Effect of rapamycin (1 ng/ml) and anti-EGFR antibody (5 µg/ml) on reactivity with monoclonal HMB45 in human TSC2^−/−ASM cells. by Elena Lesma (269724)

“…<p>Positive cells are indicated as ++, slightly positive as + and negative as −. A: Incubation at cell plating time with anti-EGFR for 48 hours decreases markedly the number of cells reacting to HMB45 while the number of negative cells is strongly increased. …”

Unsupervised hierarchical cluster analysis of genes and experiments of nine normal genital skin fibroblast lines (penile foreskin) and five AIS genital skin fibroblast lines (labia... by Paul-Martin Holterhus (55368)

Nuclear phenotypes appear to be altered in HeLa cells in response to VPA treatment. by Giovana M. B. Veronezi (3691900)

Data_Sheet_1_Alternative Mating Tactics in Socially Monogamous Prairie Voles, Microtus ochrogaster.pdf by Stephen M. Shuster (629138)

“…We found that: (1) the average fitnesses of males and females within each population were identical when adjusted by the sex ratio; (2) the variance in fitness in male and female prairie voles was comparable to that of highly polygynous species; (3) The average fitnesses of male tactics, and of female tactics, were equivalent within and among years within each location; (4) consistent with negative frequency-dependent selection acting on mating phenotypes, the between-tactic variance in fitness for male and female mating tactics decreased with increasing study duration; (5) consistent with negative assortative mating, resident males, and wanderer females produced offspring primarily in monogamous partnerships, whereas wanderer males and resident females produced offspring primarily in polygamous partnerships. …”

Data_Sheet_4_Alternative Mating Tactics in Socially Monogamous Prairie Voles, Microtus ochrogaster.pdf by Stephen M. Shuster (629138)

“…We found that: (1) the average fitnesses of males and females within each population were identical when adjusted by the sex ratio; (2) the variance in fitness in male and female prairie voles was comparable to that of highly polygynous species; (3) The average fitnesses of male tactics, and of female tactics, were equivalent within and among years within each location; (4) consistent with negative frequency-dependent selection acting on mating phenotypes, the between-tactic variance in fitness for male and female mating tactics decreased with increasing study duration; (5) consistent with negative assortative mating, resident males, and wanderer females produced offspring primarily in monogamous partnerships, whereas wanderer males and resident females produced offspring primarily in polygamous partnerships. …”

Data_Sheet_3_Alternative Mating Tactics in Socially Monogamous Prairie Voles, Microtus ochrogaster.xlsx by Stephen M. Shuster (629138)

“…We found that: (1) the average fitnesses of males and females within each population were identical when adjusted by the sex ratio; (2) the variance in fitness in male and female prairie voles was comparable to that of highly polygynous species; (3) The average fitnesses of male tactics, and of female tactics, were equivalent within and among years within each location; (4) consistent with negative frequency-dependent selection acting on mating phenotypes, the between-tactic variance in fitness for male and female mating tactics decreased with increasing study duration; (5) consistent with negative assortative mating, resident males, and wanderer females produced offspring primarily in monogamous partnerships, whereas wanderer males and resident females produced offspring primarily in polygamous partnerships. …”

Fluorescent microscopy (OC1, ×40) and quantitative assay for hair cell damage in the five and six days post-fertilization (dpf) transgenic zebrafish (Brn3C: EGFP). by Jiwon Chang (845290)

“…Treatment with neomycin resulted in a significant decrease in the number of hair cells, but 500μM sodium selenite most attenuated the hair cell damage (A). …”

qRT-PCR analysis of the relative expression levels of TGF-β1, BMP-4 and Smads in embryonic bladders from E12.5 to neonatal day0. by Syed S. Islam (404861)

“…<b>A</b>) BMP-responsive R-Smads. Smad1, Smad5 and Smad8 were expressed in all gestation stages. …”

Impairments in recognition memory and mesohippocampal dopaminergic fibers induced in the mouse ventral hippocampus after chronic GBR12935 infusions. by Jill Rocchetti (16883936)

