Hematopoietic Protein-1 Regulates the Actin Membrane Skeleton and Membrane Stability in Murine Erythrocytes by Maia M. Chan (281339)

“…Increased adducin Ser724 phosphorylation in <em>Hem1^−/−</em> erythrocytes correlates with decreased protein expression of the regulatory subunit of protein phosphatase 2A (PP2A), which is required for PP2A-dependent dephosphorylation of PKC targets. …”

Stereoselective Palladium-Catalyzed Base-Free Suzuki–Miyaura Cross-Coupling of Tetrasubstituted <i>gem</i>-Difluoroalkenes: An Experimental and Computational Study by Yanhui Wang (108090)

“…Density functional theory (DFT) calculations elucidated an intriguing reaction pathway favoring a formal [4 + 1] cycloaddition of Pd(0), followed by 1,5-sigmatropic fluoride migration, assisted by the chelation of the ester-substituent group to Pd center. …”

MicroRNA Expression Profiling Identifies Activated B Cell Status in Chronic Lymphocytic Leukemia Cells by Shuqiang Li (228142)

“…Additionally, decreased levels of two CLL signature miRNAs miR-29c and miR-223 are associated with ZAP70⁺ and IgV_H unmutated status and with shorter time to first therapy. …”

Stereoselective Palladium-Catalyzed Base-Free Suzuki–Miyaura Cross-Coupling of Tetrasubstituted <i>gem</i>-Difluoroalkenes: An Experimental and Computational Study by Yanhui Wang (108090)

“…Density functional theory (DFT) calculations elucidated an intriguing reaction pathway favoring a formal [4 + 1] cycloaddition of Pd(0), followed by 1,5-sigmatropic fluoride migration, assisted by the chelation of the ester-substituent group to Pd center. …”

Supplementary Material for: Retrospective Study of Transjugular Intrahepatic Portosystemic Shunt Placement for Cirrhotic Portal Hypertension by Santos S. (8951453)

“…TIPS-related adverse events occurred in 29/51 (56.8%) patients, with hepatic encephalopathy (HE) in 21 (41%) patients, sepsis in 3, liver failure in 2, hemolytic anemia in 1, acute pulmonary edema in 1, and capsular perforation in 1 patient. Mean follow-up was 15.7 ± 15 months. First-month mortality was 11.7% (<i>n</i> = 6) (sepsis, <i>n</i> = 3; acute liver failure, <i>n</i> = 2; and recurrence of variceal bleeding, <i>n</i> = 1) and was significantly higher for patients with Child-Pugh >9 points (<i>p</i> = 0.01), model of end-stage liver disease (MELD) scores >19 (<i>p</i> = 0.02), and for patients with a history of HE before the procedure (<i>p</i> = 0.001). …”

MDT-15 limits the growth and longevity at low temperatures. by Dongyeop Lee (108880)

“…(<i>n</i> ≥ 248 from five independent experiments.) We were able to maintain <i>mdt-15(-)</i> worms at low temperatures because the embryonic lethality was not 100%. …”

The expression of cell cycle and apoptosis regulators in induced and tolerant iDCs at 27h. by Kata Filkor (455814)

“…<p>Based on the SAGE-Seq data, we have chosen 2 cell cycle regulators, cyclin B2 (A) and cyclin D1 (B), and three apoptosis regulators, caspase-8 (C), FADD (D) and TGF-β (E) for the validation by QRT-PCR. …”

Altered Expression of Polycomb Group Genes in Glioblastoma Multiforme by Gang Li (34549)

“…We validated the aberrant expression of CBX6, CBX7, CBX8 and EZH2 in GBM cell lines by Western blotting and qRT-PCR, and further the aberrant expression of CBX6 in GBM tissue samples by immunohistochemical staining. …”

Image1_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.TIF by Zhengxin Ma (6309152)

“…We found that, while GCN2 phosphorylates eIF2α when nutrients are restricted, the ability to phosphorylate eIF2α is not required for changes in translation, nonsense-mediated decay, or lifespan associated with dietary restriction (DR). …”

DataSheet1_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.doc... by Zhengxin Ma (6309152)

