Table_1_Upregulated MELK Leads to Doxorubicin Chemoresistance and M2 Macrophage Polarization via the miR-34a/JAK2/STAT3 Pathway in Uterine Leiomyosarcoma.XLSX by Zhiwei Zhang (12077)

“…We detected that MELK overexpression could induce M2 macrophage polarization via the miR-34a/JAK2/STAT3 pathway, contributing to doxorubicin chemoresistance in the tumor microenvironment. …”

Analysis of gene expression in the gut. by Sophie Candon (738601)

“…Results are expressed as fold of the mean expression observed in untreated mice. Only changes in expression levels outside the grey zone indicates changes in expression >2-fold increase or decrease in vancomycin-treated mice (black bars) as compared to controls (open bars). …”

Image3_Association Among the Gut Microbiome, the Serum Metabolomic Profile and RNA m6A Methylation in Sepsis-Associated Encephalopathy.jpg by Hui Wang (30400)

“…The diversity was decreased in the SAE gut microbiome, as characterized by a profound increase in commensals of the Acinetobacter, Methanobrevibacter, and Syner-01 genera, a decrease in [Eubacterium]_hallii_group, while depletion of opportunistic organisms of the Anaerofilum, Catenibacterium, and Senegalimassilia genera were observed in both groups. …”

Image1_Association Among the Gut Microbiome, the Serum Metabolomic Profile and RNA m6A Methylation in Sepsis-Associated Encephalopathy.jpg by Hui Wang (30400)

“…The diversity was decreased in the SAE gut microbiome, as characterized by a profound increase in commensals of the Acinetobacter, Methanobrevibacter, and Syner-01 genera, a decrease in [Eubacterium]_hallii_group, while depletion of opportunistic organisms of the Anaerofilum, Catenibacterium, and Senegalimassilia genera were observed in both groups. …”

Image2_Association Among the Gut Microbiome, the Serum Metabolomic Profile and RNA m6A Methylation in Sepsis-Associated Encephalopathy.jpg by Hui Wang (30400)

“…The diversity was decreased in the SAE gut microbiome, as characterized by a profound increase in commensals of the Acinetobacter, Methanobrevibacter, and Syner-01 genera, a decrease in [Eubacterium]_hallii_group, while depletion of opportunistic organisms of the Anaerofilum, Catenibacterium, and Senegalimassilia genera were observed in both groups. …”

Binding of 2′,3′-Cyclic Nucleotide Monophosphates to Bacterial Ribosomes Inhibits Translation by Shikha S. Chauhan (13839321)

“…Using <i>in vitro</i> translation assays, we have demonstrated that 2′,3′-cNMPs inhibit translation at concentrations found in amino acid-starved cells. …”

Binding of 2′,3′-Cyclic Nucleotide Monophosphates to Bacterial Ribosomes Inhibits Translation by Shikha S. Chauhan (13839321)

“…Using <i>in vitro</i> translation assays, we have demonstrated that 2′,3′-cNMPs inhibit translation at concentrations found in amino acid-starved cells. …”

DataSheet2_HIF-1/2α-Activated RNF146 Enhances the Proliferation and Glycolysis of Hepatocellular Carcinoma Cells via the PTEN/AKT/mTOR Pathway.ZIP by Guoliang Shen (5182778)

“…Either HIF-1α or HIF-2α knockdown significantly repressed hypoxia-induced RNF146 upregulation in Hep3B and Huh7 cells. …”

Table_2_Naringenin suppresses BEAS-2B-derived extracellular vesicular cargoes disorder caused by cigarette smoke extract thereby inhibiting M1 macrophage polarization.docx by Zhen Chen (129176)

“…In our previous study, we found that EVs derived from cigarette smoke extract (CSE) treated BEAS-2B promoted M1 macrophage polarization, which probably accelerated the development of inflammatory responses. …”

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and <i>De Novo</i> Lipogenesis of EGFRvIII Human Glioblastoma Cells by Jessica E. C. Jones (541168)

