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Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction
Published 2017“…Aims: Circulating microparticles (MPs) from metabolic syndrome patients and those generated from apoptotic T-cells induce endothelial dysfunction; however, the molecular and cellular mechanism(s) underlying in the effects of MPs remain to be elucidated. Results: Here, we show that both types of MPs increased expression of endoplasmic reticulum (ER) stress markers XBP-1, p-eIF2alpha and CHOP and nuclear translocation of ATF6 on human aortic endothelial cells. …”
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1264
Investigation Into the Effects of Non-Linear Loading of Domestic Power Network on Home Appliances
Published 2016“…Now we have two controlled rectifier connected to the same ac supply. …”
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1265
Gravitohydrodynamic Instability Of A Streaming Fluid Cylinder
Published 1996“…As the fluid is axially streaming we have used the macroscopic perturbation technique of small increments. …”
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1266
Location privacy preservation in secure crowdsourcing-based cooperative spectrum sensing
Published 2016“…However, cooperative sensing is also facing some series of security threats. In this paper, we focus on two major problems. The first problem is the localization preservation of the secondary users. …”
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1267
Profiling of the Differentially Expressed Genes of Inflammation and Angiogenesis of Human Brain Microvascular Endothelial Cells Evoked by Cell Injury In-Vitro to Mimic Acute Ischem...
Published 2020“…Acute IS (AIS) injury of PHBMEC is not well characterized in terms of its consequences on cell functions using genomic function profiling. In our study, we aimed to establish a new model of an acute in-vitro ischemic stroke, within a time limit of 2 hrs., with depriving whole nutrients and not just glucose, under hypoxic condition, in a model we created as oxygen nutrients deprivation (OND). …”
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1268
Methylmercury, Trace Metals, Organotins and Their Effects on the Qatari Mangrove Shrimp, Palaemon khori
Published 2022“…The Qatari mangroves of Al-Khor are being increasingly exposed to a wide variety of anthropogenic pollutants due to land reclamation and urban expansion. In this study, we evaluated the lethal and genotoxic effects of methylmercury, trace metals, and organotins, assessing mortality and aneuploidy levels (abnormal number of chromosomes) in the endemic shrimp Palaemon khori under laboratory conditions. …”
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1269
Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome.
Published 2021“…Eight pro-coagulation proteins were elevated in PCOS: plasminogen activator inhibitor-1 (p < 0.0001), fibrinogen (p < 0.01), fibrinogen gamma chain (p < 0.0001), fibronectin (p < 0.01), von Willebrand factor (p < 0.05), D-dimer (p < 0.0001), P-selectin (p < 0.05), and plasma kallikrein (p < 0.001). However, two anticoagulant proteins, vitamin K-dependent protein-S (p < 0.0001) and heparin cofactor-II (p < 0.001) were elevated and prothrombin was decreased (p < 0.05). …”
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1270
The impacts of water level fluctuations from paddy fields and aquaculture ponds on wetland habitats for wintering waterbirds: Implications for wetland management
Published 2022“…Based on remote sensing image data and hydrological data, we selected Caizi Lake as a study site and comparatively analyzed the changes in wintering waterbird habitats in a water level sequence under the two scenarios. …”
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1271
Novel Isosteviol Derivatives Induced Apoptosis In Human Lung Cancer
Published 2014“…Cancer metastasis is the major cause of cancer death. We previously reported novel isosteviols derivatives which induced cytotoxicity in lung cancer cells. …”
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1272
Dynamic Distributed Multi-Path Aided Load Balancing for Optical Data Center Networks
Published 2022“…The simulation results show that our proposed algorithm reduces the TOR-to-TOR latency by 15.88% and decreases the packet loss by 22.06% compared to conventional algorithms under regular load conditions, which effectively improves the overall performance of the Hoe-DCNs. …”
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Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
Published 2016“…Results show that cell viability decreased to 93 ± 3%, 83 ± 6%, 65 ± 4% and 39 ± 3% at 10, 25, 50 and 100 mM of glucose on day 1 with further drastic decrease in cell viability to 73 ± 5%, 61 ± 3%, 35 ± 2%, and 11 ± 6%, respectively, on day 4 compared to the untreated cell. …”
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1275
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
Published 2020“…In order to investigate the inhibitory mechanisms of these two compounds towards fibril formation, we demonstrated that salvianolic acid B binds predominantly to monomers, while dihydromyricetin binds to oligomeric species and to a lower extent to monomers. …”
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Molecular and Structural Changes in Induced-Brain Stroke Tissue Using FTIR Imaging Spectroscopy, Scanning Electron and Atomic Force Microscopy
Published 2016“…All the samples were viewed with a FEI Quanta 200, USA scanning electron microscope at 10 kV. …”
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1278
NADPH-derived ROS generation drives fibrosis and endothelial-to-mesenchymal transition in systemic sclerosis: Potential cross talk with circulating miRNAs
Published 2022“…Although the etiopathology of this disease is largely unknown, endothelial damage and oxidative stress appear implicated in its initiation and maintenance. Here, we show for the first time that circulating factors present in SSc sera increased reactive oxygen species (ROS) production, collagen synthesis, and proliferation of human pulmonary microvascular endothelial cells (HPMECs). …”
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Conversion of Organic Municipal Wastes into Biochars and their Effect on Fertility Parameters of Normal and Sabkha Soils of Qatar
Published 2016“…Box-Behnken experimental design was used instead of the full factorial to decrease the number of treatments to a manageable level (126 treatments) with three replications at the center. …”
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1280