MMV291 analogues interfere with actin polymerisation in the presence of profilin in vitro. by Madeline G. Dans (14193815)

“…<b>(B)</b> Upon addition of PfPFN, actin sedimentation decreased to 21 ± 1% with DMSO treatment. All MMV291 analogues, <i>S</i>-MMV291, <i>R</i>-MMV291, <i>S</i>-W936, <i>R</i>-W936, <i>S</i>-W414, and <i>S</i>-W827, decreased the amount of actin in the pellet further to 11 ± 1%, 15 ± 2%, 8 ± 2%, 10 ± 4%, 9 ± 4%, and 5 ± 2%, respectively. …”

Image 3_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... by Xinchi Shang (11982840)

“…Disorders of arachidonic acid metabolism led to the release of proinflammatory metabolites (such as thromboxane A2 and prostaglandin J2), and decreased levels of reduced glutathione.…”

Table 1_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... by Xinchi Shang (11982840)

“…Disorders of arachidonic acid metabolism led to the release of proinflammatory metabolites (such as thromboxane A2 and prostaglandin J2), and decreased levels of reduced glutathione.…”

Image 4_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... by Xinchi Shang (11982840)

“…Disorders of arachidonic acid metabolism led to the release of proinflammatory metabolites (such as thromboxane A2 and prostaglandin J2), and decreased levels of reduced glutathione.…”

Image 1_Chronic hexavalent chromium exposure induces oxidative stress-mediated molecular cascades in Thymallus grubii gills: evidence from integrated transcriptomics and metabolomi... by Xinchi Shang (11982840)

“…Disorders of arachidonic acid metabolism led to the release of proinflammatory metabolites (such as thromboxane A2 and prostaglandin J2), and decreased levels of reduced glutathione.…”

An Invasive Plant Promotes Its Arbuscular Mycorrhizal Symbioses and Competitiveness through Its Secondary Metabolites: Indirect Evidence from Activated Carbon by Yongge Yuan (562079)

“…Whether these secondary metabolites affect the invasive plant itself, directly or indirectly through microorganisms, however, has not been well documented. Here we tested whether activated carbon (AC), a well-known absorbent for secondary metabolites, affect arbuscular mycorrhizal (AM) symbioses and competitive ability in an invasive plant. …”

Changes in late-latency auditory evoked potentials after tinnitus suppression using auditory stimulation by Nastaran Ranjbar (3698143)

AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure by Chang Sik Park (142203)

“…We found that phospho-RyR2, phospho-CaMKII, phospho-p38 MAPK, and phospho-PLB were significantly upregulated by HRC-KD in TAC-FH. …”

Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes by Nivedita Hegdekar (6563744)

“…</p> <p><b>Abbreviations:</b><i>Becn1</i>/BECN1, beclin 1, autophagy related; CCI, controlled cortical impact; <i>Cybb</i>/CYBB/NOX2: cytochrome b-245, beta polypeptide; DAMP, danger/damage-associated molecular patterns; <i>Il1b</i>/IL1B/Il-1β, interleukin 1 beta; LAP, LC3-associated phagocytosis; <i>Map1lc3b</i>/MAP1LC3/LC3, microtubule-associated protein 1 light chain 3 beta; <i>Mefv</i>/MEFV/TRIM20: Mediterranean fever; <i>Nos2</i>/NOS2/iNOS: nitric oxide synthase 2, inducible; <i>Nlrp3</i>/NLRP3, NLR family, pyrin domain containing 3; <i>Sqstm1</i>/SQSTM1/p62, sequestosome 1; TBI, traumatic brain injury; <i>Tnf</i>/TNF/TNF-α, tumor necrosis factor; <i>Ulk1</i>/ULK1, unc-51 like kinase 1.…”

Long-term trends at CARICOMP seagrass stations, including observations on disturbances. by Brigitta I. van Tussenbroek (530025)

“…<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0090600#pone.0090600-Fourqurean5" target="_blank">[49]</a>, 3. …”

