Image_1_Extracellular matrix and dermal nerve growth factor dysregulation in prurigo nodularis compared to atopic dermatitis.JPEG by Junwen Deng (1920052)

“…Transcriptomic analysis of skin biopsies revealed that compared to lesional AD skin, lesional PN skin had significantly increased expression of NGF, matrix metalloproteinases, OSM, MCEMP1, IL1α, IL1β, CXCL2, CXCL5, CXCL8, and insulin-like growth factors in PN compared to AD, and decreased expression of CCL13, CCL26, EPHB1, and collagens (COL4/6). …”

Image_1_Adeno-associated virus vector intraperitoneal injection induces colonic mucosa and submucosa transduction and alters the diversity and composition of the faecal microbiota... by Li-Tian Ma (13263204)

“…</p>Results<p>Our results showed (1) efficient transduction of the mucosa and submucosa of the ascending, transverse, and descending colon following AAV9 IP injection; (2) a decreased alpha diversity and an altered overall microbial composition following AAV9 IP injection; (3) significant enrichments in a total of 5 phyla, 10 classes, 13 orders, 15 families, 29 genera, and 230 OTUs following AAV9 IP injection; and (4) AAV9 can significantly upregulate the relative abundance of anaerobic microbiota which is one of the seven high-level phenotypes that BugBase could predict.…”

Data_Sheet_1_Spatial Distribution of Arctic Bacterioplankton Abundance Is Linked to Distinct Water Masses and Summertime Phytoplankton Bloom Dynamics (Fram Strait, 79°N).doc by Magda G. Cardozo-Mino (10146053)

“…Using CARD-FISH and semi-automated counting, we quantified 14 ecologically relevant taxonomic groups of bacterioplankton (Bacteria and Archaea) from surface (0–30 m) down to deep waters (2,500 m) in summer ice-covered and ice-free regions of the Fram Strait, the main gateway for Atlantic inflow into the Arctic Ocean. …”

DataSheet1_Alteration of the Sitting and Standing Movement in Adult Spinal Deformity.DOCX by Eddy Saad (11939807)

“…During sit-to-stand and stand-to-sit movements, ASD-sag had decreased pelvic anteversion (12.2 vs 15.2°), hip flexion (53.0 vs 62.2°), sagittal mobility in knees (87.1 vs 93.9°), and lumbar mobility (L1L3-L3L5: −9.1 vs −6.8°, all p < 0.05) compared with controls. …”

Table_3_A new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics.xlsx by Yi Guo (35817)

“…An integrated analysis of the metabolome and proteome identified differential energy metabolism and oxidative stress-related proteins, which could explain the decreased motility and the increased DFI of aging sperm</p>Discussion and conclusion<p>We provide compelling evidence that the changes in semen metabolome and sperm proteome are related to the decline of semen quality in aged males. …”

Table_1_A new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics.docx by Yi Guo (35817)

“…An integrated analysis of the metabolome and proteome identified differential energy metabolism and oxidative stress-related proteins, which could explain the decreased motility and the increased DFI of aging sperm</p>Discussion and conclusion<p>We provide compelling evidence that the changes in semen metabolome and sperm proteome are related to the decline of semen quality in aged males. …”

Image_1_A new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics.jpg by Yi Guo (35817)

“…An integrated analysis of the metabolome and proteome identified differential energy metabolism and oxidative stress-related proteins, which could explain the decreased motility and the increased DFI of aging sperm</p>Discussion and conclusion<p>We provide compelling evidence that the changes in semen metabolome and sperm proteome are related to the decline of semen quality in aged males. …”

“Deep” Sequencing Accuracy and Reproducibility Using Roche/454 Technology for Inferring Co-Receptor Usage in HIV-1 by David J. H. F. Knapp (444976)

“…For repeated measurements of a non-homogeneous clinical sample, increasing input copy number both decreased variance in the measured proportion of non-R5 using virus (p<<0.001 and 0.02 for single replicates and triplicates respectively) and increased measured viral diversity (p<0.001; multiple measures). …”

RNAi of candidate anti-pairers enhances heterochromatic pairing frequencies. by Eric F. Joyce (165338)

“…<p>a, Representative FISH images are shown for RNAi depletion of anti-pairers (<i>cdk8</i>, <i>cap-H2</i>, and <i>orc1</i>), where the number of FISH signals per nucleus is decreased as compared to that of control. …”

“Deep” Sequencing Accuracy and Reproducibility Using Roche/454 Technology for Inferring Co-Receptor Usage in HIV-1 by David J. H. F. Knapp (444976)

“…For repeated measurements of a non-homogeneous clinical sample, increasing input copy number both decreased variance in the measured proportion of non-R5 using virus (p<<0.001 and 0.02 for single replicates and triplicates respectively) and increased measured viral diversity (p<0.001; multiple measures). …”

Fecal Carriage and Molecular Characterization of Carbapenemase-Producing Enterobacterales in the Pediatric Population in Qatar by Pérez-López, Andrés

“…All 9 blaOXA-48-type-gene-containing E. coli sequence type 38 (ST38) strains were isolated from patients without international travel history. The mean quarterly incidence of fecal carriage decreased more than 6-fold after the implementation of coronavirus disease 2019 (COVID-19)-related international travel restrictions in Qatar in mid-March 2020. …”
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Table_1_Association between body mass index and cognitive impairment in Chinese older adults.DOCX by Wenshuo Dong (17198704)

