Overexpression of mutant ATXN2 in human SH-SY5Y cells recapitulates down-regulation of <i>in vivo</i> steady-state levels of Rgs8 in BAC-Q72 mice. by Warunee Dansithong (119577)

“…<b>(B)</b> Quantitative RT-PCR analyses of synthesized cDNAs from the other aliquot demonstrate moderate reduction of <i>RGS8</i> mRNA in cells expressing Flag-ATXN2-Q108. The data are means ± SD, *p<0.05. <b>(C)</b> Mutant ATXN2 specifically induces decrease of RGS8 expression. …”

H& E staining investigation of CAM treated with native-orientin (5 μM), native-orientin (10 μM), NF-O (5 μM), and NF-O (10 μM). by Yashwanth Elumalai (21743452)

Disruption of <i>shk-1</i> increases susceptibility to bacterial pathogens. by Longjun Pu (20685717)

Measurement of the MMP in HL-1 cells exposed for 12 or 72h to LG, NG, HG or IHG. by Patrick Mordel (17020879)

Loss of Anticodon Wobble Uridine Modifications Affects tRNA^Lys Function and Protein Levels in <i>Saccharomyces cerevisiae</i> by Roland Klassen (699777)

“…However, an <i>elp3</i> disruption strain displays synthetic sick interaction and synergistic temperature sensitivity when combined with either <i>uba4</i> or <i>urm1</i> mutations, suggesting major translational defects in the absence of mcm⁵s²U modifications. Consistent with this notion, we find cellular protein levels drastically decreased in an <i>elp3uba4</i> double mutant and show that this effect as well as growth phenotypes can be partially rescued by excess of tRNA^Lys_UUU. …”

DataSheet5_Alterations of the Ca2+ clearing mechanisms by type 2 diabetes in aortic smooth muscle cells of Zucker diabetic fatty rat.PDF by Adriana Moreno-Salgado (15458003)

“…In addition, we found an increase in Ca²⁺ entry through the reverse mode of NCX and a decrease in SERCA and PMCA activity during the late stage of the signal decay. …”

Evaluation of glucose consumption and lactate production in culture medium of HL-1 cells exposed to LG, NG, HG and IHG during 12 and 72h. by Patrick Mordel (17020879)

JAK2, SRC, and EGFR promote Ras phosphorylation at Y4. by Chalita Washington (8997378)

“…Therefore, we titrated the amount of JAK2 in kinases assays and could reliably see a response using 20 micrograms of kinase used in subsequent assays. …”

Self-reported change in diet, physical activity and medication taking compared to pre-COVID-19 in relation to trajectories of HbA1c in people with diabetes (N = 4,925). by Martin Gillies Banke Rasmussen (10227291)

Image_2_Distinct Brain Dynamic Functional Connectivity Patterns in Schizophrenia Patients With and Without Auditory Verbal Hallucinations.JPEG by Yao Zhang (134381)

“…In this study, 25 Schizophrenia patients with AVHs (AVHs group, 23.2 ± 5.35 years), 52 Schizophrenia patients without AVHs (non-AVHs group, 25.79 ± 5.63 years) and 28 healthy subjects (NC group, 26.14 ± 5.45 years) were enrolled. …”

Image_1_Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A.TIF by Brady Trevisan (10211405)

“…We found that flow conditions led to a significant increase in KLF2, which induces miRNAs that negatively regulate expression of FVIII and vWF, providing a mechanistic explanation for the reduced expression of these proteins in PLC under conditions of flow. …”

Table_1_Effects of Shear Stress on Production of FVIII and vWF in a Cell-Based Therapeutic for Hemophilia A.DOCX by Brady Trevisan (10211405)

“…We found that flow conditions led to a significant increase in KLF2, which induces miRNAs that negatively regulate expression of FVIII and vWF, providing a mechanistic explanation for the reduced expression of these proteins in PLC under conditions of flow. …”

PDRN upregulates SIRT1 protein expression in HaCaT cells exposed to UVB or H₂O₂. by Jingjing Chen (293564)

Comparison of the MMP in HL-1 cells exposed to LG, NG, HG and IHG between short- (12h) and long-time (72h) glucose treatment. by Patrick Mordel (17020879)

Complete blood count (CBC) values of dog samples. by Chanon Fa-ngoen (18121319)

“…No significant difference in seroprevalence for the three serogroups was observed in any of the 64 districts sampled. The mean hematocrit level significantly decreased in seropositive dogs (P<0.05). …”

Complete blood count (CBC) values of cat samples. by Chanon Fa-ngoen (18121319)

“…No significant difference in seroprevalence for the three serogroups was observed in any of the 64 districts sampled. The mean hematocrit level significantly decreased in seropositive dogs (P<0.05). …”

Relationship between age-dependent changes to transitions probabilities and gap durations within branch points. by Andrew M. M. Matheson (835763)

“…The magnitude of change (percent change) in gap durations varied depending on whether the prevalence of a transition within a branch point significantly decreased, did not significantly change, or significantly increased (Likelihood ratio test) over time. …”

Dataset for: Regional Septal Hinge-Point Injury Contributes to Adverse Biventricular Interactions in Pulmonary Hypertension by Eva Amalie Nielsen (845872)

“…Background: Death and morbidity in pulmonary arterial hypertension (PAH) are often due to right ventricular (RV) failure and associated left ventricular (LV) dysfunction. We investigated regional myocardial remodeling and function as the basis for adverse ventricular-ventricular interactions in experimental chronic RV pressure overload. …”

Secretion of IL-6 and IL-8 in Caco-2 cells treated with cytokines and α-MSH. by Judit Váradi (507449)

Video_5_Intradermal Injection of Oxytocin Aggravates Chloroquine-Induced Itch Responses via Activating the Vasopressin-1a Receptor/Nitric Oxide Pathway in Mice.mp4 by Rulong Li (1891597)

“…Notably, conivaptan also directly decreased CQ-induced scratching. In conclusion, OT plays a role in CQ-induced scratching behavior via V1AR binding events. …”