Image_6_Elevated temperatures and longer durations improve the efficacy of oxaliplatin- and mitomycin C-based hyperthermic intraperitoneal chemotherapy in a confirmed rat model for... by Roxan F. C. P. A. Helderman (14807512)

“…This combined treatment modality using HIPEC with mitomycin C (MMC) for 90 minutes proved to be superior to systemic chemotherapy alone, but no benefit of adding HIPEC to CRS alone was shown using oxaliplatin-based HIPEC during 30 minutes. We investigated the impact of treatment temperature and duration as relevant HIPEC parameters for these two chemotherapeutic agents in representative preclinical models. …”

Image_9_Elevated temperatures and longer durations improve the efficacy of oxaliplatin- and mitomycin C-based hyperthermic intraperitoneal chemotherapy in a confirmed rat model for... by Roxan F. C. P. A. Helderman (14807512)

“…This combined treatment modality using HIPEC with mitomycin C (MMC) for 90 minutes proved to be superior to systemic chemotherapy alone, but no benefit of adding HIPEC to CRS alone was shown using oxaliplatin-based HIPEC during 30 minutes. We investigated the impact of treatment temperature and duration as relevant HIPEC parameters for these two chemotherapeutic agents in representative preclinical models. …”

Data_Sheet_1_Gut-microbiome-based predictive model for ST-elevation myocardial infarction in young male patients.docx by Mingchuan Liu (7040438)

“…</p>Conclusion<p>In this study, we combined the gut microbiome and common clinical parameters to construct a prediction model. …”

Image_1_Elevated temperatures and longer durations improve the efficacy of oxaliplatin- and mitomycin C-based hyperthermic intraperitoneal chemotherapy in a confirmed rat model for... by Roxan F. C. P. A. Helderman (14807512)

“…This combined treatment modality using HIPEC with mitomycin C (MMC) for 90 minutes proved to be superior to systemic chemotherapy alone, but no benefit of adding HIPEC to CRS alone was shown using oxaliplatin-based HIPEC during 30 minutes. We investigated the impact of treatment temperature and duration as relevant HIPEC parameters for these two chemotherapeutic agents in representative preclinical models. …”

Image_4_Elevated temperatures and longer durations improve the efficacy of oxaliplatin- and mitomycin C-based hyperthermic intraperitoneal chemotherapy in a confirmed rat model for... by Roxan F. C. P. A. Helderman (14807512)

“…This combined treatment modality using HIPEC with mitomycin C (MMC) for 90 minutes proved to be superior to systemic chemotherapy alone, but no benefit of adding HIPEC to CRS alone was shown using oxaliplatin-based HIPEC during 30 minutes. We investigated the impact of treatment temperature and duration as relevant HIPEC parameters for these two chemotherapeutic agents in representative preclinical models. …”

Image_7_Elevated temperatures and longer durations improve the efficacy of oxaliplatin- and mitomycin C-based hyperthermic intraperitoneal chemotherapy in a confirmed rat model for... by Roxan F. C. P. A. Helderman (14807512)

“…This combined treatment modality using HIPEC with mitomycin C (MMC) for 90 minutes proved to be superior to systemic chemotherapy alone, but no benefit of adding HIPEC to CRS alone was shown using oxaliplatin-based HIPEC during 30 minutes. We investigated the impact of treatment temperature and duration as relevant HIPEC parameters for these two chemotherapeutic agents in representative preclinical models. …”

Table_4_Multi-dimensional investigation and distribution characteristics analysis of gut microbiota of different marine fish in Fujian Province of China.XLSX by Hang Sun (202258)

“…Diversity and multivariate analyses showed that the patterns of the microbiota were significantly different in different fish species within the same habitat and E. akaara with five latitude regions. Mantel analysis showed that AN, SiO₃^2–, DO, and NO₂^– were the principal factors affecting the microbial community of E. akaara in the five habitats. …”

Table_1_Multi-dimensional investigation and distribution characteristics analysis of gut microbiota of different marine fish in Fujian Province of China.XLSX by Hang Sun (202258)

“…Diversity and multivariate analyses showed that the patterns of the microbiota were significantly different in different fish species within the same habitat and E. akaara with five latitude regions. Mantel analysis showed that AN, SiO₃^2–, DO, and NO₂^– were the principal factors affecting the microbial community of E. akaara in the five habitats. …”

