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98481
Image6_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.TIF
Published 2023“…We found that, while GCN2 phosphorylates eIF2α when nutrients are restricted, the ability to phosphorylate eIF2α is not required for changes in translation, nonsense-mediated decay, or lifespan associated with dietary restriction (DR). …”
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98482
Image3_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.TIF
Published 2023“…We found that, while GCN2 phosphorylates eIF2α when nutrients are restricted, the ability to phosphorylate eIF2α is not required for changes in translation, nonsense-mediated decay, or lifespan associated with dietary restriction (DR). …”
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98483
Data_Sheet_1_Machine learning approach to classifying declines of physical function and muscle strength associated with cognitive function in older women: gait characteristics base...
Published 2024“…In addition, support vector machine showed a Cog+MS+ and Cog–MS– classification problem with 93.6% accuracy when using all gait features and two selected features (left step time at PWS and gait asymmetry at SWS).…”
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98484
Data_Sheet_1_Machine learning approach to classifying declines of physical function and muscle strength associated with cognitive function in older women: gait characteristics base...
Published 2024“…In addition, support vector machine showed a Cog+MS+ and Cog–MS– classification problem with 93.6% accuracy when using all gait features and two selected features (left step time at PWS and gait asymmetry at SWS).…”
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98485
Data_Sheet_2_Machine learning approach to classifying declines of physical function and muscle strength associated with cognitive function in older women: gait characteristics base...
Published 2024“…In addition, support vector machine showed a Cog+MS+ and Cog–MS– classification problem with 93.6% accuracy when using all gait features and two selected features (left step time at PWS and gait asymmetry at SWS).…”
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98486
Data_Sheet_2_Machine learning approach to classifying declines of physical function and muscle strength associated with cognitive function in older women: gait characteristics base...
Published 2024“…In addition, support vector machine showed a Cog+MS+ and Cog–MS– classification problem with 93.6% accuracy when using all gait features and two selected features (left step time at PWS and gait asymmetry at SWS).…”
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98487
Deregulation of cell growth and apoptosis in UV-induced melanomagenesis
Published 2020“…More interestingly, p16 mutant cells increased their resistance to apoptosis at high UVB-dose, associated with decreased Bax and increased Bcl2 expression. Thus, mutant-p16 appears to dictate a deregulation of cell cycle and increased resistance to apoptosis in melanoma cells. …”
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98488
Altered Expression of Polycomb Group Genes in Glioblastoma Multiforme
Published 2013“…We validated the aberrant expression of CBX6, CBX7, CBX8 and EZH2 in GBM cell lines by Western blotting and qRT-PCR, and further the aberrant expression of CBX6 in GBM tissue samples by immunohistochemical staining. …”
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98489
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98490
Table_1_Racialized Pandemic: The Effect of Racial Attitudes on COVID-19 Conspiracy Theory Beliefs.DOCX
Published 2022“…<p>As national and international health agencies rushed to respond to the global spread of a novel coronavirus (SARS-CoV-2, commonly known as COVID-19), one challenge these organizations faced was the spread of misinformation and conspiracy theories about the virus. …”
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98491
Data_Sheet_1_Racialized Pandemic: The Effect of Racial Attitudes on COVID-19 Conspiracy Theory Beliefs.ZIP
Published 2022“…<p>As national and international health agencies rushed to respond to the global spread of a novel coronavirus (SARS-CoV-2, commonly known as COVID-19), one challenge these organizations faced was the spread of misinformation and conspiracy theories about the virus. …”
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98492
Modeling Retinal Degeneration Using Patient-Specific Induced Pluripotent Stem Cells
Published 2011“…It is well known that the disease is caused by rod photoreceptor degeneration; however, it remains incurable, due to the unavailability of disease-specific human photoreceptor cells for use in mechanistic studies and drug screening. We obtained fibroblast cells from five RP patients with distinct mutations in the <em>RP1</em>, <em>RP9</em>, <em>PRPH2</em> or <em>RHO</em> gene, and generated patient-specific induced pluripotent stem (iPS) cells by ectopic expression of four key reprogramming factors. …”
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98493
Heme Oxygenase-1 Protects Retinal Endothelial Cells against High Glucose- and Oxidative/Nitrosative Stress-Induced Toxicity
Published 2012“…Retinal endothelial cells were exposed to elevated glucose, nitric oxide (NO) and hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>). Cell viability and apoptosis were assessed by MTT assay, Hoechst staining, TUNEL assay and Annexin V labeling. …”
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98494
Effect of BaP1 and CsH1 on type IV collagen from vascular BM on mouse cremaster muscle.
Published 2016“…The images show a decrease in fluorescence intensity for type IV collagen in BM of arterioles, capillaries, and PCV of treated tissues as compared to control. …”
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98495
Results from conditional inference forest analysis of the presence/absence of spruce beetle infestation with climate and forest structure data in the Southern Rocky Mountain study...
Published 2015“…<p>(A) Conditional variable importance for the five biophysical variables used to model the occurrence of spruce beetle infestation across the Southern Rocky Mountain study region. …”
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98496
SEAwise report on effects of spatial management measures suggested in SEAwise to safeguard species, habitats and choke species on fisheries selectivity and fuel cost
Published 2024“…Approximately a 10% reduction in the overall catch was anticipated under the RCP8.5 2060 climate scenario. …”
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98497
Loss of parasympathetic cholinergic neurons innervating the liver.
Published 2024“…Unpaired <i>t</i> test, **<i>p</i> < 0.01. (D) Images showing a lack of vAChT-positive nerve terminals in the liver parenchyma of ChAT<sup>Cre + AAVrg-FLEX-dtA</sup> mice (right panel). …”
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98498
DataSheet_1_Adapting Rapid Diagnostic Tests to Detect Historical Dengue Virus Infections.pdf
Published 2021“…Dengue experts recommend that these assays be highly specific (≥98%) to avoid erroneously vaccinating individuals without prior DENV infection, as well as be sensitive enough (≥95%) to detect individuals with a single prior DENV infection. We evaluated one existing and two newly developed anti-flavivirus RDTs using samples collected >6 months post-infection from individuals in non-endemic and DENV and ZIKV endemic areas. …”
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98499
Presentation_1_Adapting Rapid Diagnostic Tests to Detect Historical Dengue Virus Infections.pdf
Published 2021“…Dengue experts recommend that these assays be highly specific (≥98%) to avoid erroneously vaccinating individuals without prior DENV infection, as well as be sensitive enough (≥95%) to detect individuals with a single prior DENV infection. We evaluated one existing and two newly developed anti-flavivirus RDTs using samples collected >6 months post-infection from individuals in non-endemic and DENV and ZIKV endemic areas. …”
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98500
Composition and Localization of Lipids in <em>Penaeus merguiensis</em> Ovaries during the Ovarian Maturation Cycle as Revealed by Imaging Mass Spectrometry
Published 2012“…Further, by using gas chromatography, we found that (1) FAs 14∶0, 16∶1, 18∶1, 18∶2, 20∶1, and 22∶6 proportionally increased as ovarian development progressed to more mature stages; (2) FAs 16∶0, 18∶0, 20∶4, and 20∶5 proportionally decreased; and (3) FAs 15∶0, 17∶0, and 20∶2 remained unchanged. …”