Image3.JPEG by Swetlana Gautam (5069798)

“…<p>The present study is a pursuit to define implications of dual cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) (DuCLOX-2/5) inhibition on various aspects of cancer augmentation and chemoprevention. …”

Image6.JPEG by Swetlana Gautam (5069798)

“…<p>The present study is a pursuit to define implications of dual cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) (DuCLOX-2/5) inhibition on various aspects of cancer augmentation and chemoprevention. …”

Main karyotypic groups/types distinguished among <i>T</i>. <i>dicoccon</i> accessions on the basis of visual analysis of C-banding patterns. by Ekaterina D. Badaeva (746941)

“…Large black arrows show the breakpoint position in region-specific translocation variants: T7AS.7AL-5BS and T5BL.5BS-7AL—rearranged chromosomes formed as a result of the T7A:5B translocation; T4AS:1BL and T1BS:4AL—rearranged chromosomes formed as a result of the T4A:1B translocation; T1AS.1AL-6AS and T6AL.6AS-1AL—rearranged chromosomes formed as a result of the T1A:6A translocation; T4BS:6BL and T6BS:4BL—rearranged chromosomes formed as a result of the T4B:6B-1 translocation (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0128556#pone.0128556.s016" target="_blank">S3</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0128556#pone.0128556.s017" target="_blank">S4</a> Tables).…”

The result of a density multiplying simulation. by Atsushi Honma (246212)

“…<p>The densities of the Mimic and the Model vary between 0 and 0.5 while their ratio remains constant (1∶1). Each point and error bar represent the mean and standard deviation of the replications. …”

Macrophage-Derived Angiopoietin-Like Protein 2 Exacerbates Brain Damage by Accelerating Acute Inflammation after Ischemia-Reperfusion by Toshihiro Amadatsu (3352955)

“…Both neurological deficits and infarct volume decreased in transient MCAO model mice established in <i>Angptl2</i> knockout (KO) relative to wild-type mice. …”

Data Sheet 1_Sodium-glucose cotransporter 2 inhibitors—but not insulin—enhance renal branched-chain amino acid catabolism.docx by Moeko Sakamoto (22578098)

“…</p>Methods<p>We conducted a prospective, single-center, open-label, nonrandomized, controlled clinical study in patients with type 2 diabetes stably treated with insulin, who were assigned to dapagliflozin (5 mg/day with dose-reduced insulin; n=8/9 completed) or insulin dose-up (n=5/8 completed). …”

Supplementary Material for: Novel Cranial Imaging Findings and a Splice-Site Variant in a Patient with Tyrosinemia Type III, and a Summary of Published Cases by Kahraman A.B. (11900960)

Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization by Stefania Butini (1714288)

“…The most promising compounds ((±)-<b>5c</b>, (±)-<b>5d</b>, and (±)-<b>5v</b>) were used for <i>in vivo</i> studies in mice, showing a decrease in MAGL activity and increased 2-arachidonoyl-<i>sn</i>-glycerol levels in forebrain tissue. …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

Real-time NO release profiles of the HPMC/GSNO formulations. by Maria Adriana Skeff (670466)

Epoxygenase <i>Cyp2c44 </i>regulates hepatic lipid metabolism and insulin signaling by controlling FATP2 localization and activation of the DAG/PKCδ axis by Kakali Ghoshal (4639600)

“…We showed increased hepatic plasma membrane localization of the FA transporter 2 (FATP2) and total unsaturated fatty acids and diacylglycerol levels. …”

Rottlerin reverses PRRSV-induced activation of cofilin and LIMK1. by Yeonglim Kang (21395261)

A New Approach to Improving Healthcare Personnel Influenza Immunization Programs: A Randomized Controlled Trial by Larry W. Chambers (704112)

“…No significant differences were observed between the groups at the three points in time. However, there was a 7% increase in the median rates between the Baseline Year and Year Two in the Intervention group, and a 6% decrease in the Control group over the same time period, which was statistically significant (0.071 versus -0.058, p < 0.001).…”

Identification of regions of interest to perform ligations between blood vessels. by Pablo Castro-Córdova (5614352)

A Customized Pigmentation SNP Array Identifies a Novel SNP Associated with Melanoma Predisposition in the <em>SLC45A2</em> Gene by Maider Ibarrola-Villava (223306)

“…In this study, 363 SNPs in 65 gene regions belonging to the pigmentation pathway have been successfully genotyped using a SNP array. Five hundred and ninety MM cases and 507 controls were analyzed in a discovery phase I. …”

Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets by Fardoun, Manal Muin

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Fidgetin-Like1 Is a Strong Candidate for a Dynamic Impairment of Male Meiosis Leading to Reduced Testis Weight in Mice by David L'Hôte (197958)

“…<div><h3>Background</h3><p>In a previous work, using an interspecific recombinant congenic mouse model, we reported a genomic region of 23 Mb on mouse chromosome 11 implicated in testis weight decrease and moderate teratozoospermia (∼20–30%), a Quantitative Trait Locus (QTL) called Ltw1. …”

Blocking IL-17A reduces pulmonary expression of <i>Arg1 and Clec10a</i>. by Joel A. Mathews (563208)

“…Note that an increase in Ct indicates a decrease in expression. Mice were exposed to O₃ for either 48 or 72 h and euthanized immediately after cessation of exposure. …”

Image_2_Consortium of Probiotics Attenuates Colonization of Clostridioides difficile.JPEG by Xianping Li (3327297)

“…In our study, we evaluated the effect of consortium of probiotics including five Lactobacilli strains and two Bifidobacterium strains on the colonization of toxigenic BI/NAP1/027 C. difficile in a mouse model. …”

Table_2_Consortium of Probiotics Attenuates Colonization of Clostridioides difficile.XLSX by Xianping Li (3327297)

“…In our study, we evaluated the effect of consortium of probiotics including five Lactobacilli strains and two Bifidobacterium strains on the colonization of toxigenic BI/NAP1/027 C. difficile in a mouse model. …”