يعرض 841 - 860 نتائج من 1,773 نتيجة بحث عن '(( 2 we decrease ) OR ( 10 ((peter decrease) OR (((nn decrease) OR (a decrease)))) ))', وقت الاستعلام: 0.30s تنقيح النتائج
  1. 841
  2. 842

    Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling حسب Chung, Jihyun

    منشور في 2019
    "…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …"
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  3. 843
  4. 844

    EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS حسب Saif, Atiya Ramadan

    منشور في 2016
    "…Methodology: In the present study, utilizing the HRMEC, we evaluated the effect of high glucose (30mM) on several ER stress signaling pathway genes (HSPA5, EIF2K3, and XBP1) at the mRNA expression level; the inflammatory cytokines (NFkB) at the mRNA level; the adhesion molecules (ICAM-1 and P-selectin) by flow cytometry. …"
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  5. 845
  6. 846
  7. 847
  8. 848
  9. 849
  10. 850
  11. 851
  12. 852

    Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus حسب Dimitrios, Patoulias

    منشور في 2023
    "…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …"
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  13. 853
  14. 854
  15. 855
  16. 856
  17. 857

    Enhancing the production of biogas through anaerobic co-digestion of agricultural waste and chemical pre-treatments حسب Almomani F.

    منشور في 2020
    "…The results revealed that the highest cumulative methane production (CMP) of 297.99 NL/kgVS can be generated by co-digestion of ASWs and CD at a ratio of 60:40. Further improvement was achieved via alkalinity treatment with 1.0 g of NaHCO3/gVS leading to decrease in lignin, cellulose, and hemicellulose contents of feedstock by 3.5%, 10.5% and 15.9%, respectively, converting them to soluble fractions and improving the CMP by 11.2–29.7% based on substrate quality. …"
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  18. 858
  19. 859

    Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function حسب Da'as, Sahar I.

    منشور في 2024
    "…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …"
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  20. 860