Table_6_Multi-dimensional investigation and distribution characteristics analysis of gut microbiota of different marine fish in Fujian Province of China.XLSX by Hang Sun (202258)

“…Diversity and multivariate analyses showed that the patterns of the microbiota were significantly different in different fish species within the same habitat and E. akaara with five latitude regions. Mantel analysis showed that AN, SiO₃^2–, DO, and NO₂^– were the principal factors affecting the microbial community of E. akaara in the five habitats. …”

Data_Sheet_1_Multi-dimensional investigation and distribution characteristics analysis of gut microbiota of different marine fish in Fujian Province of China.docx by Hang Sun (202258)

“…Diversity and multivariate analyses showed that the patterns of the microbiota were significantly different in different fish species within the same habitat and E. akaara with five latitude regions. Mantel analysis showed that AN, SiO₃^2–, DO, and NO₂^– were the principal factors affecting the microbial community of E. akaara in the five habitats. …”

Table_3_Multi-dimensional investigation and distribution characteristics analysis of gut microbiota of different marine fish in Fujian Province of China.XLSX by Hang Sun (202258)

“…Diversity and multivariate analyses showed that the patterns of the microbiota were significantly different in different fish species within the same habitat and E. akaara with five latitude regions. Mantel analysis showed that AN, SiO₃^2–, DO, and NO₂^– were the principal factors affecting the microbial community of E. akaara in the five habitats. …”

Table_1_Antitumor Effects and Related Mechanisms of Ethyl Acetate Extracts of Polygonum perfoliatum L..doc by Qinglin Li (1841404)

“…It was further observed that PEC inhibited cancer cell growth, arrested cells at G2 phase, and induced apoptosis in vitro and suppressed tumor growth and angiogenesis in vivo in a dose- and time-dependent manner. …”

<b>CRTC1 in Mc4r-expressing cells is required for peripheral metabolism and systemic energy homeostasis</b> by Haruka Miyamori (11938689)

“…In this study, mice with CRTC1 deficiency in Mc4r-expressing cells exhibited 1) modest obesity, glucose intolerance, insulin resistance, hyperinsulinemia, and hyperlipidemia; 2) decreased systemic energy expenditure and thermogenesis; 3) suppression of melanocortin agonist-induced adaptation of energy expenditure and food intake; 4) impaired thermogenic programs and oxidative pathway in brown adipose tissue and skeletal muscle; and 5) enhanced lipogenic programs in the liver and white adipose tissue. …”

Too fast to stay on track? Shorter time to first anti-retroviral regimen is not associated with better retention in care in the French Dat’AIDS cohort by L. Cuzin (7353725)

“…We described time from (1) diagnosis to first specialized medical encounter, (2) from this encounter to ART initiation, (3) from diagnosis to first undetectable HIV viral load (VL). …”

Data_Sheet_1_Survival-Convolution Models for Predicting COVID-19 Cases and Assessing Effects of Mitigation Strategies.pdf by Qinxia Wang (9081194)

“…In China and South Korea, we predicted the entire disease epidemic using only early phase data (2–3 weeks after the outbreak). …”

image_4.jpeg by Jose Antonio Tavares de Albuquerque (4992938)

“…We evaluated Dectin-2 receptor signaling, phagocytosis, and cytokine secretion upon hyphal stimulation. …”

image_1.jpeg by Jose Antonio Tavares de Albuquerque (4992938)

“…We evaluated Dectin-2 receptor signaling, phagocytosis, and cytokine secretion upon hyphal stimulation. …”

image_7.jpeg by Jose Antonio Tavares de Albuquerque (4992938)

“…We evaluated Dectin-2 receptor signaling, phagocytosis, and cytokine secretion upon hyphal stimulation. …”

DataSheet1_High-Coverage Serum Metabolomics Reveals Metabolic Pathway Dysregulation in Diabetic Retinopathy: A Propensity Score-Matched Study.docx by Chengnan Guo (11023939)

“…</p><p>Methods: In this case-control study, we tested 613 serum metabolites in 69 pairs of type 2 diabetic patients (T2DM) with DR and propensity score-matched T2DM without DR via ultra-performance liquid chromatography-tandem mass spectrometry system. …”

image_3.jpeg by Jose Antonio Tavares de Albuquerque (4992938)

“…We evaluated Dectin-2 receptor signaling, phagocytosis, and cytokine secretion upon hyphal stimulation. …”