Prolonged treatment with oxytocin does not decrease the neural stem cell pool. by Arvind Palanisamy (3159156)

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

mTOR inhibition decreased mitochondrial mass. by Piero Dalle Pezze (622889)

“…(B) The model prediction was confirmed by measuring mitochondrial mass using mitotracker green and quantifying the fluorescence intensities (n = 3). Exogenous addition of 10 nM Torin1 significantly decreased the average mass (Mann-Whitney test, * P<0.05) <i>in vitro</i>. …”

miR-105 results in decreased Cdk6 expression at both the mRNA and protein levels. by D. Rice Honeywell (442714)

“…Blots were reprobed for levels of β-actin as a loading control for total protein. We observed a significant decrease in both Cdk6 mRNA and protein expression in miR-105 overexpressing as compared to control mimic-transfected PC3 cells. …”

Top k-NN clusters of metabolites decreased at 4 hours. by Zarazuela Zolkipli-Cunningham (5234186)

Top k-NN cluster of metabolites decreased at 30 minutes. by Zarazuela Zolkipli-Cunningham (5234186)

LPS dose-dependently decreases T cell proliferative response to OKT3. by Fanny Poujol (834338)

Decreased nephrin expression. by Sandra Müller-Krebs (485766)

No significant sex differences in Iso-induced decrease of CaD₈₀. by Gregory S. Hoeker (650231)

“…B) Summary data for the decrease in CaD₈₀ (versus baseline values) as a function of the dose of Iso (1, 10, 31.6, 100, 316.2 nM) in the LV base <i>(left)</i> and apex <i>(right)</i> with pacing at 3 (<i>top</i>) and 5.5 Hz (<i>bottom</i>) for female (n = 5) and male (n = 5) hearts. …”

Table 2_Increased frequencies of human Th-17 CD4+ T-cells and decreased T-regulatory cells in patients with early and advanced metabolic dysfunction-associated steatotic liver dise... by Elżbieta Supruniuk (16736637)

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function by Cheryl Hemingway (4594654)

“…Findings were validated in a second cohort with concordance of the direction of differential expression in both TBM (r² = 0.78 p = 2x10^-16) and PTB patients (r² = 0.71 p = 2x10^-16) when compared to a second group of healthy controls. …”

Observed decreases in capacity. by Robert L. Burdett (17364685)

Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation by Baoqiang Li (1610221)

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction by Jin Chai (183630)

“…The levels of membrane transporters, OSTβ and OCT1, were increased 10.4-fold and 1.8-fold, respectively, (<i>p</i><0.05), whereas those of OSTα, ABCG2 and ABCG8 were all decreased by approximately 40%, (<i>p</i><0.05) in human cholestatic livers. …”

F-actin decreases after M64HCl treatment in Caco-2 cells. by Sema Oncel (10152053)

Subjects:

A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

“…In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”