Image_5_Single-cell transcriptome in silico analysis reveals conserved regulatory programs in macrophages/monocytes of abdominal aortic aneurysm from multiple mouse models and huma... by Shiyong Wu (697200)

“…Mφ/Mo from human AAA dataset was divided into five subtypes. The proportion of three macrophage subpopulations increased but the proportion of two monocyte subpopulations decreased. …”

Impact of a drug dispensing model at a Community Pharmacy in Goiânia, Goiás, Brazil by Tatyana Xavier Almeida Matteucci Ferreira (6573785)

Image_5_Toxoplasma gondii Dense Granule Proteins 7, 14, and 15 Are Involved in Modification and Control of the Immune Response Mediated via NF-κB Pathway.TIF by Fumiaki Ihara (4592044)

“…We found that GRA7 and GRA14 were partially involved in the activation of NFκB, whereas GRA15 was essential for NFκB activation. …”

Image_2_SCD2-mediated cooperative activation of IRF3-IRF9 regulatory circuit controls type I interferon transcriptome in CD4+ T cells.tiff by Toshio Kanno (13266066)

“…<p>Type I interferons (type I-IFN) are critical for the host defense to viral infection, and at the same time, the dysregulation of type I-IFN responses leads to autoinflammation or autoimmunity. Recently, we reported that the decrease in monounsaturated fatty acid caused by the genetic deletion of Scd2 is essential for the activation of type I-IFN signaling in CD4⁺ Th1 cells. …”

Table 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.xls by Xue Li (285380)

“…In this study, we aimed to investigate the dose-dependent effects of co-DR1/2I (combined administration of dopamine receptor 1 inhibitor SCH39166 and dopamine receptor 2 inhibitor raclopride) on oxidative stress, learning, memory, emotion, and motor function in the substantia nigra, striatum, and hippocampus of mice.…”

Video_2_Severe Spinal Cord Injury in Rats Induces Chronic Changes in the Spinal Cord and Cerebral Cortex Metabolism, Adjusted by Thiamine That Improves Locomotor Performance.MP4 by Alexandra Boyko (10489220)

“…The biochemical and physiological assessments 8 weeks after SCI reveal that thiamine, but not TEGP, alleviates the SCI-induced perturbations in the rat brain metabolism, accompanied by the decreased expression of (acetyl)p53, increased expression of sirtuin 5 and an 18% improvement in the locomotor recovery. …”

Data_Sheet_1_Severe Spinal Cord Injury in Rats Induces Chronic Changes in the Spinal Cord and Cerebral Cortex Metabolism, Adjusted by Thiamine That Improves Locomotor Performance.d... by Alexandra Boyko (10489220)

“…The biochemical and physiological assessments 8 weeks after SCI reveal that thiamine, but not TEGP, alleviates the SCI-induced perturbations in the rat brain metabolism, accompanied by the decreased expression of (acetyl)p53, increased expression of sirtuin 5 and an 18% improvement in the locomotor recovery. …”

Video_1_Severe Spinal Cord Injury in Rats Induces Chronic Changes in the Spinal Cord and Cerebral Cortex Metabolism, Adjusted by Thiamine That Improves Locomotor Performance.MP4 by Alexandra Boyko (10489220)

“…The biochemical and physiological assessments 8 weeks after SCI reveal that thiamine, but not TEGP, alleviates the SCI-induced perturbations in the rat brain metabolism, accompanied by the decreased expression of (acetyl)p53, increased expression of sirtuin 5 and an 18% improvement in the locomotor recovery. …”

Data_Sheet_2_Dysbiosis of the Gut Microbiome in Lung Cancer.PDF by He Zhuang (6332147)

Data_Sheet_2_Dysbiosis of the Gut Microbiome in Lung Cancer.PDF by He Zhuang (6332147)

Heatmap and hierarchical clustering of clinical and hematological data across the 23 cattle utilized for transcriptome network analysis. by Matthew A. Scott (3915533)

“…Colors indicate an increase (yellow/white) or decreased (purple/black) value for each trait; Sex and BRD are both represented as a value of 1 for bulls and Yes, and 0 for steers and No, respectively.…”