Effect of temporal control of the Raf/MEK/ERK pathway on PC12 neurite outgrowth. by Kai Zhang (102844)

“…When the off-time exceeded 45 min, neurite length gradually decreased. ***p<0.001. (C) The average neurite length induced by intermittent light stimulation with a 45-min on-time and various off-times at 27, 45, 75, 135, 315 min. …”

Supplementary Material for: Body Mass Index Change and Hospitalization Risk in Elderly Hemodialysis Patients: Results from Japanese Dialysis Outcomes and Practice Patterns Study by Sumida K. (3968612)

“…<b><i>Results:</i></b> During a median follow-up of 1.2 years, we noted 1,028 incident hospitalizations for any cause, including 275 and 753 hospitalizations for cardiovascular and noncardiovascular causes, respectively. …”

Propofol inhibits burn injury-induced hyperpermeability through an apoptotic signal pathway in microvascular endothelial cells by K.Y. Tian (6515141)

“…Compared with a sham treatment group, intrinsic apoptotic signaling activation - indicated by Bax overexpression, Bcl-2 downregulation, Δψm reduction, decreased intracellular ATP level, increased cytosolic cytochrome C and smac, and caspase-3 activation - was observed in the vehicle group. …”

Granola consumption with multiple prebiotics in Japanese participants increases <i>Bifidobacterium</i> abundance and improves stress and subjective sleepiness by Hiroyuki Sasaki (20851130)

“…Stress levels were assessed by administering the Brief Job Stress Questionnaire and Profile of Mood States 2nd edition (POMS2). Gut microbiota composition was analyzed using 16S rDNA sequencing.…”

Dataset and R code for Humann-Guilleminot et al. - Dose-dependent effects of cadmium on food consumption, mass, and bioaccumulation in the moth <i>Spodoptera littoralis.</i> by Ségolène Humann-Guilleminot (20908844)

“…Adverse effects were noted at a sublethal dose of 31.25 µg/g, with particularly severe outcomes at the highest lethal doses ranging from 0.5 to 50 mg/g, where 100% mortality was observed after treatment. …”

DataSheet_1_Preliminary Safety and Potential Effect of 6B11-OCIK Adoptive Cell Therapy Against Platinum-Resistant Recurrent or Refractory Ovarian Cancer.docx by Hongyan Cheng (445898)

“…We found that 6B11-OCIK treatment was safe and well tolerated after five cycles of intravenous infusion with an initial dose of 1–2×10⁹ cells and a dose-climbing strategy. …”

Image_1_Preliminary Safety and Potential Effect of 6B11-OCIK Adoptive Cell Therapy Against Platinum-Resistant Recurrent or Refractory Ovarian Cancer.tif by Hongyan Cheng (445898)

“…We found that 6B11-OCIK treatment was safe and well tolerated after five cycles of intravenous infusion with an initial dose of 1–2×10⁹ cells and a dose-climbing strategy. …”

Image_3_Preliminary Safety and Potential Effect of 6B11-OCIK Adoptive Cell Therapy Against Platinum-Resistant Recurrent or Refractory Ovarian Cancer.tif by Hongyan Cheng (445898)

“…We found that 6B11-OCIK treatment was safe and well tolerated after five cycles of intravenous infusion with an initial dose of 1–2×10⁹ cells and a dose-climbing strategy. …”

Image_4_Preliminary Safety and Potential Effect of 6B11-OCIK Adoptive Cell Therapy Against Platinum-Resistant Recurrent or Refractory Ovarian Cancer.tif by Hongyan Cheng (445898)

“…We found that 6B11-OCIK treatment was safe and well tolerated after five cycles of intravenous infusion with an initial dose of 1–2×10⁹ cells and a dose-climbing strategy. …”

The Effect of PLGA Conduit Loading Insulin-like Growth Factor 1 Modified by Collagen-Binding Domain on Peripheral Nerve Injury of Rats. by Jian`an Li (5221370)

“…</p> Figure 4 presents the SFI score. There is a gradual decrease in the SFI from week 1 to week 3. …”