Inhibiting Gamma-secretase activity without interfering in Notch signaling: Decreasing the inflammatory response in patients with cutaneous leishmaniasis by Lucas Carvalho (3093042)

“…Statistical analyses were performed using the Wilcoxon test *P<0.05 and **P<0.01.</p><p><b>Figure 5 - Selective gamma-secretase inhibitor (JLK6) decreases pro-inflammatory cytokine production from CL patients.…”

Does the presence of exotic species decrease the initial development of native species in Brazilian seasonally dry tropical forests? by Carlos Leandro Costa Silva (12741450)

(a) Schematic of the sample preparation, (b) developed GFRPs samples modified, (c) samples for impact strength tests, (d) samples for compressive strength tests. by Shaban Gul (14309526)

Decreasing Abundance, Increasing Diversity and Changing Structure of the Wild Bee Community (Hymenoptera: Anthophila) along an Urbanization Gradient by Laura Fortel (614514)

“…We assessed changes in the abundance, species richness, and composition of wild bee community along an urbanization gradient.…”

T and B cells are markedly decreased in the VAT of CD11c-MyD88 KO DIO mice. by Manikandan Subramanian (789856)

Data_Sheet_1_The Effect of Allicin on the Proteome of SARS-CoV-2 Infected Calu-3 Cells.XLSX by Kirstin Mösbauer (5782847)

“…SARS-CoV-2 infection of Calu-3 cells caused a strong induction of the antiviral interferon-stimulated gene (ISG) signature, including several antiviral effectors, such as cGAS, Mx1, IFIT, IFIH, IFI16, IFI44, OAS, and ISG15, pathways of vesicular transport, tight junctions (KIF5A/B/C, OSBPL2, CLTCL1, and ARHGAP17) and ubiquitin modification (UBE2L3/5), as well as reprogramming of host metabolism, transcription and translation. …”

Data_Sheet_3_The Effect of Allicin on the Proteome of SARS-CoV-2 Infected Calu-3 Cells.XLSX by Kirstin Mösbauer (5782847)

“…SARS-CoV-2 infection of Calu-3 cells caused a strong induction of the antiviral interferon-stimulated gene (ISG) signature, including several antiviral effectors, such as cGAS, Mx1, IFIT, IFIH, IFI16, IFI44, OAS, and ISG15, pathways of vesicular transport, tight junctions (KIF5A/B/C, OSBPL2, CLTCL1, and ARHGAP17) and ubiquitin modification (UBE2L3/5), as well as reprogramming of host metabolism, transcription and translation. …”

The increased apoptosis and the decreased cell proliferation during development of the cerebral cortex in <i>lag/lag</i> mice. by Kohei Fujikura (106428)

Sensitivity of N2A stable clones to GCV. by Elizabeth Wei-Chia Luo (11250668)

“…<p>(A–L) N2A, N2A-pGFAP-HSVtk, and N2A-pCMV-HSVtk cells were treated separately with 0, 1, 5, or 10 μg/ml of GCV for 5 days, and their live-cell phase images or fluorescent images were captured. …”

Sensitivity of U251 stable clones to GCV. by Elizabeth Wei-Chia Luo (11250668)

“…<p>U251, U251-pCMV-HSVtk, and U251-pGFAP-HSVtk cells were treated with 0, 1, 5, or10 μg/ml of GCV for 5 days. (A–D) Live-cell phase images of U251 parent cells displayed no cytotoxicity up to 10 μg/ml of GCV. …”

PD decreases miR-141 levels and the ERK/NF-κB (p65) signaling pathway. by Chuchu Qiao (8831285)

Table_2_Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications.DOCX by Jingxuan Shan (4711089)

“…We found a highly significant association between the CCND1 rs614367-TT genotype (OR = 5.14; P = 0.004) and TNBC risk, and identified a significant association between the rs614367-T allele and decreased PFS in TNBC. …”

Image_2_Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications.JPEG by Jingxuan Shan (4711089)

“…We found a highly significant association between the CCND1 rs614367-TT genotype (OR = 5.14; P = 0.004) and TNBC risk, and identified a significant association between the rs614367-T allele and decreased PFS in TNBC. …”

Patterns of nestin, GFAP, and βIII-tubulin expression in U251-pCMV-HSVtk cells. by Elizabeth Wei-Chia Luo (11250668)

“…(D–F) Filamentous expression of nestin was observed at day 5, day 7, and after recovery. U251-pCMV-HSVtk cells expressed GFAP strongly at day 0 (G), and then gradually decreased expression during 7 days of GCV treatment (H–K). …”

Data_Sheet_2_Comparative Transcriptional Analysis of Lactobacillus plantarum and Its ccpA-Knockout Mutant Under Galactooligosaccharides and Glucose Conditions.PDF by Chen Chen (6544)

“…In total, 489 genes (16%) were differentially transcribed in the wild-type L. plantarum grown on glucose and GOS and the value is decreased to 7% due to the loss of ccpA. Only 6% genes were differentially expressed when the wild-type and the ccpA mutant were compared on GOS. …”

Agonist-induced currents in both TRPV1- and TRPM8-transfected neurons are decreased after prolonged exposure. by Devon C. Crawford (256278)

“…Similar to (A), menthol was added to the bath recording solution. …”

DataSheet_1_Effect of antiviral and immunomodulatory treatment on a cytokine profile in patients with COVID-19.docx by Diana Martonik (16499649)

“…SARS-CoV-2 infection induced cytokine overexpression in hospitalized patients with COVID-19 as well as lymphopenia, particularly a decrease in CD4+ and CD8+ T cell counts. …”

Inhibition of Hsp90 abolished VEGF-mediated eNOS phosphorylation and decreased NO production and cell viability in BAECs. by Yuanzhuo Chen (802891)

Image_5_AP2/ERF Family Transcription Factors ORA59 and RAP2.3 Interact in the Nucleus and Function Together in Ethylene Responses.pdf by Na Young Kim (704555)

“…Octadecanoid-responsive arabidopsis 59 (ORA59) is an ethylene response factor (ERF) transcription factor and has been suggested to integrate ethylene and jasmonic acid signaling and regulate resistance to necrotrophic pathogens. Here we screened for ORA59 interactors using the yeast two-hybrid system to elucidate the molecular function of ORA59. …”

Image_5_AP2/ERF Family Transcription Factors ORA59 and RAP2.3 Interact in the Nucleus and Function Together in Ethylene Responses.pdf by Na Young Kim (704555)

“…Octadecanoid-responsive arabidopsis 59 (ORA59) is an ethylene response factor (ERF) transcription factor and has been suggested to integrate ethylene and jasmonic acid signaling and regulate resistance to necrotrophic pathogens. Here we screened for ORA59 interactors using the yeast two-hybrid system to elucidate the molecular function of ORA59. …”