Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. حسب P, Sneha

"…Galactosemia type 2 is an autosomal recessive disorder characterized by the deficiency of galactokinase (GALK) enzyme due to missense mutations in GALK1 gene, which is associated with various manifestations such as hyper galactosemia and formation of cataracts. …"
احصل على النص الكامل
احصل على النص الكامل

Understanding the progress and challenges in the fields of thermo-catalysis and electro-catalysis for the CO2 conversion to fuels حسب Yadav, V. S. K.

"…Several studies have been reported in both the processes with a desire to decrease the atmospheric CO2 concentration by stopping CO2 emissions at the site of generation itself. …"
احصل على النص الكامل
احصل على النص الكامل

The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis حسب Kheraldine, Hadeel

"…In this study, we explored the anti-cancer effects of different generations and surface chemistries of PAMAMs on HER2-positive breast cancer cell lines. …"
احصل على النص الكامل

Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate حسب Nazir, Roshan

"…Herein we report a catalyst consisting of CuAg/Cu2O nanoparticles (NPs), synthesized on the two-dimensional carbon nitride (CN) surface via galvanic exchange route for electrocatalytic methanol oxidation and carbon dioxide reduction. …"
احصل على النص الكامل
احصل على النص الكامل

Fabrication of Selective Sensors for Hg2+ Traces in Water Using Graphene Decorated with Metal Nanoclusters حسب Ayesh, Ahmad I.

"…The system consists of three main chambers (source, mass filter, and deposition chambers) that were pumped initially to a base pressure of 10-8 mbar using two turbo pumps. …"
احصل على النص الكامل
احصل على النص الكامل

Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events حسب Raj, K. Diraviya

"…We used a 12-yr data set of benthic cover (2005�2017), spanning two bleaching events, to assess changes in benthic cover and coral community composition along 21 islands within Gulf of Mannar (GoM), southeast India. …"
احصل على النص الكامل
احصل على النص الكامل

Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. حسب Seidel, Monika

"…We also show that the RyR2 N-terminus domain interacts with the C-terminal channel pore region in a Ca2+-independent manner. …"
احصل على النص الكامل
احصل على النص الكامل

Reinfections in COVID-19 Patients: Impact of Virus Genetic Variability and Host Immunity حسب Fakhroo, Aisha

"…In this review, we discuss SARS-CoV-2 reinfection rates in previously infected and vaccinated individuals in relation to humoral responses. …"
احصل على النص الكامل
احصل على النص الكامل

Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria حسب Al-Sadeq, Duaa W.

"…In this study, we present the clinical and biochemical characterization of two novel CBS missense mutations that do not respond to pyridoxine treatment, namely c.689T > A (L230Q) and 215A > T (K72I), identified in a Chinese patient. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Enhancement of Ethanol Production in Electrochemical Cell by Saccharomyces cerevisiae (CDBT2) and Wickerhamomyces anomalus (CDBT7) حسب Joshi J.

"…In that regard, in the present study, we have used two highly efficient ethanol producing yeast strains, viz., Saccharomyces cerevisiae (CDBT2) and Wickerhamomyces anomalous (CDBT7), in an electrochemical cell to enhance ethanol production. …"
احصل على النص الكامل
احصل على النص الكامل

Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome. حسب Thirumal Kumar, D

"…In the simulations, we observed decreased deviation and fluctuations in native NOD2, whereas decreased compactness and inter- and intramolecular hydrogen bonds were observed in the W490L mutant. …"
احصل على النص الكامل
احصل على النص الكامل

Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress حسب Fatima, Munazza T

"…We found that SESN2 silencing, though did not specifically induce ER stress, it aggravated the effects of thapsigargin-induced ER stress on oxidative stress and cell survival. …"
احصل على النص الكامل
احصل على النص الكامل

Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H2S: DFT study حسب Salih, Ehab

"…In this work, we present a highly sensitive gas sensor for the detection of poisonous hydrogen sulfide gas (H2S) based on copper and zinc co-doped zigzag graphene nanoribbon (Cu/Zn-ZGNR). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes. حسب Al-Asmakh, Maha

"…In this study, we have investigated the effect of oxygen tension on fetal membrane biology, as a reconsideration of the literature suggests that fetal membranes are normally exposed to approximately 3% O(2) (approximately 20 mmHg) in vivo, rather than the 20% O(2) (150 mmHg) used for in vitro culture. …"
احصل على النص الكامل
احصل على النص الكامل

Micromodel Study on Colloid Retention and Mobilization under different Geo-Chemical Conditions during Single and Two-Phase Flow حسب Nishad, Safna

"…Micromodels are analogs to porous media that allow the real-time visualization of pore-scale processes that occur at highly controllable physio-chemical conditions in the laboratory scale. In this thesis, we used a glass micromodel with representative geometry to observe the pore-scale mechanisms during colloid retention and mobilization experiments in a saturated and unsaturated porous media. …"
احصل على النص الكامل

Conjugated Linoleic Acid (CLA) co-treatment alleviates antidiabetic drug, rosiglitazone associated deterioration of bone remodeling حسب Ibrahim, Khadega

"…Diabetes mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia due to decreased insulin secretion, defective action or both. …"
احصل على النص الكامل
احصل على النص الكامل

Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes حسب Abushanab, Dina

"…AimsInsufficient risk factor control can lead to a loss of millions of productivity-adjusted life years (PALYs). We aimed to assess the productivity burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) and examine the potential advantages of enhancing the control of modifiable CVD risk factors in Qatar. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Aqueous Extract Of Origanum Syriacum Inhibits Proliferation, Migration, Adhesion As Well As Erk1/2 Phosphorylation In Aggressive Breast Cancer حسب Al Kahlout, Amal

"…Moreover, preliminary results indicate that OSE decreased ERK1/2 phosphorylation in MDA-MB-231 cells. …"
احصل على النص الكامل
احصل على النص الكامل

Work-from-home, electricity, and water: Evidence from COVID-19 in Qatar حسب Bernstein, David H.

احصل على النص الكامل
احصل على النص الكامل

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling. حسب Akhtar, Sabah

"…SNG treatment of MM cells leads to down-regulation of the anti-apoptotic proteins including cyclin D, Bcl-2, Bclxl, and XIAP. In addition, it also upregulates pro-apoptotic protein, Bax. …"
احصل على النص الكامل
احصل على النص الكامل