Discovery of Novel Imidazo[4,5‑<i>c</i>]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Inte... by Xuewu Liang (3071676)

“…In the current study, we discovered a series of imidazo[4,5-<i>c</i>]quinoline derivatives that potently and simultaneously inhibited two primary proinflammatory signaling pathways JAK/STAT and NF-κB. …”

Transmural cable simulations. by Aditya V. S. Ponnaluri (3164673)

DataSheet_1_Coelomocyte populations in the sea urchin, Strongylocentrotus purpuratus, undergo dynamic changes in response to immune challenge.pdf by Megan A. Barela Hudgell (11701967)

“…Responses to zymosan A show decreases in the concentration of large phagocytes and increases in the concentration of small phagocytes. …”

Delta APD maps generated by computing the difference between the APDs of two subsequent beats measured in milliseconds. by Aditya V. S. Ponnaluri (3164673)

Effect of a spray formulation on the reproductive parameters of a susceptible population of Rhipicephalus (Boophilus) microplus by Breno Cayeiro Cruz (5311052)

“…The engorged female weight (days 1 to 7), weight of egg masses (days 5 to 10) and larval hatching percentage (days 5 to 19) were decreased (P ≤ 0.05). …”

SFN Inhibited invasion via sustained activation of ERK1/2. by Chunliu Li (284115)

“…Data were shown as means ± SD from three separate tests. (B) We seeded 1×10⁵ cells in a 24-well plate with cell inserts, the cells were added with SFN (20 µM) without or with PD98059 (25 µM) for 24 h to detect cell invasion. …”

Prediction of transition readiness. by Sharon Barak (4803966)

“…Forty-two people with DMD or BMD (mean age: 24.3±5.3) participated in this study. The transition domains in which most participants needed help were education and employment (52.5%) and activities of daily living (57.0%). …”

Extended visualization of MitoTNT tracking in hiPSC. by Zichen Wang (2473054)

An Example to Illustrate the Issue of Potential False Negatives of MC and CO. by Wei Zhuang (146641)

Lipocalin 2 Enhances Migration and Resistance against Cisplatin in Endometrial Carcinoma Cells by Tsutomu Miyamoto (2742265)

“…We previously identified LCN2 as an up-regulated gene in endometrial carcinoma, and found that the overexpression of LCN2 and its receptor, SLC22A17, was associated with a poor prognosis. …”

Cholesterol replenishment inhibits antiviral effect of amiodarone. by Szilvia Barsi (12400967)

Improving Cu₂ZnSnS₄‑Based Photocathodes for Solar Water Splitting via SnO₂ Overlayers by Peng Guo (134478)

“…Herein, we use SnO₂ to modify the CdS/Cu₂ZnSnS₄ photocathode by a straightforward spin-coating process, significantly improving the photoelectrode efficiency and stability. …”

Improving Cu₂ZnSnS₄‑Based Photocathodes for Solar Water Splitting via SnO₂ Overlayers by Peng Guo (134478)

“…Herein, we use SnO₂ to modify the CdS/Cu₂ZnSnS₄ photocathode by a straightforward spin-coating process, significantly improving the photoelectrode efficiency and stability. …”

Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes by Charles Thivolet (4275982)

“…The role of the endoplasmic reticulum–mitochondria junction in coordinating the functions of these two organelles throughout the natural history of type 2 diabetes is determinant and may explain the alterations of insulin biosynthesis. …”

Diet Modification and Metformin Have a Beneficial Effect in a Fly Model of Obesity and Mucormycosis by Fazal Shirazi (413427)

“…<div><p>In an experimental model of obesity and hyperglycemia in <i>Drosophila melanogaster</i> we studied the effect of diet modification and administration of metformin on systemic infection with <i>Rhizopus</i>, a common cause of mucormycosis in diabetic patients. …”

Data_Sheet_1_Arabidopsis FHY3 and FAR1 Function in Age Gating of Leaf Senescence.pdf by Yurong Xie (11616862)

“…However, how they coordinately regulate leaf senescence during leaf development remains largely unclear. In this study, we show that FHY3 and FAR1, two homologous proteins essential for phytochrome A-mediated light signaling, physically interact with and repress the DNA binding activity of EIN3 (a key transcription factor essential for ethylene signaling) and PIF5 (a bHLH transcription factor negatively regulating light signaling), and interfere with their DNA binding to the promoter of ORE1, which encodes a key NAC transcription factor promoting leaf senescence. …”

Fabrication of Recyclable Polyisoprene Elastomers with Tuneable Mechanical Properties by Incorporating Dynamic Bonds and Separated Polystyrene Phase by Meijuan Xie (8427819)

“…The experimental results show that the flow of PS phases above <i>T</i>_g,PS effectively accelerates the rearrangement of dynamic covalent networks, so that the exchange activation energy (<i>E</i>_a) and topological freezing transition temperature (<i>T</i>_v) of the samples decrease with the increase of the PS phase content, giving the samples superior recyclability and self-healing ability. …”

Creating an amplifier of weak selection for death-Birth updating. by Benjamin Allen (408337)

“…We solve for remeeting times according to Eqs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007529#pcbi.1007529.e014" target="_blank">(5)</a> and <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007529#pcbi.1007529.e015" target="_blank">(6)</a>, and identify the vertex with the largest remeeting time (<i>τ</i>_<i>i</i> ≈ 18.29, shown in magenta). …”

Data_Sheet_1_CK5/6 and GATA3 Defined Phenotypes of Muscle-Invasive Bladder Cancer: Impact in Adjuvant Chemotherapy and Molecular Subtyping of Negative Cases.pdf by Florestan J. Koll (11753237)

“…In the multivariate Cox-regression model, patients receiving adjuvant chemotherapy had a significant survival benefit (hazard ratio [HR]: 0.19 95% confidence interval [CI]: 0.1–0.4, p < 0.001) and double-negative cases had decreased OS (HR: 4.07; 95% CI: 1.5–10.9, p = 0.005). …”

Table_2_The effects of pemafibrate and omega-3 fatty acid ethyl on apoB-48 in dyslipidemic patients treated with statin: A prospective, multicenter, open-label, randomized, paralle... by Yasutaka Takeda (3165264)

“…Background<p>We compared the lowering effects of pemafibrate and omega-3 fatty acid ethyl on fasting apolipoprotein (apo) B-48 (apoB-48), a marker that reflects postprandial hypertriglyceridemia, which is one of the residual risks for atherosclerotic cardiovascular disease (ASCVD) with statin treatment.…”