Comparison of glucose consumption and lactate production in culture medium of HL-1 cells exposed to LG, NG, HG and IHG between short- (12h) and long-time (72h) glucose treatment. by Patrick Mordel (17020879)

Ultralow Lattice Thermal Conductivity in the Aikinite Structure Family, Cu_<i>x</i>Pb_<i>x</i>Bi_2–<i>x</i>S₃, and Thermoelectric Propertie... by Srikanth Balijapelly (8974346)

“…In this article, we report the synthesis, characterization, and ultralow thermal conductivity of three complex quaternary chalcogenide compounds, Cu_<i>x</i>Pb_<i>x</i>Bi_2–<i>x</i>S₃ [<i>x</i> = 0.14(<b>I</b>), 0.33(<b>II</b>), and 1.0(<b>III</b>)], in the bismuthinite (Bi₂S₃)–aikinite (CuPbBiS₃) solid solution series. …”

Source data of Fig 2. by Wen Wen (596162)

“…<div><p>Maintaining and removing information in mind are 2 fundamental cognitive processes that decline sharply with age. …”

Htt-exon1(46Q) fibrils seed aggregation in a <i>C</i>. <i>elegans</i> strain (EAK102) expressing a non-pathogenic N-terminal htt fragment [htt-513(Q15)]. by Adam Skeens (18156026)

Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients by Baoqing Sun (558067)

“…Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. We investigated IgM and IgG responses against SARS-CoV-2 nucleocapsid (N) and spike (S) protein after symptom onset in the intensive care unit (ICU) and non-ICU patients. 130 blood samples from 38 COVID-19 patients were collected. …”

Table 2_MiR-99a-5p up-regulates LDLR and functionally enhances LDL-C uptake via suppressing PCSK9 expression in human hepatocytes.docx by Xuemei Chen (14465)

“…Conversely, anti-miR-99a-5p upregulates PCSK9, leading to a reduction in LDLR, attenuation of LDL-C uptake, and a decrease in the intracellular cholesterol levels of human hepatocytes. …”

PKC mediates apoA-I inhibition of endothelial exocytosis. by Scott J. Cameron (838315)

Membrane permeability of niosomes and liposomes. by Rianne Bartelds (1343631)

“…At time point 0 (indicated by an arrow), the medium pH was decreased from 7.5 to 6.3 by the addition of 10 mM HCl (large pulse) or from 7.5 to 7.0 by the addition of 4 mM HCl (small pulse). …”

Image_1_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

Image_3_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…Real-time PCR, dual-luciferase assay, and western blotting were employed to detect the relationship between miR-20a-5p and CD36. The expression level of miR-20a-5p was decreased in NAFLD patients, HFD mice, and free fatty acid (FFA)-treated HepG2 cells or primary mouse hepatocytes, accompanied by increased lipid production in hepatocytes. …”

image_1_P2Y2R Signaling Is Involved in the Onset of Glomerulonephritis.tif by Laura Rennert (5516531)

“…However, the involvement of purinergic receptors in glomerulonephritis (GN) has only been incompletely mapped. Here, we demonstrate that induction of GN in an experimental antibody-mediated GN model results in a significant increase of urinary ATP-levels and an upregulation of P2Y2R expression in resident kidney cells as well as infiltrating leukocytes pointing toward a possible role of the ATP/P2Y2R-axis in glomerular disease initiation. …”

Averaged first slice of second-order kernel of the mfERGs of the nasal hemisphere within the central 7.5° for different stages of glaucoma (Blue trace: Advanced stage, Brown trace:... by Naoya Moroto (14419705)

Atg14 deficiency in Tregs induces a type-I-dominant lymphoproliferative disease and cell-intrinsic reductions in eTregs. by Erienne G. Norton (9612079)

At 20-30 hpf, zebrafish heart is morphologically a tube-like structure with a AV canal (AV) separating the atrium (A) and ventricle (V). by Juhyun Lee (449913)

“…(b) Diastasis between atrial and ventricular contraction result in a decrease in shear stress across the AV canal. …”

Image_5_Severe COVID-19 Is Associated With an Altered Upper Respiratory Tract Microbiome.jpeg by Meghan H. Shilts (5900660)

“…</p>Objective<p>Our primary objective was to identify URT microbiome signature/s that consistently changed over a spectrum of COVID-19 severity.</p>Methods<p>Using data from 103 adult participants from two cities in the United States, we compared the bacterial load and the URT microbiome between five groups: 20 asymptomatic SARS-CoV-2-negative participants, 27 participants with mild COVID-19, 28 participants with moderate COVID-19, 15 hospitalized patients with severe COVID-19, and 13 hospitalized patients in the ICU with very severe COVID-19.…”

Cell viability as measured by MTT absorbance (abs) at 570nm, LDH release and intracellular NAD levels of microglial cells after 48 hour incubation in pooled, non heat inactivated a... by Tharusha Jayasena (704509)

Table5_Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac CaV1.2 calcium chan... by Liam Hovey (14584742)

“…<p>The cardiac calcium channel Ca_V1.2 conducts L-type calcium currents that initiate excitation-contraction coupling and serves as a crucial mediator of β-adrenergic regulation of the heart. …”

Image4_Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells.tif by Miguel Marco-Bonilla (16970271)

“…The expression of muscle differentiation proteins (Pax7, Mif5, MyoD, MyoG, and MHC), PKA/CREB, adenosine receptors (A1, A2A, A2B, and A3), ATP-channel pannexin-1 and the P2X7 receptor was analyzed via WB and RT-PCR. cAMP and AMPK activation was measured.…”

Image3_Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells.tif by Miguel Marco-Bonilla (16970271)

“…The expression of muscle differentiation proteins (Pax7, Mif5, MyoD, MyoG, and MHC), PKA/CREB, adenosine receptors (A1, A2A, A2B, and A3), ATP-channel pannexin-1 and the P2X7 receptor was analyzed via WB and RT-PCR. cAMP and AMPK activation was measured.…”

Image1_Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells.tif by Miguel Marco-Bonilla (16970271)

“…The expression of muscle differentiation proteins (Pax7, Mif5, MyoD, MyoG, and MHC), PKA/CREB, adenosine receptors (A1, A2A, A2B, and A3), ATP-channel pannexin-1 and the P2X7 receptor was analyzed via WB and RT-PCR. cAMP and AMPK activation was measured.…”