Prohibitin2 knockdown decreases glioma malignant phenotypes and radio-resistance by inhibiting mitophagy by Xuefei Xue (16496943)

“…Additionally, PHB2 regulated the expression of PGAM5 and PINK1 by directly binding to PARL.</p> <p>Our findings revealed that PHB2 knockdown decreased glioma malignant phenotypes and radio-resistance by inhibiting mitophagy <i>via</i> PARL–PGAM5–PINK1–Parkin pathway. …”

Decreased exploratory activity in the second day trial in offspring of exercised mothers indicates habituation. by Sérgio Gomes da Silva (846060)

“…For both the 5- and 10-min investigation periods, a significant decrease in peripheral locomotion was detected in the EX group between the first and second trial (*p < 0.05; one-way ANOVA with repeated measures; Bonferroni post hoc). …”

Presentation_1_mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an... by Jana Sophia Buhre (12295230)

“…</p>Objective<p>However, the impact of these new vaccine formats with unclear effects on the long-term Ab response – including isotype, subclass, and their type of Fc glycosylation – is less explored.</p>Methods<p>Here, we analyzed anti-S Ab responses in blood serum and the saliva of SARS-CoV-2 naïve and non-hospitalized pre-infected subjects upon two vaccinations with different mRNA- and adenovirus-based vaccine combinations up to day 270.…”

Compressive strength as a function of glass fiber layers modified GFRPs. by Shaban Gul (14309526)

Time course of body weight (A) and cumulative food intake (B). by Toru Kuriyama (16631992)

When unbound to CRL4, BK channel α subunit is redirected to SCF^Fbxo7 for proteasomal degradation. by Tianyu Song (4797417)

Effects of 5-Aza-dc and alcohol on DNMTs and Ntf3/TrkC expressions in the mPFC. by Xiaomeng Qiao (3139755)

“…<p>Fig 5A shows representative immunoblots and total protein image. 5-Aza-dc decreased the protein level of DNMT1 (B), whereas it reversed the alcohol-induced overexpression of DNMT3A (C) and DNMT3B (D). 5-Aza-dc prevented the Ntf3 reduction induced by chronic alcohol exposure (E) but had no effect on TrkC (F). …”

Nepmucin/CD300LG expression is decreased in tumors and tumor-draining lymph nodes. by Eiji Umemoto (1637)

The fraction of completely new links relative to the total number of links, , decreases over time. by Jesper Bruun (662385)

Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells by Yuki Yasumoto (685821)

“…When GSCs were treated with 20 μM cerulenin, a pharmacological inhibitor of FASN, their proliferation and migration were significantly suppressed and <i>de novo</i> lipogenesis decreased. Furthermore, following cerulenin treatment, expression of the GSC markers nestin, Sox2 and fatty acid binding protein (FABP7), markers of GCSs, decreased while that of glial fibrillary acidic protein (GFAP) expression increased. …”

Silencing of Cav-1 expression decreases the IR-induced formation of BRCA1 foci. by Hua Zhu (131619)

Supplementary Material for: Dietary Fiber Consumption Decreases the Risks of Overweight and Hypercholesterolemia in Japanese Children by Shinozaki K. (4154458)

“…<b><i>Results:</i></b> Total fiber intake decreased the risks of overweight and high total cholesterol (OR Quintile 5 vs. …”

DP8α LPL and PBL, and the PBL reactivity to F, are decreased in patients with IBD. by Guillaume Sarrabayrouse (58505)

miR-124 decreases cell proliferation in 2D and 3D cultures. by Alexa Tenga (2161780)

“…As a result, Nur77 mRNA levels were significantly decreased (<i>p</i> < 0.0001). …”

Inhibition of the <i>Hedgehog</i> pathway leads to decreased ostegenesis <i>in vitro</i>. by Emily R. Nelson (247130)

“…N = 3, *p<0.01. (A) Wild-type, CD-1 palates treated with cyclopamine for 2 days exhibited a decrease in osteogenic markers <i>Alp</i>, <i>Runx2</i>, and <i>Col1a1</i> by qRT-PCR, with a significant decrease in <i>Col1a1</i>. …”

A Practical, Fast, and High-Yielding Aziridination Procedure Using Simple Cu(II) Complexes Containing N-Donor Pyridine-Based Ligands by Fabian Mohr (1457233)

“…<i>Four-coordinate</i> dichlorocopper(II) complexes derived from di(2-pyridyl)methanes or pyridine itself exhibit high catalytic activity in aziridination of regular olefins with PhINTs in weakly coordinating chloroform in the presence of 1−2 equiv of NaBAr^F₄ (BAr^F₄^- = tetra[3,5-di(trifluoromethyl)phenyl]borate). High yields of aziridines exceeding 90% can be obtained with a 1:1 olefin/PhINTs ratio and 1−5 mol % catalyst loading for such reactive olefins as styrene, tri- and tetramethylethylene. …”

A Practical, Fast, and High-Yielding Aziridination Procedure Using Simple Cu(II) Complexes Containing N-Donor Pyridine-Based Ligands by Fabian Mohr (1457233)

“…<i>Four-coordinate</i> dichlorocopper(II) complexes derived from di(2-pyridyl)methanes or pyridine itself exhibit high catalytic activity in aziridination of regular olefins with PhINTs in weakly coordinating chloroform in the presence of 1−2 equiv of NaBAr^F₄ (BAr^F₄^- = tetra[3,5-di(trifluoromethyl)phenyl]borate). High yields of aziridines exceeding 90% can be obtained with a 1:1 olefin/PhINTs ratio and 1−5 mol % catalyst loading for such reactive olefins as styrene, tri- and tetramethylethylene. …”

Table1_Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis.DOCX by Michael Horckmans (14206388)

“…P2Y₄ knockout (KO) in mice protects against myocardial infarction and is characterized by increased adiponectin secretion by adipocytes, and decreased cardiac inflammation and permeability under ischemic conditions. …”

Electroretinogram (ERG) recordings from 6-, 9-, and 12-month mice show deficits in 5xFAD photoreceptors. by Shaylah McCool (20818280)

“…Two-way ANOVA with Tukey’s multiple comparisons post-hoc test was used for analysis. (C) Quantification of A- and B-wave amplitudes at the highest intensity stimulus (3.0000 cd * s/m²) shows the significant increase and decrease in retinal function in the 6- and 9-month 5xFAD mice, respectively, analyzed by two-way ANOVA with Tukey’s multiple comparisons. …”

Disaccharide fingerprint of CS/DS from different organs of mice with decreasing epimerase expression. by Xanthi N. Stachtea (816480)