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DataSheet_2_Magnolol Prevents Acute Alcoholic Liver Damage by Activating PI3K/Nrf2/PPARγ and Inhibiting NLRP3 Signaling Pathway.zip
Published 2019“…The activities of PI3K, Nrf2, and NLRP3 signaling pathways activation were detected by western blotting analysis. …”
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40223
DataSheet_2_Magnolol Prevents Acute Alcoholic Liver Damage by Activating PI3K/Nrf2/PPARγ and Inhibiting NLRP3 Signaling Pathway.zip
Published 2019“…The activities of PI3K, Nrf2, and NLRP3 signaling pathways activation were detected by western blotting analysis. …”
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40224
DataSheet2_PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca2+/Calpain/VE-Cadherin Signaling.PDF
Published 2021“…Whether pulmonary endothelial cell ferroptosis occurs after IR and what are the underlying mechanisms remain elusive. Here, we demonstrate that 15-Gy IR induced ferroptosis characterized by lethal accumulation of reactive oxygen species (ROS), lipid peroxidation, mitochondria shrinkage, and decreased glutathione peroxidase 4 (GPX4) and SLC7A11 expression in pulmonary endothelial cells. …”
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40225
Table_2_The T Cell Receptor Immune Repertoire Protects the Liver From Reconsitution.xlsx
Published 2020“…Furthermore, we uncovered a novel fibrosis-associated CD8 T (Ccl5<sup>+</sup>, Ccl4<sup>+</sup>) and CD4 T (mt-Co1<sup>+</sup>) cell subpopulation, which infiltrates fibrotic liver and is characterized by abnormal activation or inactivation as well as a TCR decline. …”
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Table_2_Remarkable Protective Effects of Nrf2-Mediated Antioxidant Enzymes and Tissue Specificity in Different Skeletal Muscles of Daurian Ground Squirrels Over the Torpor-Arousal...
Published 2019“…Furthermore, relative to SA levels, malondialdehyde content decreased significantly during interbout arousal (IBA) and early torpor (ET) in all three skeletal muscles and decreased in the EDL and GAS during LT. …”
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40228
Differential suppression of a gelsolin sequence-tagged reporter gene by miR-133a isomiRs.
Published 2013“…<p>HEK293 cells were transfected with expression plasmids encoding mCherry with a 3′ partial gelsolin sequence and pSM30 containing inserts for miR-133a, miR-133a(v), a random non-targeting sequence (NTC) or siRNA against mCherry (siR-mCh). …”
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Image_1_The Two Translationally Controlled Tumor Protein Genes, CsTCTP1 and CsTCTP2, Are Negative Modulators in the Cucumis sativus Defense Response to Sphaerotheca fuliginea.pdf
Published 2018“…Here, we report two translationally controlled tumor protein genes, CsTCTP1 and CsTCTP2, that are both negative modulators in the Cucumis sativus defense response to Sphaerotheca fuliginea. …”
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40232
Table_2_Autophagy Induced by Palmitic Acid Regulates Neutrophil Adhesion Through the Granule-Dependent Degradation of αMβ2 Integrin in Dairy Cows With Fatty Liver.docx
Published 2021“…Autophagy is implicated in cell migration and tumor metastasis through facilitating the turnover of β1 integrins; however, whether autophagy is able to control neutrophil migration by promoting the degradation of β2 integrins is unexplored. Here, we show that high blood levels of palmitic acid (PA) strongly triggered neutrophil autophagy activation, leading to adhesion deficiency in dairy cows with fatty liver. …”
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40233
Image_2_Autophagy Induced by Palmitic Acid Regulates Neutrophil Adhesion Through the Granule-Dependent Degradation of αMβ2 Integrin in Dairy Cows With Fatty Liver.tif
Published 2021“…Autophagy is implicated in cell migration and tumor metastasis through facilitating the turnover of β1 integrins; however, whether autophagy is able to control neutrophil migration by promoting the degradation of β2 integrins is unexplored. Here, we show that high blood levels of palmitic acid (PA) strongly triggered neutrophil autophagy activation, leading to adhesion deficiency in dairy cows with fatty liver. …”
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NREM dependent reorganization differentially affects frequency of firing neurons during wake-like dynamics–model prediction and experiment.
Published 2021“…Neurons that increase their firing rate do so due to increased synaptic input, at the same time their mean strength of output connections decreases. <b>C)</b> Change in firing frequency (normalized to baseline) as a function of normalized baseline firing frequency in the absence of inhibition. …”
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Intervention Scenarios with Limited AV Supplies: Global Attack Rates
Published 2013“…Given the rate of distribution <i>p<sub>AV</sub></i>, the value of the reproductive rate <i>R<sub>0</sub></i> up to which cooperative strategies effectively contain the pandemic are reported, <i>R<sub>0</sub> =</i> 1.9 and <i>p<sub>AV</sub></i> = 0.7/d (A), <i>R<sub>0</sub></i> = 1.7 and <i>p<sub>AV</sub></i> = 0.5/d (C), <i>R<sub>0</sub></i> = 1.5 and <i>p<sub>AV</sub></i> = 0.3/d (E).…”
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<b>Protective role of protease-activated receptor-2 in anaphylaxis model mice</b>
Published 2024“…Among the various mediators of mast cells, little is known about the role of tryptase. Therefore, we aimed to elucidate the role of protease-activating receptor-2 (PAR-2), a receptor activated by tryptase, in murine anaphylactic models using PAR-2-deficient mice and newly generated tryptase-deficient mice. …”
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40240
Image_2_Alterations in the Gut Microbiota and Hepatitis-B-Virus Infection in Southern Chinese Patients With Coexisting Non-Alcoholic Fatty Liver Disease and Type-2 Diabetes Mellitu...
Published 2021“…<p>Background: Hepatitis B virus (HBV) infection has been reported to affect the bacterial characteristics in the host. We aimed to elucidate the compositional and functional characteristics of the microbiota in southern Chinese patients with coexistent HBV infection, non-alcoholic fatty liver disease (NAFLD), and type-2 diabetes mellitus (T2DM).…”