Data_Sheet_1_The Angiotensin II Type 1 Receptor-Associated Protein Attenuates Angiotensin II-Mediated Inhibition of the Renal Outer Medullary Potassium Channel in Collecting Duct C... by Juliano Zequini Polidoro (10800534)

“…Experiments were performed in the presence of 10⁻¹⁰ M Ang II or vehicle for 40 min. We observed that Ang II-induced a significant inhibition of ROMK in LacZ, but not in ATRAP-overexpressed M-1 cells. …”

Experimental Test of Two Predictions of the Computer Simulation of the Early Events in TCR Signaling by Grégoire Altan-Bonnet (71882)

“…This timescale diverges in a nonlinear fashion when the number of agonist ligands is decreased. We then systematically measured the kinetics of the ppERK response of naïve OT-1 T cells upon activation with RMA-S APCs presenting different numbers of SIINFEKL-K^b (B) and derived the characteristic time of response using a generic sigmoidal fit. …”

<i>myh9</i> expression in the context of <i>apol1</i>/<i>APOL1</i> modulation. by Blair R. Anderson (765261)

“…(B) <i>APOL1</i> G2 expression results in a significant decrease in <i>myh9</i> expression compared to sham-injected control embryos, suggesting that the altered APOL1 protein may regulate <i>myh9 in vivo</i>. …”

The Potential of Class II Bacteriocins to Modify Gut Microbiota to Improve Host Health by Özgün C. O. Umu (3190212)

“…However, knowledge on bacteriocin producers <i>in situ</i> and their function in the gut of healthy animals is still limited. In this study, we investigated five bacteriocin-producing strains of LAB and their isogenic non-producing mutants for probiotic values. …”

Image2_A role for TRPC3 in mammalian testis development.jpg by Zhenhua Ming (5179547)

“…In this study, we describe a novel testicular target gene of SOX9, Trpc3. …”

Data_Sheet_1_MAGI2 Gene Region and Celiac Disease.ZIP by Amaia Jauregi-Miguel (8152479)

“…Silencing of lncRNA decreases the levels of MAGI2 protein. At the same time, silencing of MAGI2 affects the expression of several TJ-related genes. …”

Image_2_Alterations of the Fecal Microbiota in Chinese Patients With Multiple Sclerosis.tif by Zongxin Ling (155251)

“…The microbial diversity and composition, bacterial co-occurrence correlations, predictive functional profiles, and microbiota-cytokine correlations between the two groups were compared. We observed that while the overall structure of the fecal microbiota did not change significantly, the abundances of several key functional bacteria, primarily Faecalibacterium, decreased remarkably. …”

Table_2_The (Not So) Changing Man: Dynamic Gender Stereotypes in Sweden.DOCX by Marie Gustafsson Sendén (4842333)

“…Furthermore, participants estimated no change in gender stereotypes for the future, and they overestimated how often women and men occupy gender non-traditional roles at present. In Study 2, we controlled for participants’ actual knowledge about role change by either describing women’s increased responsibilities on the job market, or men’s increased responsibility at home (or provided no description). …”

Table_2_The (Not So) Changing Man: Dynamic Gender Stereotypes in Sweden.DOCX by Marie Gustafsson Sendén (4842333)

“…Furthermore, participants estimated no change in gender stereotypes for the future, and they overestimated how often women and men occupy gender non-traditional roles at present. In Study 2, we controlled for participants’ actual knowledge about role change by either describing women’s increased responsibilities on the job market, or men’s increased responsibility at home (or provided no description). …”

Image_2_CD38: an ecto-enzyme with functional diversity in T cells.jpeg by Alip Ghosh (127963)

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…The BCAA-restricted diet marginally lowered Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) levels: baseline 1.5 ± 0.2 to 1.0 ± 0.1; (p = 0.096).</p> <p>Conclusion: We successfully lowered circulating BCAAs by 50% while maintaining iso-nitrogenous, iso-caloric dietary intakes, and while meeting the recommended daily allowances (RDA) for protein requirements. …”

Image2_A role for TRPC3 in mammalian testis development.TIF by Zhenhua Ming (5179547)

“…In this study, we describe a novel testicular target gene of SOX9, Trpc3. …”

Table_3_Multimodal Neuroimaging in Rett Syndrome With MECP2 Mutation.pdf by Yu Kong (487122)

“…<p>Rett syndrome (RTT) is a rare neurodevelopmental disorder characterized by severe cognitive, social, and physical impairments resulting from de novo mutations in the X-chromosomal methyl-CpG binding protein gene 2 (MECP2). While there is still no cure for RTT, exploring up-to date neurofunctional diagnostic markers, discovering new potential therapeutic targets, and searching for novel drug efficacy evaluation indicators are fundamental. …”

Image_2_Integrated Analysis of Molybdenum Nutrition and Nitrate Metabolism in Strawberry.tif by Li Liu (75607)

“…As expected, NR activity was higher under sufficient MoO₄^2- levels. Furthermore, seedlings grown on Mo-deficient medium exhibited decreased ¹⁵NO₃^- translocation and lower ¹⁵NO₃^- use efficiency. …”

Table_2_Oral microbiome characteristics in patients with pediatric solid tumor.XLSX by Xichun Cui (7835390)

“…A meticulous screening process ensued, and conducted microbial MiSeq sequencing after screening.</p>Results<p>We documented the oral microbiome attributes among pediatric diagnosed with solid tumors (PST), and meanwhile, we observed a significant trend of decreased oral microbiota diversity in the pediatric solid tumor group. …”

Table_1_Multimodal Neuroimaging in Rett Syndrome With MECP2 Mutation.pdf by Yu Kong (487122)

“…<p>Rett syndrome (RTT) is a rare neurodevelopmental disorder characterized by severe cognitive, social, and physical impairments resulting from de novo mutations in the X-chromosomal methyl-CpG binding protein gene 2 (MECP2). While there is still no cure for RTT, exploring up-to date neurofunctional diagnostic markers, discovering new potential therapeutic targets, and searching for novel drug efficacy evaluation indicators are fundamental. …”

Developing a Copper(II) Isopropyl 2‑Pyridyl Ketone Thiosemicarbazone Compound Based on the IB Subdomain of Human Serum Albumin–Indomethacin Complex: Inhibiting Tumor Growth by Remo... by Xueyu Man (12996632)

“…We optimized a series of Cu(II) isopropyl 2-pyridyl ketone thiosemicarbazone compounds to obtain a Cu(II) compound (C4) with significant cytotoxicity and then constructed an HSA–IND–C4 complex (HSA–IND–C4) delivery system. …”

Inhibitory effect on other K⁺ channels. by Ancy Joseph (5634794)

“…The application of 100 μM ostruthin inhibited TASK-1 currents in a concentration-dependent manner (n = 10). …”

Image_2_Transcriptome Analysis Reveals the Mechanism of Natural Ovarian Ageing.jpeg by Lili Chen (66681)

“…Finally, the results of msviper found that transcription factors such as KDM1A, PRDM5, ZNF726, PPARG, FOXJ2, and GLI2 were mainly activated in the 20-29 years group, while VAV1, RUNX3, ZC3H12D, MYCL, and IRF5 were mainly activated in the 30-39 years group and that these transcription factor activities were diagnostic of natural ovarian ageing (AUC: 0.65-0.71).…”

Presentation_1_Impaired B-cell function in ERCC2 deficiency.pptx by Raphael Rossmanith (11855828)

“…</p>Results<p>We investigated three unrelated TTD1 patients who presented with recurrent infections early in life of whom two harbored novel ERCC2 mutations and the third patient is a carrier of previously described pathogenic ERCC2 mutations. …”