Here, we present results from our block copolymer model, which simulates the chromosomes of the <i>Drosophila</i> genome. by Gaurav Bajpai (3704704)

“…Comparing this to the contact map for the same block copolymer model in the absence of binding to the lamina in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011142#pcbi.1011142.g005" target="_blank">Fig 5c</a>, we observe a smaller probability of contact in the off-diagonal regions. …”

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not? by Styliani Fragki (10691290)

Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage by Lucia Reh (546554)

“…To enable this, properties that render HIV-1 envelopes (Env) capable of eliciting bnAb responses need to be defined. Here, we followed the evolution of the V2 apex directed bnAb lineage VRC26 in the HIV-1 subtype C superinfected donor CAP256 to investigate the phenotypic changes of the virus populations circulating before and during the early phases of bnAb induction. …”

The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis by Nao Itai (5954666)

Subjects:

LCI measurement bias due to decreased ambient pressure settings. by Selina Summermatter (768995)

Top 5 templates of CNN1 isoform 2 by PHYRE2 tool. by Muhammad Bilal Azmi (14519913)

“…Molecular interactions of CNN1 with progesterone were investigated through LigPlot 2D. Further, molecular docking experimentation of CNN1 showed the significant interactions at S102, L105, A106, K123, Y124 with five selected PTB-drugs, Allylestrenol (-7.56 kcal/mol), Hydroxyprogesterone caproate (-8.19 kcal/mol), Retosiban (-9.43 kcal/mol), Ritodrine (-7.39 kcal/mol) and Terbutaline (-6.87 kcal/mol). …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

Optical Effects of <i>S</i>-Oxidation and M^<i>n</i>+ Binding in <i>meso</i>-Thienyl Dipyrrin Systems and of Stepwise Bromination of 4,4-Difluoro-8-(2,5-dibromo-3-thienyl... by Shin Hei Choi (2190841)

“…<i>meso</i>-Thienyl group properties were revealed through the use of 3,4,4-triphenyl-8-(thienyl)-4-bora-3<i>a</i>,4<i>a</i>-diaza-<i>s</i>-indacene; Cu²⁺ addition resulted in smooth absorption decreases which were modeled to support 1:1 substrate:M²⁺ binding; for Hg²⁺ 1:2 substrate:M²⁺ binding was found. …”

For most sites, observed abundance decreases with size class. by Sarah L. Becker (6631253)

Image_2_SIRT1 haplo-insufficiency results in reduced cortical bone thickness, increased porosity and decreased estrogen receptor alpha in bone in adult 129/Sv female mice.tif by Hanna Artsi (777390)

“…</p>Methods<p>To investigate the mechanisms of gender differences in SIRT1 skeletal effect, we investigated femoral and vertebral cortical and cancellous bone in global Sirt1 haplo-insufficient 129/Sv mice aged 2,7,12 months lacking Sirt1 exons 5,6,7 (Sirt1^+/Δ) and their wild type (WT) counterparts.…”

Identifying radiation-induced survivorship syndromes affecting bowel health in a cohort of gynecological cancer survivors by Gunnar Steineck (226792)

“…<div><p>Background</p><p>During radiotherapy unwanted radiation to normal tissue surrounding the tumor triggers survivorship diseases; we lack a nosology for radiation-induced survivorship diseases that decrease bowel health and we do not know which symptoms are related to which diseases.…”

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)

Discovery of <i>N</i>‑((3<i>S</i>,4<i>S</i>)‑4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl‑1<i>H</i>‑pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous Toxicity by Jinxin Che (791250)