Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

Subjects:

Fig 5 - by Matthew C. Kochem (18476069)

“…Sensitivity to lactisole sweetness inhibition was correlated with decreased plasma glucose (R² = 0.84, p<0.01) when lactisole was added to the OGTT over the whole test (120 minute AUC). …”

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“…After the discovery of a mutation in the Janus kinase 2 (<i>JAK</i>2^V617F), JAK2 inhibitors have been tested as second-line therapies. …”

R346K Mutation in the <i>Mu</i> Variant of SARS-CoV‑2 Alters the Interactions with Monoclonal Antibodies from Class 2: A Free Energy Perturbation Study by Filip Fratev (1799740)

“…The <i>Mu</i> variant of SARS-CoV-2 has been recently classified as a variant of interest (VOI) by the World Health Organization (WHO) but limited data are available at the moment. …”

R346K Mutation in the <i>Mu</i> Variant of SARS-CoV‑2 Alters the Interactions with Monoclonal Antibodies from Class 2: A Free Energy Perturbation Study by Filip Fratev (1799740)

“…The <i>Mu</i> variant of SARS-CoV-2 has been recently classified as a variant of interest (VOI) by the World Health Organization (WHO) but limited data are available at the moment. …”

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“…We found that COL1A1 protein was decreased in the presence of 5-aza. …”

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“…The data obtained indicated that IgGs lacking α1–3 Galactose and Neu5Gc, two highly immunogenic epitopes in humans, have a protective effect upon EBOV infection.…”

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