Figure S4 from miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense by Marina Pajic (132629)

“…<p>RT + miR-139-5p mimic-treated tumours had significantly decreased Ki-67-positive cells, and significantly increased phospho-H2AX- and caspase-3-positive cells compared to control mimic-treated tumours (A-C). phospho-H2AX immunostaining was confined to the tumour field that received the radiation; the kidneys and liver, non-target organs that were not within the radiation field but which accumulated miRNA mimic did not have detectable phospho-H2AX expression (D-E).…”

Therapeutic efficacy of Clrn1 re-expression in Müller glia depends on expression level. by Hannah J. T. Nonarath (20861735)

“…<p>(a) Retinal images of 7 dpf wild-type (upper rows) and <i>clrn1</i>^<i>-/-</i> mutant (lower rows) zebrafish expressing different transgenes (column labels) raised in control lighting conditions (right) or treated from 5-7 dpf with 3500 lux for 48 hours (left, light stress). …”

DataSheet_1_Three-Dimensional Modeling of Thyroid Hormone Metabolites Binding to the Cancer-Relevant αvβ3 Integrin: In-Silico Based Study.pdf by Dror Tobi (78594)

“…While computational data on TH binding to the αvβ3 integrin was published, a comprehensive analysis of additional TH metabolites is lacking.…”

Image_5_P2Y6 and P2X7 Receptor Antagonism Exerts Neuroprotective/ Neuroregenerative Effects in an Animal Model of Parkinson’s Disease.TIF by Ágatha Oliveira-Giacomelli (7833929)

“…<p>Parkinson’s disease (PD) is a neurodegenerative disorder characterized by decreased dopamine bioavailability in the substantia nigra and the striatum. …”

Image5_Identification of Alternative Splicing-Related Genes CYB561 and FOLH1 in the Tumor-Immune Microenvironment for Endometrial Cancer Based on TCGA Data Analysis.JPEG by Dan Sun (140898)

Table_1_MiR-199b-5p Suppresses Tumor Angiogenesis Mediated by Vascular Endothelial Cells in Breast Cancer by Targeting ALK1.docx by Xiao Lin (20892)

“…Taken together, these findings demonstrate the anti-angiogenic role of miR-199b-5p, which directly targets ALK1, suggesting that miR-199b-5p might be a potential anti-angiogenic target for cancer therapy.…”

Image_1_Fecal microbiota transplantation confirmed that 919 Syrup reduced the ratio of erucamide to 5-AVAB in hippocampus to alleviate postpartum depression by regulating gut micro... by Qiaoqi Zheng (15861563)

“…However, mice treated with antibiotics were not sensitive to the anti-postnatal depression effect of 919 Syrup, and the level of 5-aminovaleric acid betaine (5-AVAB) in their hippocampus was significantly decreased. …”

Table 5_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... by Yuan Li (67017)

“…DALYs lost totaled 5,040,596 years (95% UI: 4,432,534–5,654,102), with a DALY rate of 249.334 (95% UI: 222.411–277.622) per 100,000 people. …”

DataSheet1_ER Stress–Related Genes EIF2AK3, HSPA5, and DDIT3 Polymorphisms are Associated With Risk of Lung Cancer.XLSX by Yongshi Liu (13112109)

“…</p><p>Methods: Six single-nucleotide polymorphisms (SNPs) of EIF2AK3, HSPA5, and DDIT3 were genotyped in 620 cases and 620 controls using a MassARRAY platform.…”

DataSheet1_Investigating the induction of polyphenol biosynthesis in the cultured Cycolocarya paliurus cells and the stimulatory mechanism of co-induction with 5-aminolevulinic aci... by Li-Juan Ling (568769)

