TK1 protein levels do not reflect p-ERK attenuation following inhibition of ^V600EBRAF inhibition in COLO 205 cells. by Eliot T. McKinley (390272)

“…<p>COLO 205 cells were collected 48 hours of PLX 4032 exposure at 10 nM, 100 nM, 500 nM, 1 µM, or 5 µM. (<b>A</b>) Western blot analysis demonstrated target inhibition of p-MEK despite increased p-ERK levels. …”

Figure 3. Difference and entropy-change graphs for networks shown in Figure 2. by Andrey Rzhetsky (42928)

“…</p> <p>The nodes that we mentioned in the text have the following coordinates: <i>WNT1 (6b), HBP1 (6b), EMX2 (6b), SRF (3b), SP1 (3b), TP53 (4b), PSEN1 (5c)</i>.…”

Dysregulated genes in <i>BRIP1</i>-knockdown cells during acinar morphogenesis (ANOVA, <i>P</i><0.05; fold change ≥5.0). by Kazuhiro Daino (203837)

Image1_The Activation of PDGFRβ on Mononuclear Stromal/Tumor Cells in Giant Cell Tumor of Bone After Denosumab Treatment. An Immunohistochemical Study of Five Cases.TIF by Imre Antal (733427)

“…<p>Due to the relatively high recurrence rate and the destructive nature of the tumor, the treatment of giant cell tumor is still a challenge. Denosumab appeared to be a promising candidate as a therapeutic drug. …”

Schematic representation of the mechanisms involved in ALD-induced decrement of expression of cldn-5 in GL and, cldn-2 and occldn in PT, and increased expression of cldn-4 and -8 i... by Eduardo Molina-Jijón (4020464)

“…<p>(A) In GL, diabetes-induced ALD promotes glomerular damage, evaluated by decreased expression of nephrin and WT1, and oxidative stress, which may be associated to decreased cldn-5 expression and proteinuria. …”

Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression by Burge Ulukan (9541116)

“…Given the importance of the prometastatic activity of TG2 in RCC, in the present study, we aim to investigate the relative contribution of TG2’s transamidase and guanosine triphosphate (GTP)-binding/GTPase activity in the cell migration, invasion, EMT, and cancer stemness of RCC. …”

Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression by Burge Ulukan (9541116)

“…Given the importance of the prometastatic activity of TG2 in RCC, in the present study, we aim to investigate the relative contribution of TG2’s transamidase and guanosine triphosphate (GTP)-binding/GTPase activity in the cell migration, invasion, EMT, and cancer stemness of RCC. …”

Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression by Burge Ulukan (9541116)

“…Given the importance of the prometastatic activity of TG2 in RCC, in the present study, we aim to investigate the relative contribution of TG2’s transamidase and guanosine triphosphate (GTP)-binding/GTPase activity in the cell migration, invasion, EMT, and cancer stemness of RCC. …”

A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction by Nobuo Watanabe (845921)

“…<div><p>Podoplanin, a transmembrane glycoprotein, is overexpressed in certain types of tumors and induces platelet aggregation by binding to C-type lectin-like receptor 2 (CLEC-2) on the platelet membrane. Activated platelets release granule components, which in turn, trigger epithelial-mesenchymal transition and confer invasive capacity to the tumor cells. …”

Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression by Burge Ulukan (9541116)

“…Given the importance of the prometastatic activity of TG2 in RCC, in the present study, we aim to investigate the relative contribution of TG2’s transamidase and guanosine triphosphate (GTP)-binding/GTPase activity in the cell migration, invasion, EMT, and cancer stemness of RCC. …”

Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression by Burge Ulukan (9541116)

“…Given the importance of the prometastatic activity of TG2 in RCC, in the present study, we aim to investigate the relative contribution of TG2’s transamidase and guanosine triphosphate (GTP)-binding/GTPase activity in the cell migration, invasion, EMT, and cancer stemness of RCC. …”

Table_1_Profiles of Rho, Opn4, c-Fos, and Birc5 mRNA expression in Wistar rat retinas exposed to white or monochromatic light.DOCX by Natalia Ziółkowska (550789)

“…Blue and green light exposure markedly decreased expression of Rho and Opn4 mRNA and increased expression of Birc5 and c-Fos mRNA (P < 0.05). …”

Image_1_Profiles of Rho, Opn4, c-Fos, and Birc5 mRNA expression in Wistar rat retinas exposed to white or monochromatic light.TIF by Natalia Ziółkowska (550789)

“…Blue and green light exposure markedly decreased expression of Rho and Opn4 mRNA and increased expression of Birc5 and c-Fos mRNA (P < 0.05). …”

Image_2_Profiles of Rho, Opn4, c-Fos, and Birc5 mRNA expression in Wistar rat retinas exposed to white or monochromatic light.TIF by Natalia Ziółkowska (550789)

“…Blue and green light exposure markedly decreased expression of Rho and Opn4 mRNA and increased expression of Birc5 and c-Fos mRNA (P < 0.05). …”

(A) Bath application of 2 by Alexander V Garger (2911)

“…This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.</p>5 mM IBMX produced a characteristic depolarization of photoreceptors () that was diminished following intracellular pressure injection sufficient to inhibit the light response from a microelectrode containing 25 mM GtetP (). …”

DataSheet1_miR-513c-5p Suppression Aggravates Pyroptosis of Endothelial Cell in Deep Venous Thrombosis by Promoting Caspase-1.docx by Chu Chu (6210905)

“…Collectively, these results revealed that the pyroptosis of VECs induced by decreased miR-513c-5p was involved in DVT progression and indicated a potential therapeutic strategy of targeting the miR-513c-5p/caspase-1/GSDMD signal axis for DVT management.…”

Vitexin attenuates lipopolysaccharide-induced acute lung injury by controlling the Nrf2 pathway by Ying Lu (66401)

“…Moreover, Vitexin activated nuclear factor erythroid-2-related factor 2 (Nrf2), and increased the activity of its target gene heme oxygenase (HO)-1. …”

Video_5_Local Delivery of Taxol From FGL-Functionalized Self-Assembling Peptide Nanofiber Scaffold Promotes Recovery After Spinal Cord Injury.MP4 by Zhiyong Xiao (2521051)

“…The local delivery of Taxol from FGLmx/Taxol significantly decreased glial scarring and increased the number of nerve fibers compared with the use of FGLmx and 5% glucose. …”

FOXO1 Binds to −125/−91 of the <i>Fshb</i> Promoter. by Chung Hyun Park (665717)

Nitrone Cycloadditions to 1,2-Diphenylcyclopropenes and Subsequent Transformations of the Isoxazolidine Cycloadducts by Vyacheslav V. Diev (1967635)