Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Infection decreases short chain phospholipids in the intestines of <i>V</i>. <i>cholerae</i>-infected flies. by Audrey S. Vanhove (4090594)

Nucleophilicity of Oximes Based upon Addition to a Nitrilium <i>closo</i>-Decaborate Cluster by Dmitrii S. Bolotin (1953220)

Nucleophilicity of Oximes Based upon Addition to a Nitrilium <i>closo</i>-Decaborate Cluster by Dmitrii S. Bolotin (1953220)

Propensity-score matched open aortic group. by Tomi Obafemi (12328433)

“…However, the incidence of post-op ventilator associated pneumonia (VAP) decreased from 5.0% to 2.1% (p = 0.003) and post-op urinary tract infections (UTIs) from 8.3% to 3.6% (p<0.001). …”

Pre-match open aortic group. by Tomi Obafemi (12328433)

“…However, the incidence of post-op ventilator associated pneumonia (VAP) decreased from 5.0% to 2.1% (p = 0.003) and post-op urinary tract infections (UTIs) from 8.3% to 3.6% (p<0.001). …”

Pre-match CABG/Valve group. by Tomi Obafemi (12328433)

“…However, the incidence of post-op ventilator associated pneumonia (VAP) decreased from 5.0% to 2.1% (p = 0.003) and post-op urinary tract infections (UTIs) from 8.3% to 3.6% (p<0.001). …”

Propensity-score matched CABG/Valve group. by Tomi Obafemi (12328433)

“…However, the incidence of post-op ventilator associated pneumonia (VAP) decreased from 5.0% to 2.1% (p = 0.003) and post-op urinary tract infections (UTIs) from 8.3% to 3.6% (p<0.001). …”

Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

MeV <i>M</i> mRNA quantification in cells treated with an inhibitor of RNA polymerase III. by Pierre Khalfi (7868252)

Subjects:

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

Soil Carbon Stocks Decrease following Conversion of Secondary Forests to Rubber (<i>Hevea brasiliensis</i>) Plantations by Marleen de Blécourt (435325)