Honokiol inhibits the EGFR signaling pathway and downregulates STAT3 target genes in multidrug-sensitive and -resistant cells. by Xu Wang (28596)

“…The effect of honokiol at early time points: (<b>a</b>) phosphorylation of EGFR and STAT3; (<b>b</b>) Honokiol decreases phosphorylation of AKT and ERK. …”

Subcellular localization of Id2. by David C. Butler (261919)

“…<p>(A) Nuclear Id2 expression is decreased in myoblasts overexpressing S5A:GFP. …”

Image 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.tif by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Data_Sheet_1_Probiotics Exhibit Strain-Specific Protective Effects in T84 Cells Challenged With Clostridioides difficile-Infected Fecal Water.pdf by Mohd Baasir Gaisawat (12000860)

“…We assessed five single-strain and three multi-strain probiotics for their ability to modulate CDI fecal water (FW)-induced effects on T84 cells. …”

Reappraisal of the Trophic Ecology of One of the World’s Most Threatened Spheniscids, the African Penguin by Maëlle Connan (680842)

“…The world population of the endangered African penguin <i>Spheniscus demersus</i> has decreased from more than 1.5 million individuals in the early 1900s to c.a. 23 000 pairs in 2013. …”

The impact of the COVID-19 lockdown on urban street litter in South Africa by Peter G Ryan (7887212)

“…The lockdowns instigated to slow the spread of the COVID-19 pandemic offered a unique opportunity to assess how restrictions on human activity affect street litter. We recorded daily litter arrival rates for 50 days in two South African cities from the time of strictest lockdown through two successive easings in regulations. …”

Data_Sheet_1_Long-term trends in the burden of inflammatory bowel disease in China over three decades: A joinpoint regression and age-period-cohort analysis based on GBD 2019.PDF by Yang Zhang (30734)

“…</p>Methods<p>We characterized the burden of IBD in China using the GBD 2019 methods and results, based on prevalence, incidence, mortality, years lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs) estimated using the DisMod-MR 2-1. …”

Intelligibility of dysphonic speech in classrooms (Botallico et al., 2023) by Pasquale Bottalico (16318258)

Twin pulse stimulation reveals two distinct populations. by Matthias Ringkamp (253465)

Presentation_1_Characterization, Hypoglycemic Activity, and Antioxidant Activity of Methanol Extracts From Amomum tsao-ko: in vitro and in vivo Studies.pdf by Libin Xie (12075542)

“…In an animal experiment conducted on oxidative damage mice model which was induced by D-glucose and a high-fat diet, we observed significantly increased dismutase (SOD) (p < 0.01), glutathione (GSH) (p < 0.01), and glutathione peroxidase (GSH-Px) (p < 0.01) and significantly reduced malondialdehyde (MDA) and 8-ISO-prostaglandin-PGF2α (8-ISO-PGF2α), after treatment with PMEAT for 90 days. …”

Molecular-genetic causes for the high frequency of phenylketonuria in the population from the North Caucasus by Polina Gundorova (5580134)

“…The p.Arg261* variant occurred in the Karachays population 10.2 ± 2.7 generations ago (275 ± 73 years) and its spread occurred in parallel with the growth of the population.…”

Biomass Production from Electricity Using Ammonia as an Electron Carrier in a Reverse Microbial Fuel Cell by Wendell O. Khunjar (134130)

“…The net result is a separate-stage reverse microbial fuel cell (rMFC) that fixes CO₂ into biomass using electrical energy. We selected ammonia as a low cost, abundant, safe, and soluble redox mediator that facilitated energy transfer to biomass. …”

Data_Sheet_1_IL-6/STAT3 Signaling Promotes Cardiac Dysfunction by Upregulating FUNDC1-Dependent Mitochondria-Associated Endoplasmic Reticulum Membranes Formation in Sepsis Mice.doc... by Tao Jiang (28401)

“…Dual-luciferase reporter assay was used to confirm that STAT3 was a potential transcription factor for FUNDC1. Moreover, we showed that LPS increased MAMs formation and intracellular Ca²⁺ levels, enhanced the expression of Cav1.2 and RyR2, decreased mitochondrial membrane potential and intracellular ATP levels, and promoted mitochondrial fragmentation, the expression of mitophagy proteins and ROS production in H9c2 cells, which were reversed by knockdown of FUNDC1 and IL-6/STAT3 inhibitor including Bazedoxifene and Stattic.…”

Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy by Xiao Guo (542560)

“…Moreover, hyperoside administration repressed apoptosis as evidenced by changing apoptosis-related protein levels, and promoted autophagy in TAC rats and angiotensin II (AngII)-induced H9C2 cells. Inhibition of autophagy by 3-methyladenine (3-MA) attenuated the beneficial effect of hyperoside against apoptosis in H9C2 cells. …”

Primer sequences for RT-qPCR. by Jinyan Feng (13016481)

“…</p><p>Results</p><p>A total of six cuproptosis-mitochondrion genes (FDX1, COX11, MFN2, TOMM20, NDUFB9 and ATP6V1E1) were identified. …”

Estrogen and Progesterone Regulate p27kip1 Levels via the Ubiquitin-Proteasome System: Pathogenic and Therapeutic Implications for Endometrial Cancer by Kuang-Tzu Huang (132734)

“…In addition, E2 decreases the E3 ligase [APC]Cdh1 leaving Skp2 and Cks1 intact to cause p27 degradation. …”

Supplementary Material for: Adoptively Transferred in vitro-Generated Myeloid-Derived Suppressor Cells Improve T-Cell Function and Antigen-Specific Immunity after Traumatic Lung In... by Kustermann M. (12857240)

“…A single MDSC treatment-induced splenic T-cell expansion decreased apoptosis sensitivity and improved proliferation in the absence of T-cell exhaustion until 2 weeks after trauma. …”

Chronic gastric electrical stimulation leads to weight loss via modulating multiple tissue neuropeptide Y, orexin, α-melanocyte-stimulating hormone and oxytocin in obese rats by Yun Yan (387870)

“…</i></b> Most of the experiments included three groups of diet-induced obesity rats: (1) sham-GES (SGES); (2) GL-6mA (GES with 6 mA, 4 ms, 40 Hz, 2 s on, 3 s off at lesser curvature); and (3) SGES-PF (SGES rats receiving pair feeding to match the consumption of GL-6mA rats). …”

Main results of computed SGN conduction times. by Frank Rattay (127304)

“…The process diameter enlargement at the soma position (d2 = 2*d1) is not as effective as in the myelinated cases. Angles between v2 and v1 slopes (green circle arrows) point out small velocity changes (small velocity ratio v2/v1) in unmyelinated type II neurons (upper green circle) compared to type I ganglion cells (lower green circle arrows).…”