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461
Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter...
Published 2022“…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…”
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462
Dynamic Imaging of Hydrate Specific Area Evolution during Xenon Hydrate Formation
Published 2020“…During hydrate formation and dissociation, full 3D images are acquired at a time resolution of 45 seconds and a spatial resolution of 5.38 ?…”
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463
High temperature thermal stability of innovative nanostructured thin coatings for advanced tooling
Published 2014“…Three different thin hard nitrogen-rich coatings were mechanically, microstructurally, and thermally characterized: A 2.5 micron-thick CrN-NbN, a 11.7 micron-thick TiAlN, and a 2.92 micron-thick AlTiCrxNy. …”
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464
Origanum Syriacum Inhibits Proliferation, Migration, Invasion and Induces Differentiation of Human Aortic Smooth Muscle Cells
Published 2014“…The optimum concentration, 0.2 mg/ml, significantly decreased HASMCs viability at 24 and 72 hours by 52.5 ± 10.39% and 47.6 ± 9.83% compared to control, respectively. …”
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465
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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466
Functionalization of silica-coated magnetic nanoparticles as powerful demulsifier to recover oil from oil-in-water emulsion
Published 2021“…The Fe–Si-MNP exhibited excellent %Soil, reliable stability, and high magnetization values ranging between 46.1 and 80.2 emu/g. adding a 5 nm silica layer on the surface of the Fe–Si-MNP (i.e., Fe–Si-1) protected them from oxidation conditions, extended their service life, and achieved a %Soil of ∼96.3%. …”
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467
Association between Insulin and Nitric Oxide in Human Retinal Microvascular Endothelial Cells in vitro
Published 2016“…This study demonstrated that hyperglycemia causes an increase in ROS/oxidative stress and apoptosis, while insulin promotes a significant decrease in ROS and apoptosis. eNOS mediated NO production increases with hyperglycemia but remarkably decreases with insulin treatment after 1 hour, 2 hours and 4 hours. …”
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468
Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…Municipal solid waste management is one of the major challenges facing Qatar with more than 2.5 million tons of municipal solid waste each year, a very high waste generation rate in a country with small land mass. …”
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469
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470
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…Beyond its enzymatic role, CBS contributes to hydrogen sulfide (H2S) production, a gaseous signaling molecule with diverse regulatory functions within the vascular, nervous, and immune systems. …”
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471
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472
Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes
Published 2021“…In contrast, expected changes in atmospheric N deposition will decrease the mid-term mass loss of high-quality litter by 1.4-2.2% and that of low-quality litter by 0.9-1.5% in the temperate biome. …”
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473
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries
Published 2022“…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …”
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474
Smoking cessation counseling in Qatar: Community pharmacists' attitudes, role perceptions and practices
Published 2012“…Main outcome measures: Qatar community pharmacists' smoking cessation practices, their attitudes toward tobacco use, smoking cessation and smoking cessation counseling and their perceived barriers for smoking cessation counseling. Results: Over 5 months, we collected 127 surveys (40 % response rate). …”
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475
CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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476
Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
Published 2024“…These factors included 2.5nM tumor necrosis factor-alpha (TNFα), 20 ng/ml interleukin-6 (IL-6), 10 micromole 4-hydroxynonenal (4HNE), and high insulin (HI) at a concentration of 100nM. …”
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477
Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis
Published 2023“…We found that 159 patients were matched in group I, 505, and 639 were in groups II and III of AAS, respectively. …”
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478
Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
Published 2016“…The pH range for the Clinoleic formulations (7.1–7.5) was slightly higher than that of the Intralipid formulations (6.5–6.9). …”
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479
USING EMBEDDED MACHINE LEARNING IN THE PHYSICAL WORLD TO DETECT TOXICITY IN SPOKEN LANGUAGE
Published 2023“…Detecting toxicity in the physical world is challenging due to the difficulty of integrating AI-capable computers into the environment. We propose a lightweight transformer model based on wav2vec2.0 and optimize it using quantization and knowledge distillation techniques. …”
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480
Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
Published 2019“…The formulation of silymarin-HSA nanoplex showed a spherical shape with an average diameter between 50 nm and 150 nm, hydrodynamic radius of 188.3 nm, zeta potential of −26.6 mV, and a drug loading of 97.3%. …”
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