“…In particular, the risk of cognitive impairment was higher at a lower baseline BMI. In contrast, BMI in the range of 23.2–27.8 kg/m² was associated with a decreased risk of cognitive impairment.…”

Supplementary Material for: Inconsistent skin prick tests for allergy to birch homologous trees may result from cross-reacting allergens or technical errors by Beutner C. (8086184)

“…Introduction: Skin prick tests (SPTs) are the gold standard for diagnosis of allergic rhinitis (AR). A decrease in the number of allergens included in standard SPT panels has recently been debated—particularly regarding the cross-reacting homologous pollen from birch, alder and hazel trees—but has not yet been implemented in clinical guidelines. …”

Table_4_m6A Modification Mediates Mucosal Immune Microenvironment and Therapeutic Response in Inflammatory Bowel Disease.DOC by Yongyu Chen (8477316)

“…We found that IGF2BP1 and IGF2BP2 expression was decreased in Crohn’s disease (CD) tissues and that IGF2BP2 was decreased in ulcerative colitis (UC) tissues compared with normal tissues (P < 0.05). m⁶Acluster2, containing higher expressions of IL15, IL16, and IL18, was enriched in M0 macrophage, M1 macrophage, native B cells, memory B cells, and m⁶Acluster1 with high expression of IL8 and was enriched in resting dendritic and plasma cells (P < 0.05). …”

Image_1_m6A Modification Mediates Mucosal Immune Microenvironment and Therapeutic Response in Inflammatory Bowel Disease.TIF by Yongyu Chen (8477316)

“…We found that IGF2BP1 and IGF2BP2 expression was decreased in Crohn’s disease (CD) tissues and that IGF2BP2 was decreased in ulcerative colitis (UC) tissues compared with normal tissues (P < 0.05). m⁶Acluster2, containing higher expressions of IL15, IL16, and IL18, was enriched in M0 macrophage, M1 macrophage, native B cells, memory B cells, and m⁶Acluster1 with high expression of IL8 and was enriched in resting dendritic and plasma cells (P < 0.05). …”

Table_6_m6A Modification Mediates Mucosal Immune Microenvironment and Therapeutic Response in Inflammatory Bowel Disease.DOC by Yongyu Chen (8477316)

“…We found that IGF2BP1 and IGF2BP2 expression was decreased in Crohn’s disease (CD) tissues and that IGF2BP2 was decreased in ulcerative colitis (UC) tissues compared with normal tissues (P < 0.05). m⁶Acluster2, containing higher expressions of IL15, IL16, and IL18, was enriched in M0 macrophage, M1 macrophage, native B cells, memory B cells, and m⁶Acluster1 with high expression of IL8 and was enriched in resting dendritic and plasma cells (P < 0.05). …”

Table_3_m6A Modification Mediates Mucosal Immune Microenvironment and Therapeutic Response in Inflammatory Bowel Disease.DOC by Yongyu Chen (8477316)

“…We found that IGF2BP1 and IGF2BP2 expression was decreased in Crohn’s disease (CD) tissues and that IGF2BP2 was decreased in ulcerative colitis (UC) tissues compared with normal tissues (P < 0.05). m⁶Acluster2, containing higher expressions of IL15, IL16, and IL18, was enriched in M0 macrophage, M1 macrophage, native B cells, memory B cells, and m⁶Acluster1 with high expression of IL8 and was enriched in resting dendritic and plasma cells (P < 0.05). …”

Table_7_m6A Modification Mediates Mucosal Immune Microenvironment and Therapeutic Response in Inflammatory Bowel Disease.DOC by Yongyu Chen (8477316)

“…We found that IGF2BP1 and IGF2BP2 expression was decreased in Crohn’s disease (CD) tissues and that IGF2BP2 was decreased in ulcerative colitis (UC) tissues compared with normal tissues (P < 0.05). m⁶Acluster2, containing higher expressions of IL15, IL16, and IL18, was enriched in M0 macrophage, M1 macrophage, native B cells, memory B cells, and m⁶Acluster1 with high expression of IL8 and was enriched in resting dendritic and plasma cells (P < 0.05). …”

Table_1_m6A Modification Mediates Mucosal Immune Microenvironment and Therapeutic Response in Inflammatory Bowel Disease.DOC by Yongyu Chen (8477316)

“…We found that IGF2BP1 and IGF2BP2 expression was decreased in Crohn’s disease (CD) tissues and that IGF2BP2 was decreased in ulcerative colitis (UC) tissues compared with normal tissues (P < 0.05). m⁶Acluster2, containing higher expressions of IL15, IL16, and IL18, was enriched in M0 macrophage, M1 macrophage, native B cells, memory B cells, and m⁶Acluster1 with high expression of IL8 and was enriched in resting dendritic and plasma cells (P < 0.05). …”

Data_Sheet_1_Distinct Treatment Outcomes of Antiparasitic Therapy in Trypanosoma cruzi-Infected Children Is Associated With Early Changes in Cytokines, Chemokines, and T-Cell Pheno... by María C. Albareda (166561)

“…</p><p>Results: Treatment with benznidazole or nifurtimox induced a decline in T. cruzi-specific IFN-γ- and IL-2-producing cells and proinflammatory cytokines and chemokines. …”