بدائل البحث:
we decrease » _ decrease (توسيع البحث)
nn decrease » _ decrease (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
2 we » _ we (توسيع البحث), 2 de (توسيع البحث), 2 e (توسيع البحث)
we decrease » _ decrease (توسيع البحث)
nn decrease » _ decrease (توسيع البحث)
a decrease » _ decrease (توسيع البحث), _ decreased (توسيع البحث), _ decreases (توسيع البحث)
2 we » _ we (توسيع البحث), 2 de (توسيع البحث), 2 e (توسيع البحث)
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841
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842
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
منشور في 2019"…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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احصل على النص الكامل
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843
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844
EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS
منشور في 2016"…Methodology: In the present study, utilizing the HRMEC, we evaluated the effect of high glucose (30mM) on several ER stress signaling pathway genes (HSPA5, EIF2K3, and XBP1) at the mRNA expression level; the inflammatory cytokines (NFkB) at the mRNA level; the adhesion molecules (ICAM-1 and P-selectin) by flow cytometry. …"
احصل على النص الكامل
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845
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846
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847
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848
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849
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850
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851
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852
Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
منشور في 2023"…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …"
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احصل على النص الكامل
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853
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854
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855
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856
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857
Enhancing the production of biogas through anaerobic co-digestion of agricultural waste and chemical pre-treatments
منشور في 2020"…The results revealed that the highest cumulative methane production (CMP) of 297.99 NL/kgVS can be generated by co-digestion of ASWs and CD at a ratio of 60:40. Further improvement was achieved via alkalinity treatment with 1.0 g of NaHCO3/gVS leading to decrease in lignin, cellulose, and hemicellulose contents of feedstock by 3.5%, 10.5% and 15.9%, respectively, converting them to soluble fractions and improving the CMP by 11.2–29.7% based on substrate quality. …"
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858
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859
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
منشور في 2024"…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …"
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احصل على النص الكامل
احصل على النص الكامل
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860