Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution by Oliver Grottke (584154)

“…Idarucizumab was then administered intravenously (30 mg/kg) and serial blood samples were taken for up to 24 hours to measure diluted thrombin time (corresponding with dabigatran activity), total dabigatran (bound to antidote and free drug) and a panel of coagulation parameters.</p><p>Results</p><p>Mean plasma dabigatran levels were 617 ± 16 ng/mL after infusion and 600 ± 114 ng/mL after ~50% hemodilution with no significant differences between groups. …”

Supplementary Material for: Preoperative prediction of microvascular invasion with gadoxetic acid-enhanced magnetic resonance imaging in patients with single hepatocellular carcino... by Kim N.R. (16500675)

“…Methods: Patients with surgically resected single HCC (≤5 cm) who underwent preoperative gadoxetic acid-enhanced magnetic resonance imaging (MRI) were included in a single-center retrospective study. …”

CaMKII inhibition attenuates p38MAP activation and p47^phox membrane translocation in rat hippocampal slice cultures exposed to oxygen glucose deprivation. by Qing Lu (28914)

“…<p>Rat hippocampal slice cultures were exposed to OGD in the presence of the CaMKII inhibitor, KN93 or its inactive analog, KN92 (10 µM, 2 h prior to OGD), harvested 2 h after OGD and subjected to Western blotting using antibodies specific to phospho- and total-p38MAPK to estimate the effect on p38MAPK activation (A). OGD increases phospho-p38MAPK to total p38MAPK ratio and this is decreased by KN93 (A). …”

Supplementary Material for: Preoperative prediction of microvascular invasion with gadoxetic acid-enhanced magnetic resonance imaging in patients with single hepatocellular carcino... by Kim N.R. (16500675)

“…Methods: Patients with surgically resected single HCC (≤5 cm) who underwent preoperative gadoxetic acid-enhanced magnetic resonance imaging (MRI) were included in a single-center retrospective study. …”

Men and women differ with regard to the prevalence, phenotype, and prognosis of wild-type transthyretin amyloid cardiomyopathy by Amira Zaroui (11436866)

“…</p> <p>In a retrospective cohort study at a reference centre in France from 1 January 2008 to 31 December 2022, multiple regression analyses, supervised clustering, Cox models, and a Kaplan-Meier analysis were used to compare women and men in each age quartile (Q1: ≤77 years; Q2: 78–82; Q3: 83–86; Q4 > 86).</p> <p>We included 1062 patients with ATTRwt-CM (180 women, 16%). …”

Time-course of average central corneal thickness after human corneal endothelial cell sheet transplantation by Kouichiro Hitani (43561)

Simulation of constant current injection into the B1 motoneuron in normal saline and with octopamine by Ágnes Vehovszky (14366)

“…Comparison of the action potential generated by simulation with one recorded in a constant current experiment in normal saline (initial resting potential -48 mV, slightly depolarised compared to the mean B1 resting potential, -55 mV). …”

Non-competitive inhibition of odorant activation of an insect OR by an Orco antagonist. by Sisi Chen (166395)

“…Increasing the concentration of Orco agonist (OLC12) decreases the effectiveness of OX1a. Oocytes expressing Cqui\Orco+Cqui\Or21 were activated with 3 µM or 30 µM OLC12, in the absence or presence of 30 µM or 100 µM OX1a. …”

Optimal virtual network function placement in multi-cloud service function chaining architecture by Bhamare, Deval

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Data_Sheet_1_Cerebrovascular Pathology in Hypertriglyceridemic APOB-100 Transgenic Mice.docx by Zsófia Hoyk (5893889)

“…In brain microvessels isolated from APOB-100 transgenic animals increased Lox-1, Aqp4, and decreased Meox-2, Mfsd2a, Abcb1a, Lrp2, Glut-1, Nos2, Nos3, Vim, and in transgenic brains reduced Cdh2 and Gfap-σ gene expressions were measured using quantitative real-time PCR. …”

Data_Sheet_3_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.docx by Su Liu (1965895)

“…The results showed that there was a significant difference in the overall composition of GMB between the two groups (p = 0.005). …”

Data_Sheet_1_Analysis of gut microbiome composition, function, and phenotype in patients with osteoarthritis.xlsx by Su Liu (1965895)

“…The results showed that there was a significant difference in the overall composition of GMB between the two groups (p = 0.005). …”

Silencing MFN1 or MFN2 reveals their distinct roles in DENV infection. by Chia-Yi Yu (141345)

“…Data in panels A and C-F are mean ± SD (<i>n = 3</i> per group) and were compared by two-tailed Student’s <i>t</i> test. …”

Mst1^−/− mice exhibit blunted MOG-specific proliferative and effector cytokine recall responses in vivo. by Konstantin V. Salojin (567844)

“…(<b>D</b>) Mice treated with an Mst1 inhibitor exhibit decreased severity of EAE. EAE was induced in C57Bl/6-Albino/129SvEv mice (n = 10 per treatment group) by immunization with MOGp35–55 in CFA and treated twice daily with the indicated doses of the Mst1 inhibitor LP-945706 administered by oral gavage in citrate buffed (pH 4.5, 0.1 M) 1% Tween 80 vehicle, starting one day after the onset of disease in 50% of the animals. …”

Effective recovery time and synaptic integration time during scratching. by Rune W. Berg (54068)

“…<p>Peri-spike V_m distribution in quiescence (A) (n = 50) and during scratching (B) (n = 29). …”

Community Shifts in the Surface Microbiomes of the Coral <i>Porites astreoides</i> with Unusual Lesions by Julie L. Meyer (579316)

“…The presence of lesions in <i>P. astreoides</i> coincided with a decrease in the relative abundance of <i>Endozoicomonas</i>, rather than the appearance of specific pathogenic taxa.…”

Student anxiety in introductory biology classrooms: Perceptions about active learning and persistence in the major by Benjamin J. England (4330633)

“…The survey (n = 327) data revealed that 16% of students had moderately high classroom anxiety, which differed among the three classes. All five active learning classroom practices that were investigated caused student anxiety, with students voluntarily answering a question or being called on to answer a question causing higher anxiety than working in groups, completing worksheets, or answering clicker questions. …”

Safety and Efficacy of Ustekinumab and Vedolizumab Among Older Adults with Inflammatory Bowel Disease by Moniyka Sachar (9399032)

Data Sheet 1_Changes in subarctic Pacific phytoplankton communities over the last two decades.docx by Marta Konik (11610847)

Effect of Polymer Cross-Links on Oxygen Diffusion in Glassy PMMA Films by Markus Klinger (2384596)