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EFFECT OF ENDOPLASMIC RETICULUM STRESS MEDIATED BY HYPERGLYCEMIA ON BARRIER FUNCTION IN RETINAL CELLS
Published 2016“…Methodology: In the present study, utilizing the HRMEC, we evaluated the effect of high glucose (30mM) on several ER stress signaling pathway genes (HSPA5, EIF2K3, and XBP1) at the mRNA expression level; the inflammatory cytokines (NFkB) at the mRNA level; the adhesion molecules (ICAM-1 and P-selectin) by flow cytometry. …”
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343
Centrifugal Compressor Spiral Dry Gas Seal Simulation Working at Reverse Rotation
Published 2013“…The open force corresponding to reverse rotation increased with a value 1.5kN for both the 100 overlap and 50% forward overlap seal faces, but using seal face with 50% backward overlap failed to enhance the open force at reversal condition.…”
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344
Thermochemical splitting of CO2 using solution combustion synthesized lanthanum-strontium-anganese perovskites
Published 2021“…Redox reactivity of La(1-x)SrxMnO3 (LSM) perovskites towards a solar thermochemical CO2 splitting (CS) cycle is investigated. …”
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345
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…Furthermore, circular dichroism spectroscopy experiments using recombinant CaM proteins reveals a decreased structural stability of the four mutants compared to the wild-type CaM protein in the presence of Ca2+. …”
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Effect of electroless bath composition on the mechanical, chemical, and electrochemical properties of new NiP-C 3 N 4 nanocomposite coatings
Published 2019“…The results indicated that the alkaline electroless bath produced a NiP–C3N4 NCC with a microhardness 250 HV200 higher than that produced from the acidic one. …”
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349
A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats
Published 2022“…After enzyme treatment, simmondsin content decreased from 33.0 % to 3.0 % and glucose content increased from 16.2 % to 27.3 % reflecting simmondsin hydrolysis. …”
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350
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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351
Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway
Published 2017“…Pretreatment of endothelium-intact rings with L-NAME (a non-selective inhibitor of nitric oxide synthase, 100 µM), or ODQ (an inhibitor of soluble guanylyl cyclase, 10 µM) significantly diminished SF-mediated vasorelaxation. …”
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The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio...
Published 2016“…This was followed by phase-2 of uncontrolled hemorrhage as induced by transection of the splenic parenchyma at the two ends of the organ and severing one of the branches of the splenic artery. …”
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Effect of reinforcement concentration on the properties of hot extruded Al-Al2O3 composites synthesized through microwave sintering process
Published 2017“…Results showed that, as the content of hard ceramic particles increases, it improves overall mechanical properties including microhardness, 0.2% yield strength, ultimate compression/tensile strength, and Young's modulus while the ductility and co-efficient of thermal expansion decreases. XRD patterns and SEM/EDS mapping images show a uniform distribution of Al2O3 particles in the Al matrix. …”
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Vascular access types in hemodialysis patients in palestine and factors affecting their distribution: A cross-sectional study
Published 2019“…We also highly recommend decreasing the duration of temporary catheters. …”
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358
A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation...
Published 2019“…Among these 19 compounds, Akti-1/2 exhibited the best binding affinity with both native AKT1 and the E17K mutant. …”
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359
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
Published 2018“…Among all the EBV genes, most of the recent investigations focused on studying the LMP-1 oncogene because of its high degree of polymorphism and association with tumorigenic activity. There are two main EBV genotypes, Type 1 and 2, distinguished by the differences in the EBNA-2 gene. …”
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360
Estimation of Mechanical Properties of Copper Powder Filled Linear Low-Density Polyethylene Composites
Published 2022“…Conclusion: In line with the experimental data, we found that as we increased the volume fraction of the copper powder, the elongation and stress at break of the composites decreased, while the Young’s modulus increased.…”
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