“…We found that, while GCN2 phosphorylates eIF2α when nutrients are restricted, the ability to phosphorylate eIF2α is not required for changes in translation, nonsense-mediated decay, or lifespan associated with dietary restriction (DR). …”

Image4_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.TIF by Zhengxin Ma (6309152)

“…We found that, while GCN2 phosphorylates eIF2α when nutrients are restricted, the ability to phosphorylate eIF2α is not required for changes in translation, nonsense-mediated decay, or lifespan associated with dietary restriction (DR). …”

Image6_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.TIF by Zhengxin Ma (6309152)

“…We found that, while GCN2 phosphorylates eIF2α when nutrients are restricted, the ability to phosphorylate eIF2α is not required for changes in translation, nonsense-mediated decay, or lifespan associated with dietary restriction (DR). …”

Image3_The integrated stress response protects against ER stress but is not required for altered translation and lifespan from dietary restriction in Caenorhabditis elegans.TIF by Zhengxin Ma (6309152)

“…We found that, while GCN2 phosphorylates eIF2α when nutrients are restricted, the ability to phosphorylate eIF2α is not required for changes in translation, nonsense-mediated decay, or lifespan associated with dietary restriction (DR). …”

PolyQ expansion affects p53-dependent apoptotic function in cells and in zebrafish. by Hongmei Liu (129385)

“…<p>(A) HCT116 p53^+/+ and HCT116 p53^-/- cells transiently transfected with Flag-vector or normal Flag-ATX-3 or Flag-ATX-3-80Q were treated with CPT (1 μM) for 24 h and then analyzed by flow cytometry for apoptosis using Annexin-V/PI. …”

MUS81 causes DNA double-strand breaks upon Chk1 inhibition that result in cell death. by Josep V. Forment (119177)

“…Cells were transfected as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023517#pone-0023517-g002" target="_blank">Fig. 2</a>, and left untreated (NT) or treated with 50 nM AZD7762 (AZD), 2.5 µM aphidicolin (Aph), or a combination of both drugs (A+A) for 12 h. …”

Table_1_Racialized Pandemic: The Effect of Racial Attitudes on COVID-19 Conspiracy Theory Beliefs.DOCX by Christina E. Farhart (12267698)

“…<p>As national and international health agencies rushed to respond to the global spread of a novel coronavirus (SARS-CoV-2, commonly known as COVID-19), one challenge these organizations faced was the spread of misinformation and conspiracy theories about the virus. …”

Data_Sheet_1_Racialized Pandemic: The Effect of Racial Attitudes on COVID-19 Conspiracy Theory Beliefs.ZIP by Christina E. Farhart (12267698)

“…<p>As national and international health agencies rushed to respond to the global spread of a novel coronavirus (SARS-CoV-2, commonly known as COVID-19), one challenge these organizations faced was the spread of misinformation and conspiracy theories about the virus. …”

Modeling Retinal Degeneration Using Patient-Specific Induced Pluripotent Stem Cells by Zi-Bing Jin (230558)

“…It is well known that the disease is caused by rod photoreceptor degeneration; however, it remains incurable, due to the unavailability of disease-specific human photoreceptor cells for use in mechanistic studies and drug screening. We obtained fibroblast cells from five RP patients with distinct mutations in the <em>RP1</em>, <em>RP9</em>, <em>PRPH2</em> or <em>RHO</em> gene, and generated patient-specific induced pluripotent stem (iPS) cells by ectopic expression of four key reprogramming factors. …”

Evaluation of functional changes of the retina by electroretinography (ERG). by Po-Ting Yeh (845796)

“…<p>The ERG were performed on untreated rats (Control) or STZ-induced diabetic rats treated for 8 weeks with normal saline (Diabetes), 3 mg/kg AST (AST High), 0.6 mg/kg AST (AST Low), or 0.5 mg/kg lutein (Lutein). The relative b-wave ratio was significantly decreased in the Diabetes, AST Low and Lutein groups compared with the Control group. …”

Supplementary Material for: Exploring associations between cannabis prices, stores, and usage after recreational legalization by figshare admin karger (2628495)

“…Edibles use increased and was negatively associated with prices. Mean initial age of use increased; it was negatively associated with prices and positively with stores. …”