Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient Hearts by Alexia Vite (462320)

“…</p> <p>Methods and Results</p><p>We examined plakophilin-2, desmoglein-2, desmocollin-2, plakoglobin and β-catenin protein expression levels from seven independent ARVD/C heart samples compared to two ischemic, five dilated cardiomyopathy and one healthy heart sample as controls. …”

ShakB(N+16) increases, and ShakB(N) decreases, NB coupling. by Sami H. Jezzini (650703)

Decreased mTEC to cTEC ratios in the absence of mTORC1/Raptor. by Hong-Xia Wang (288934)

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

CMV infection decreases integrity of polarized HCoEpiC and increases barrier permeability. by Ekaterina Maidji (3797899)

UV-B exposure decreased the production of porphyrins in bacteria isolated from human faces. by Yanhan Wang (124296)

Celecoxib decreases the viability of MDA-MB-231-and MDA-MB-435-stable transfectants by Takeshi Sugimoto (84349)

GBE did not modify cell morphology but decreased reactive oxygen species (ROS) levels. by Virginie Rhein (243241)

“…<b>C</b>) Mitochondria-associated ROS levels measured after incubation with DHR (DHR fluorescence units/1×10⁵ cells). ROS levels showed a trend to be increased in APP cells compared to control cells (⁽*⁾p = 0.082, unpaired student's t-test, n = 11, values represent the means ± S.E.). …”

Behavioral deficits correlate with decreasing PO₂ in cortical grey matter. by Thomas W. Johnson (437931)

AR inhibition decreases airway hyper-responsiveness in the OVA-challenged chronic asthmatic mice. by Umesh C. S. Yadav (358228)

Decreased sensitivity to apoptosis-related proteins in late passage <i>-/</i>- MEF cells. by Satoshi Miuma (117853)

Reishi decreases EIF4F complex levels and protein synthesis in IBC cells. by Ivette J. Suarez-Arroyo (383847)

Decreased cytokine production by moDCs upon TLR stimulation when preincubated with NSAIDs. by Tonke K. Raaijmakers (13955749)

Rapamycin decreases Schwann cell markers, whereas statin induces Schwann cell markers. by Andrea Preitschopf (629851)

Ethanol intoxication combined with burn injury decreases miRNA155 expression in T cells. by Xiaoling Li (129705)

Aspirin decreases expression of NFκB and β-catenin in colon cancer cells. by Satya Pathi (301408)

“…<p>Decreased p65/p50 in RKO (A) and SW480 (B) cells. Cells were treated for 48 hr with 5 or 10 mM, and whole cell, nuclear and cytosolic extracts were analyzed by western blot analysis as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0048208#s3" target="_blank">Experimental Procedures</a>. …”

DHA combined with the glycolysis inhibitor decreases cell viability and induces apoptosis in NSCLC cells. by Yan-jun Mi (264759)

Macrophage depletion with clodronate decreases the expression of splenic BMP4 in tumor-bearing mice. by Min Liu (45756)

Epithelial-specific disruption of <i>Meis1</i> decreased epidermal stem cells. by Kazuhiro Okumura (566659)