Annexin A1 and A2: Roles in Retrograde Trafficking of Shiga Toxin by Lionel Tcatchoff (152994)

“…<div><p>Annexins constitute a family of calcium and membrane binding proteins. As annexin A1 and A2 have previously been linked to various membrane trafficking events, we initiated this study to investigate the role of these annexins in the uptake and intracellular transport of the bacterial Shiga toxin (Stx) and the plant toxin ricin. …”

Image_2_Characterizing Different Strategies for Resolving Approach-Avoidance Conflict.TIF by Hector Bravo-Rivera (383055)

“…The immediate early gene cFos revealed that Timers showed increased activity in the ventral striatum and midline thalamus relative to the other two subgroups, Avoidance-preferring rats showed increased activity in the amygdala, and Approach-preferring rats showed decreased activity in the prefrontal cortex. …”

Dmp1α Inhibits HER2/neu-Induced Mammary Tumorigenesis by Elizabeth A. Fry (477763)

“…To directly demonstrate the role of Dmp1 in preventing HER2/neu-driven oncogenic transformation, we established <i>Flag-Dmp1α</i> transgenic mice (<i>MDTG</i>) under the control of the mouse mammary tumor virus (<i>MMTV</i>) promoter. …”

Image_4_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.jpeg by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

CREB Inhibits AP-2α Expression to Regulate the Malignant Phenotype of Melanoma by Vladislava O. Melnikova (242902)

“…</p><h3>Methodology/Principal Findings</h3><p>Herein, we demonstrate that both inhibition of PKA-dependent CREB phosphorylation, as well as silencing of CREB expression by shRNA, restored AP-2α protein expression in two metastatic melanoma cell lines. …”

Table_6_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.xlsx by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Table_2_Gut Microbiota in Tibetan Herdsmen Reflects the Degree of Urbanization.PDF by Huan Li (120482)

DataSheet_2_Variations in genetic diversity in cultivated Pistacia chinensis.pdf by Biao Han (4388584)

“…Population structure analysis based on the nuclear SNPs showed two groups, clearly clustered together, and more than a third of the total individuals were classified as hybrids. …”

Table_1_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.xlsx by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Image_2_Wheat Intercropping Enhances the Resistance of Watermelon to Fusarium Wilt.JPEG by Huifang Lv (5280581)

Image_5_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.tif by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Table_4_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.xlsx by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Presentation_2_The Function of Autophagy in Lace Plant Programmed Cell Death.pptx by Adrian N. Dauphinee (7523651)

Table_3_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.xlsx by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Table_5_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.xlsx by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Image_1_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.jpeg by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Image_3_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.jpeg by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”

Table 2_Sulforaphane acutely activates multiple starvation response pathways.xlsx by Kendra S. Plafker (2379379)

“…SFN treatment (i) increased mitochondrial mass and resistance to oxidative stress, (ii) acutely suppressed markers of mTORC1/2 activity via inhibition of insulin signaling, (iii) upregulated autophagy and further amplified autophagic flux induced by rapamycin or nutrient deprivation while concomitantly promoting lysosomal biogenesis, and (iv) acutely decreased glucose uptake and lactate secretion followed by an adaptive rebound that coincided with suppressed protein levels of thioredoxin-interacting protein (TXNIP) due to early transcriptional down-regulation. …”

Identification of Novel GTP Analogs as Potent and Specific Reversible Inhibitors for Transglutaminase 2 by Lakshmi P. Kolligundla (13815199)

“…Although guanine nucleotide (GTP) could inhibit TG2, its inhibitory activity decreased with increased calcium concentration. …”

Table_7_Global landscape of 2-hydroxyisobutyrylation in human pancreatic cancer.xlsx by Yun Lu (210518)

“…However, the role of K_hib proteins remains to be investigated. Here, we firstly identified 10,367 K_hib sites on 2,325 modified proteins in seven patients with pancreatic cancer by applying liquid chromatography with tandem mass spectrometry (LC-MS/MS) qualitative proteomics techniques. …”