …”

BECN1 knockdown and BCL-W/BCL2 co-inhibition decreases cell proliferation through increased apoptosis in resistant cells. by Anatasha C. Crawford (255140)

Tetrandrine decreases Mtb antigen presentation. by Elham Karamooz (2584474)