“…Elicitation is regarded as one of the most effective ways to improve the output of the secondary metabolites, and therefore has attracted extensive attention.</p><p>Methods: Five elicitors including 5-aminolevulinic acid (5-ALA), salicylic acid (SA), methyl jasmonate (MeJA), sodium nitroprusside (SNP) and Rhizopus Oryzae Elicitor (ROE) were used to improve the content and yield of polyphenols in the cultured Cyclocarya paliurus (C. paliurus) cells, and a co-induction technology of 5-ALA and SA was developed as a result. …”

DataSheet2_ER Stress–Related Genes EIF2AK3, HSPA5, and DDIT3 Polymorphisms are Associated With Risk of Lung Cancer.XLSX by Yongshi Liu (13112109)

“…</p><p>Methods: Six single-nucleotide polymorphisms (SNPs) of EIF2AK3, HSPA5, and DDIT3 were genotyped in 620 cases and 620 controls using a MassARRAY platform.…”

Expression of FOXM1 promotes mucinous characteristics in mouse lung tumors induced either by urethane or Kras^G12D. by David Milewski (4710029)

“…<b>(B)</b> <i>Nkx2-1</i> mRNA was decreased in microdissected <i>epiFoxM1-ΔN</i> tumors (n = 5) compared to control tumors (n = 5) as shown by qRT-PCR. …”

Aggregation of Charge Acceptors on Nanocrystal Surfaces Alters Rates of Photoinduced Electron Transfer by Danielle M. Cadena (14198294)

“…As the concentration of PDI acceptors is increased, we find the average electron transfer rate from PbS to PDI ligands decreases by nearly an order of magnitude. …”

Table5_Rhizoma Gastrodiae Water Extract Modulates the Gut Microbiota and Pathological Changes of P-TauThr231 to Protect Against Cognitive Impairment in Mice.DOCX by Wenbin Zhao (4026677)

Image_5_MicroRNA-5112 Targets IKKγ to Dampen the Inflammatory Response and Improve Clinical Symptoms in Both Bacterial Infection and DSS-Induced Colitis.jpeg by Xilong Kang (2548195)

“…The overexpression of miR-5112 decreased inflammatory cytokine production, accompanied by a reduction of IKKγ in flagellin-stimulated BMDCs. …”

Image_5_circATP2B1 Promotes Aerobic Glycolysis in Gastric Cancer Cells Through Regulation of the miR-326 Gene Cluster.jpeg by Xihe Zhao (10651019)

“…Taken together, circATP2B1 captured miR-326-3p/miR-330-5p and decreased the suppression of PKM2 by miR-326-3p/miR-330-5p, thus aiding the aerobic glycolysis and proliferation of gastric cancer cells. …”

Image_5_circATP2B1 Promotes Aerobic Glycolysis in Gastric Cancer Cells Through Regulation of the miR-326 Gene Cluster.jpeg by Xihe Zhao (10651019)

“…Taken together, circATP2B1 captured miR-326-3p/miR-330-5p and decreased the suppression of PKM2 by miR-326-3p/miR-330-5p, thus aiding the aerobic glycolysis and proliferation of gastric cancer cells. …”

Systemic inflammation is decreased in <i>Sharpin^cpdm-Dem</i>, <i>Rag1^−/−</i> double mutant mice but significantly increased in <i>Sharpin^cpdm-Dem</... by Christopher S. Potter (356079)

Table_1_A Supramolecular Interaction of a Ruthenium Complex With Calf-Thymus DNA: A Ligand Binding Approach by NMR Spectroscopy.DOCX by Flávio Vinícius Crizóstomo Kock (7840328)

“…Besides, the STD-NMR titration experiments revealed a stronger interaction (K_D = 5.9 mM) for CBLAU-DNA in comparison to non-complexed lawsone-DNA (K_D = 34.0 mM). …”

DataSheet1_miR-21-5p/PRKCE axis implicated in immune infiltration and poor prognosis of kidney renal clear cell carcinoma.PDF by Jinxiang Wang (416744)

“…In summary, PRKCE may serve as a novel prognostic biomarker reflecting immune infiltration level and a novel therapeutic target in KIRC.…”