Laminar flow increases the expression of anti-oxidant genes and decreases the inflammatory basal state of GEnC. by Daan C. ‘t Hart (10751645)

NOX1 activation by ET-1 decreased CD38 in the plasma membrane measured by biotinylated trapping. by Ming Xu (151206)

Decreased factor XIIIa protein levels in the tibial growth plate under PI3K inhibition. by Veronica Ulici (76661)

“…<p>(A) E15.5 mouse tibiae cultured for 6 days in the presence of DMSO or 10 µM LY294002 were processed for immunohistochemistry. …”

Rate ratios among children aged 5–17 years by outcome comparing COVID-19 pediatric vaccination coverage quartiles of states to states in the highest vaccination coverage quartile d... by Katherine G. Topf (14241763)

Changes in the concentration of FLU ophthalmic suspensions contained in one drop following agitation by different methods. by Tokio Obata (10783047)

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

TGFβ receptor reconstitution leads to decreased metastatic colonization: Impact on TGFβ/PKA signaling. by Sanjib Chowdhury (222280)

S1 Data - by Michael C. Beall (18764654)

“…Germination occurred across a temperature range of 8–37°C and a pH range of 5–10 (≥83%), suggesting that neither pH nor temperature will limit germination in many environments. …”

Treatment with rVP1 decreases NF-κB activation that modulates CCL2 production. by Tai-An Chen (211390)

<i>GSK-3β</i> −/− embryos exhibit decreased osteogenic gene expression in the palatine bones. by Emily R. Nelson (247130)

“…Scale bars in higher magnification images (second and fourth) represent 100 µm. (D) qRT-PCR of e15.5 <i>GSK-3β</i> +/+ and −/− embryos. <i>GSK-3β</i> −/− embryos display significantly decreased levels of the osteogenic genes <i>Alp</i>, <i>Runx2</i>, <i>Ocn</i>, and <i>Col1a1</i> by qRT-PCR, in comparison to wild-type littermates. …”

Down-regulation of Bim in EBV-positive cells is not due to proteosomal degradation or decreased mRNA stability. by Kostas Paschos (262658)

Rapid reduction of HbA1c and early worsening of diabetic retinopathy: A real-world population-based study in subjects with type 2 diabetes by Rafael Simó (186568)

“…The main variable analyzed was the magnitude of the reduction of HbA1c in previous 12 months. The reduction of HbA1c was categorized in rapid (>1.5% reduction in < 12 months) and very rapid (>2% in <6 months). …”

Fixation becomes unlikely with decreasing fitness of mutant homozygotes, variance in allele frequency increases with migration rate. by Philipp M. Altrock (340203)

Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”

Decreased expression of transferrin receptor (TfR) but not transferrin (Tf) in R6/2 HD mice. by Jianfang Chen (469733)

“…<b>A</b>. Representative images indicate decreased TfR immunoreactivity in HD TG cortex and striatum as compared to wild-type mice at 12-weeks of age. …”

Total plasma cortisol concentration over time following intramuscular administration of either 0.1 mL saline, 0.4 mg/kg meloxicam, 2.2 mg/kg flunixin or 3.0 mg/kg ketoprofen in 6-d... by Emma Nixon (11772946)