Table_1_MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment.pdf by Nannan Song (5491205)

“…Herein, we demonstrated that miR-138-5p treatment decreased the growth of tumor cells and increased the number of tumor-infiltrated DCs. miR-138-5p not only down-regulated the expression of cyclin D3 (CCND3), CCD20, Ki67, and MCM in A549/3LL cells, but also regulated the maturation of DCs in A549-bearing nude mice and the 3LL-bearing C57BL/6 mouse model, and DCs’ capability to enhance T cells to kill tumor cells. …”

Image_1_MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment.pdf by Nannan Song (5491205)

“…Herein, we demonstrated that miR-138-5p treatment decreased the growth of tumor cells and increased the number of tumor-infiltrated DCs. miR-138-5p not only down-regulated the expression of cyclin D3 (CCND3), CCD20, Ki67, and MCM in A549/3LL cells, but also regulated the maturation of DCs in A549-bearing nude mice and the 3LL-bearing C57BL/6 mouse model, and DCs’ capability to enhance T cells to kill tumor cells. …”

Image_1_MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment.pdf by Nannan Song (5491205)

“…Herein, we demonstrated that miR-138-5p treatment decreased the growth of tumor cells and increased the number of tumor-infiltrated DCs. miR-138-5p not only down-regulated the expression of cyclin D3 (CCND3), CCD20, Ki67, and MCM in A549/3LL cells, but also regulated the maturation of DCs in A549-bearing nude mice and the 3LL-bearing C57BL/6 mouse model, and DCs’ capability to enhance T cells to kill tumor cells. …”

Table_1_MicroRNA-138-5p Suppresses Non-small Cell Lung Cancer Cells by Targeting PD-L1/PD-1 to Regulate Tumor Microenvironment.pdf by Nannan Song (5491205)

“…Herein, we demonstrated that miR-138-5p treatment decreased the growth of tumor cells and increased the number of tumor-infiltrated DCs. miR-138-5p not only down-regulated the expression of cyclin D3 (CCND3), CCD20, Ki67, and MCM in A549/3LL cells, but also regulated the maturation of DCs in A549-bearing nude mice and the 3LL-bearing C57BL/6 mouse model, and DCs’ capability to enhance T cells to kill tumor cells. …”

The T120P or M172V mutation on <i>rv2172c</i> confers high level <i>para</i>-aminosalicylic acid resistance in <i>Mycobacterium tuberculosis</i> by Jin-Tian Xu (19171738)

“…The results showed that two mutations (T120P and M172V) on <i>rv2172c</i> could be identified in a certain proportion (6.36%) of PAS-resistant isolates. …”

Speech recognition thresholds (SRTs) by listening condition. by Margaret Cychosz (11475772)

Pineapple production in Costa Rica and globally over the last two decades [40] by M E Fagan (557038)

“…We observed that following the ban, mature forest loss decreased from 2.2% to 1.2% per year, and the proportion of pineapple and other export-oriented cropland derived from mature forest declined from 16.4% to 1.9%. …”

<i>L</i>. <i>major</i> LV39 upregulate c-MET mRNA expression selectively in neutrophils. by Katiuska Passelli (11965496)

The statistical data of the partial graph. by Si Yu Zhao (19544793)

“…</p><p>Methodology/Principal findings</p><p>We blindfolded adult female compound eyes and observed the effects of a lack of vision on the ability to discriminate and utilize preferred oviposition sites. …”

Experimental Design Flowchart. by Si Yu Zhao (19544793)

“…</p><p>Methodology/Principal findings</p><p>We blindfolded adult female compound eyes and observed the effects of a lack of vision on the ability to discriminate and utilize preferred oviposition sites. …”

Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and... by Dilpreet Kour (10872766)

“…Subsequent brain tissue analysis revealed that IBC upregulated autophagic proteins to reduce the brain’s amyloid beta levels, resulting in decreased expression of neuroinflammation markers.</p>Conclusion<p>IBC effectively ameliorates AD pathology through autophagy-mediated clearance of Aβ and suppressing neuroinflammation in 5x-FAD mice.…”

Anti-Diabetic Effects of Jiang Tang Xiao Ke Granule via PI3K/Akt Signalling Pathway in Type 2 Diabetes KKAy Mice by Na Yu (151735)