“…The impact of dual ACC1/ACC2 inhibition was investigated using a dual ACC1/ACC2 inhibitor as well as dual siRNA knock down on the cellular viability and metabolism of two glioblastoma multiform cancer cell lines, U87 and a more aggressive form, U87 EGFRvIII. …”

Image_2_Hypoxia-Inducible Factor 1α and 2α Have Beneficial Effects in Remote Ischemic Preconditioning Against Stroke by Modulating Inflammatory Responses in Aged Rats.TIF by Xiangnan Du (8552319)

“…The protein levels of p-Akt, Akt, p-ERK, and ERK were examined by WB. We investigated that RIPC reduced the infarct size, improved neurological functions, and decreased the expression of HIF-1α and HIF-2α in the ischemic brain. …”

DataSheet_2_Combination Treatment of CI-994 With Etoposide Potentiates Anticancer Effects Through a Topoisomerase II-Dependent Mechanism in Atypical Teratoid/Rhabdoid Tumor (AT/RT)... by Hee Yeon Kim (847060)

“…The enhanced effect of apoptosis by this combination treatment is related to a signaling pathway which decreases topoisomerase (Topo) II and increases histone H3 acetylation (Ac-H3).…”

Nitrogen-Use Efficiency, Nitrous Oxide Emissions, and Cereal Production in Brazil: Current Trends and Forecasts by Marcel Viana Pires (781264)

“…An increase of 0.02% per year in the projected NUE was predicted for the same time period. However, decreases in the projected CO₂ eq. emissions for future years were not predicted. …”

A <i>Becn1</i> mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease by Altea Rocchi (3278457)

“…We found that knock-in of a point mutation F121A in the essential autophagy gene Beclin 1/<i>Becn1</i> in mice significantly reduces the interaction of BECN1 with its inhibitor BCL2, and thus leads to constitutively active autophagy even under non-autophagy-inducing conditions in multiple tissues, including brain. …”

Single-Molecule Analysis of the Supramolecular Organization of the M₂ Muscarinic Receptor and the Gα_i1 Protein by Rabindra V. Shivnaraine (3097206)

“…That uncertainty relates to unresolved questions regarding the supramolecular nature of the signaling complex formed by receptor and G protein. We therefore have characterized the oligomeric status of eGFP-tagged M₂ muscarinic receptor (M₂R) and G_i1 by single-particle photobleaching of immobilized complexes. …”

Single-Molecule Analysis of the Supramolecular Organization of the M₂ Muscarinic Receptor and the Gα_i1 Protein by Rabindra V. Shivnaraine (3097206)

“…That uncertainty relates to unresolved questions regarding the supramolecular nature of the signaling complex formed by receptor and G protein. We therefore have characterized the oligomeric status of eGFP-tagged M₂ muscarinic receptor (M₂R) and G_i1 by single-particle photobleaching of immobilized complexes. …”

Single-Molecule Analysis of the Supramolecular Organization of the M₂ Muscarinic Receptor and the Gα_i1 Protein by Rabindra V. Shivnaraine (3097206)

“…That uncertainty relates to unresolved questions regarding the supramolecular nature of the signaling complex formed by receptor and G protein. We therefore have characterized the oligomeric status of eGFP-tagged M₂ muscarinic receptor (M₂R) and G_i1 by single-particle photobleaching of immobilized complexes. …”

Single-Molecule Analysis of the Supramolecular Organization of the M₂ Muscarinic Receptor and the Gα_i1 Protein by Rabindra V. Shivnaraine (3097206)

“…That uncertainty relates to unresolved questions regarding the supramolecular nature of the signaling complex formed by receptor and G protein. We therefore have characterized the oligomeric status of eGFP-tagged M₂ muscarinic receptor (M₂R) and G_i1 by single-particle photobleaching of immobilized complexes. …”

Submicroscopic malaria in pregnancy (sMiP) over the 4 years from 2012 to 2015. by Mary Ellen Gilder (8919374)

A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia by Ramon L. Serrano (6551279)

“…Cultured TG2-deficient VSMCs had decreased XBP1 associated with increased IRE1α, and increased migration in response to PDGF. …”