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721
Phytochemicals as Micronutrients: What Is their Therapeutic Promise in the Management of Traumatic Brain Injury?
Published 2022“…In this regards, phytochemicals have been acknowledged to cause a significant decrease in neuronal injury through different mechanisms including the activation of the Nrf2 transcription factor leading to activation of several antioxidant enzyme systems such as superoxide dismutase, inhibition of NADPH oxidases (NOX) enzymes, suppression of nuclear factor kappa B (NF-κB) activity and reduction of the release of inflammatory mediators, suppression of the NLRP3 inflammasome, stimulation of neurogenesis by activating neurotrophic factors (BDNF), among others. …”
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722
Adrenoceptor Desensitization: Current Understanding of Mechanisms
Published 2024“…Without tightly controlled desensitization of these receptors, homeostatic imbalance may ensue, thus precipitating various diseases. Here, we critically appraise the mechanisms implicated in adrenoceptor desensitization. …”
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723
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724
Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells
Published 2014“…The optimum concentration, 0.2 mg/ml, significantly decreased HASMCs viability at 24 and 72 hours by 52.5 ± 10.39% and 47.6 ± 9.83% compared to control, respectively. …”
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725
Nanosilver loaded GelMA hydrogel for antimicrobial coating of biomedical implants
Published 2015“…Different strategies have been developed to decrease the incidence of bacterial infections related medical devices failure. …”
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726
Obesity-induced changes in kidney mitochondria and endoplasmic reticulum in the presence or absence of leptin
Published 2015“…We compared two normotensive genetic mouse models of obesity, leptin-deficient ob/ob mice and hyperleptinemic melanocortin-4 receptor-deficient mice (LoxTB MC4R−/−), with their respective lean controls. …”
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727
Association between antioxidant metabolites and N-terminal fragment brain natriuretic peptides in insulin-resistant individuals.
Published 2024“…Moreover, we revealed notable associations between NT-proBNP levels and antioxidant metabolic pathways, particularly those related to glutathione metabolism, in insulin-resistant, but not insulin-sensitive individuals. The significant decrease in NT-proBNP observed in individuals with insulin resistance may be attributed to a direct or indirect enhancement in glutathione production, which is regarded as a compensatory mechanism against oxidative stress. …”
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728
Flight Scheduling in the Airspace
Published 2016“…To deal with this problem, we propose a mixed integer programming formulation to find a flight plan that minimizes the objective function, while ensuring the FAA safety standards. …”
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729
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries
Published 2022“…Methods: Using pharmaceutical sales data from the IQVIA-multinational integrated data analysis system database, we assessed use of systemic antifungal agents in humans in 27 middle- and 38 high-income countries from 2008 through 2018. …”
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730
Prevention of oral cancer
Published 2017“…This chapter will address and focus on the aforementioned prevention strategies, elaborating and expanding on risk factors and how to decrease chances of developing oral cancer. Additionally we will look at barriers against prevention developing an intricate and complete picture of the links between methods of prevention and factors that hinder prevention. …”
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731
Pd nanocrystals encapsulated in MOF-derived Ni/N-doped hollow carbon nanosheets for efficient thermal CO oxidation: unveiling the effect of porosity
Published 2023“…The obtained Pd/Ni-MOF-HNC possesses hollow carbon sheets with a great surface area (153.05 m2 g−1), pore volume (0.12 cm3 g−1), rich Pd/Ni-Nx active sites, Ni-metal defects, rich N-content (7.53 at%), mixed Pd/Ni-oxide phases, and uniformly distributed ultra-small Pd nanocrystals (7.03 ± 1.10 nm); meanwhile, Pd/Ni-MOF-NC formed without etching had no porosity and less Ni-metal defects. …”
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732
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733
Energy Demand Estimation and Forecasting in Qatar
Published 2018“…He consider three scenarios, the reference one and two alternatives with increases/decreases in the factors affecting energy demand. …”
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734
The Effect of Hyperoxia on Central and Peripheral Factors of Arm Flexor Muscles Fatigue Following Maximal Ergometer Rowing in Men
Published 2022“…The MCA Vmean increased by 38% (p < 0.05) with hyperoxia, while only marginally increased with normoxia. Similarly, ScO2 was not affected with hyperoxia but decreased by 7.0 ± 4.8% from rest (p = 0.04) with normoxia. …”
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735
Smoking cessation counseling in Qatar: Community pharmacists' attitudes, role perceptions and practices
Published 2012“…Results: Over 5 months, we collected 127 surveys (40 % response rate). Only 21 % of respondents reported that they always or most of the time asked their patients if they smoke. …”
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736
Ethanolic extract of Origanum syriacum L. leaves exhibits potent anti-breast cancer potential and robust antioxidant properties
Published 2022“…Protein levels of markers of apoptosis (BCL-2, pro-Caspase3, p53), proliferation (p21, Ki67), cell migration, invasion, or adhesion (FAK, E-cadherin), angiogenesis (iNOS), and cell signaling (STAT3, p38) were determined by immunoblotting. …”
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737
Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…The expected changes in macroclimate and N deposition at the global scale by the end of this century are estimated to increase the 12-month mass loss of easily decomposable litter by 1.1-3.5% and of the more stable substrates by 3.8-10.6%, relative to current mass loss. In contrast, expected changes in atmospheric N deposition will decrease the mid-term mass loss of high-quality litter by 1.4-2.2% and that of low-quality litter by 0.9-1.5% in the temperate biome. …”
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738
Heterogeneous Diplomacy of Political Relations between Iran and Afghanistan in exploiting the water of Helmand Border River
Published 2024“…It has always influenced the relations between the two countries since the border formation. The fluctuation of the Helmand water flow and decrease in the running water towards Sistan (Iran) in the last hundred years has always created problems in relations between Iran and Afghanistan at the National and local levels. …”
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739
Contrasting cardiovascular mortality trends in Eastern Mediterranean populations: Contributions from risk factor changes and treatments
Published 2016“…Results Risk factor trends: Smoking prevalence was high in men, persisting in Syria but decreasing in Tunisia, oPt and Turkey. BMI rose by 1-2 kg/m2 and diabetes prevalence increased by 40%-50%. …”
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740
Wireless Car Control Over the Cellular System
Published 2016“…This project establishes two ways of communications; from the robot to the user showing the video content and status about the scenario. …”
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