“…We concluded that JTXK granule is an effective drug for T2DM through regulating the PI3K/Akt signalling pathway in skeletal muscle.…”

HGF levels and PMNs infiltration in the ear of mice 24h after infection with 10⁶ <i>L</i>. <i>mexicana</i>. by Katiuska Passelli (11965496)

Immunofluorescence analysis using dual staining for E-cadherin (E-cad) and afadin and F-actin in RPTECs infected with Oki53 and Oki65 at 24 h post-infection. by Tetsuya Kakita (4922584)

A 60-year-old male with a hyperacute cardioembolic infarction fifteen hours after the onset. by Daichi Momosaka (6160418)

“…<b>G:</b> MTR_asym spectra show decreased MTR_asym (3.5ppm) or APTW signal (%) in the infarct area compared to the CNAWM. mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; FLAIR, fluid attenuated inversion recovery; DWI, diffusion-weighted imaging; ROI, region-of-interest; ADC, apparent diffusion coefficient; APTW, amide proton transfer-weighted; CEST, chemical exchange saturation transfer; CNAWM, contralateral normal-appearing white matter; S_sat(ppm) and S0, the signal intensities obtained with and without selective radiofrequency saturation pulse irradiation, respectively; APT₁₀, APT₂₅, APT₅₀, APT₇₅, and APT₉₀ correspond to the 10th, 25th, 50th, 75th, and 90th percentiles of the APTW signal value within the ROI, respectively.…”

A 59-year-old male with a subacute atherosclerotic infarction nine days after the onset. by Daichi Momosaka (6160418)

“…<b>G:</b> MTR_asym spectra show decreased MTR_asym(3.5ppm) or APTW signal (%) in the infarct area compared to the CNAWM. mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; FLAIR, fluid attenuated inversion recovery; DWI, diffusion-weighted imaging; ROI, region-of-interest; ADC, apparent diffusion coefficient; APTW, amide proton transfer-weighted; CEST, chemical exchange saturation transfer; CNAWM, contralateral normal-appearing white matter; S_sat (ppm) and S₀, the signal intensities obtained with and without selective radiofrequency saturation pulse irradiation, respectively; APT₁₀, APT₂₅, APT₅₀, APT₇₅, and APT₉₀, correspond to the 10th, 25th, 50th, 75th, and 90th percentiles of APTW signal value, respectively.…”

Inulin Supplementation Lowered the Metabolic Defects of Prolonged Exposure to Chlorpyrifos from Gestation to Young Adult Stage in Offspring Rats by Julie Reygner (597566)

“…<div><p>Increasing evidence indicates that chlorpyrifos (CPF), an organophosphorus insecticide, is involved in metabolic disorders. We assess the hypothesis whether supplementation with prebiotics from gestation to adulthood, through a modulation of microbiota composition and fermentative activity, alleviates CPF induced metabolic disorders of 60 days old offspring. 5 groups of Wistar rats, from gestation until weaning, received two doses of CPF pesticide: 1 mg/kg/day (CPF1) or 3.5 mg/kg/day (CPF3.5) with free access to inulin (10g/L in drinking water). …”

The Impact of Policy Guidelines on Hospital Antibiotic Use over a Decade: A Segmented Time Series Analysis by Sujith J. Chandy (302403)

“…Pairwise segmented regression adjusted for seasonality revealed a significant drop in monthly antibiotic use of 0.401 (SE = 0.089; <i>p</i><0.001) for Segment 5 compared to Segment 4. …”

The protective effect of the EP2 receptor on TGF-β1 induced podocyte injury via the PI3K / Akt signaling pathway by Jing Liu (38537)

“…Previous studies have shown that phosphoinositide 3-OH kinase (PI3K)/Akt is widespread in cells, and is vital for the regulation of cell proliferation, differentiation, apoptosis and metabolism. In this study, we cultured immortalized mouse podocytes in vitro in different groups: control group; TGF-β1 (5ng/ml) group; EP2 agonist Butaprost treatment (10⁻⁷, 10⁻⁶, or 10^-5mol/L) +TGF-β1 group; EP2 antagonist AH6809 treatment (10⁻⁷, 10⁻⁶, or 10^-5mol / L) + TGF-β1 group. …”

Discovery of a Novel Class of d‑Amino Acid Oxidase Inhibitors Using the Schrödinger Computational Platform by Haifeng Tang (488592)