Oxidative stress and fish immune system: phagocytosis and leukocyte respiratory burst activity by JAQUELINE D. BILLER (5888066)

ABSORPTIVE CAPACITY, INNOVATION, AND EXTERNAL SOURCES OF KNOWLEDGE: THE BRAZILIAN POWER SECTOR by ÂNGELA F. VERSIANI (12656755)

Physico-chemical characteristics of passion fruit flour under removal of flavedo and of maceration by Elaine C. O. da Silva (7503632)

Identification of the transgene insertion site for an adipocyte-specific adiponectin-cre model and characterization of the functional consequences by Jared S. Farrar (10124891)

Image_4_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Table_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.pdf by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_3_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Permutation test for contaminated data and skewness analysis by Jaroslav Flegr (771164)

“…</p> <p><b>Methods:</b> We used a Monte Carlo simulation in the program R to show that the permutation test implemented in the programs Treept and PTPT is a conservative test. …”

Wood basic density effect of Eucalyptus grandis in the paper making by Victor Gonçalves Cremonez (6699275)

“…In this article, it was evaluated wood chips from a five-years-old Eucalyptus grandis in three different silvicultural treatments for pulp and paper production. …”

The Brazilian market for monoclonal antibodies used in cancer treatment by Thaís Jeronimo Vidal (6049085)

“…It is expected that the development of new products, although to act on the same biological target, represent the possibility of a competitive increase and, as a result, a decrease in prices practiced by companies. …”

Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine by L.F. Martins (10387265)

Cloning of the growth hormone receptor and its muscle-specific mRNA expression in black Muscovy duck (<i>Cairina moschata</i>) by W. Ji (2238484)

ferrinetal_Interactiveeffectsofwarmingabandnanoonthegutmicrobiomeofsoilcollembola by Miquel Ferrín Guardiola (14050848)

“…Little is known, however, about their gut microbiome and how it might respond to warming and these pollutants. We exposed populations of <i>F. candida</i> in microcosms to either nanoplastics or an antibiotic under two temperatures. …”

Ecological generalism and physiology mediate species biogeographic ranges under ocean warming by Chloe Hayes (10074739)

“…One temperate species showed decreased abundance, habitat niche width, and physiological performance at their warm-trailing edge compared to their core temperate range, while the other two temperate species showed contrasting responses. …”

Metabolic enzymes modified by phosphorylation and metabolites quantification in trypomastigotes incubated with ECM. by Eliciane C. Mattos (129459)

“…<p>(A) Schematic representation of enzymes from the glycolytic and glycolytic branch modified by phosphorylation (green) or dephosphorylation (red) and metabolites that increase (green) or decrease (red) after trypomastigotes incubation with ECM for 120 min. …”

Redox Conductivity of Current-Producing Mixed Species Biofilms by Cheng Li (6339)

“…Electrochemical gating analysis of the biofilms over a range of potentials (-600–200 mV, vs. Ag/AgCl) resulted in a peak-manner response with maximum conductance of 3437 ± 271 μS at a gate potential of -360 mV. …”

Myotonia-causing mutations and the putative binding pocket of the 9-AC inhibitor. by Kaituo Wang (6193994)

“…We note that mutations of 5 residues that cause recessive myotonia and inward rectification are facing the extracellular vestibule; 3 located in a row on the same face of on helix B (M128, S132, D136) and 2 being the pore-constricting residues (K231, R421). …”

VPA reduces burn-induced increase in MLCK. by Hong-Min Luo (473535)

“…VPA treatment significantly decreased intestinal MLCK at 6 hours post-burn. Protein bands quantified by densitometry were expressed as mean values ± SD (n=5). * <i>P</i> < 0.05, compared with Sham+NS group; # <i>P</i> < 0.05, compared with Scald+NS group.…”

Molecular regulation of miR-378 on the development of mouse follicle and the maturation of oocyte in vivo by Xiao-Feng Sun (149119)

“…The results showed that CMV-miR-378 lentivirus transduction in the mouse ovaries resulted in reduced ovary size, extended oestrous cycle (6-7 d in miR-378 overexpression group and 4–5 dyas in GFP control group) due to continuous oestrum, decreased percentage of oocytes in vitro maturation rate (IVM 60.8% vs. 89.4% in GFP control), increased apoptosis rate (Bax/Bcl2 in mRNA and protein level), decreased expression of genes associated with gap junction, such as connexin 43 (Cx-43) and connexin (Cx-37) and decreased expression of genes associated with follicular development, such as BMP15 and GDF9. …”