A3F translocations on ssDNA are distinct from A3G, but not due to intersegmental transfer. by Anjuman Ara (540372)

“…This was distinct from A3G that was processive when cytosines were closely spaced (5- to 14- nt apart), reached a maximum processivity when cytosines were 30- to 63- nt apart and then decreased in processivity (filled squares). …”

Fibronectin Affects Transient <i>MMP2</i> Gene Expression through DNA Demethylation Changes in Non-Invasive Breast Cancer Cell Lines by Isabela T. Pereira (627901)

“…In this work, we showed that fibronectin was able to induce <i>MMP2</i> expression by 30% decrease in its promoter methylation. …”

Image2_Dragonfly Conservation in the Increasingly Stressed African Mediterranean-Type Ecosystems.pdf by Rassim Khelifa (2867750)

Image 2_ATP/P2X7 receptor signal aggravates ischemic stroke injury by activating Th17 cells via STAT3/IL-21 pathway.tif by Wenying Liu (781302)

“…We also confirmed that P2X7 receptor regulates IL-21 through STAT3 signaling.…”

Data_Sheet_2_The Change of Public Individual Prevention Practice and Psychological Effect From the Early Outbreak Stage to the Controlled Stage of COVID-19 in China in 2020: Two Cr... by Bingfeng Han (5094995)

“…People’s anxiety (STAI score) across the country has decreased from a median of 19 in the early outbreak stage to a median of 12, including people with all demographic characteristics, but some have increased in 16 provinces.…”

Electronic configuration of the polypeptide backbone versus complexity of tertiary structure and order of oligomerization in soluble and integral membrane proteins. by Andrzej Stanisław Cieplak (2717653)

“…For α-helices, narrow distribution of the folding potential values and the slope values, Δ<i>FP</i>_{<i>i-1→i+1</i>} ~0, generates compact clusters of the data points. As the complexity of α structure increases and the exposure to the medium decreases, this clusters shift from <i>FP</i>_<i>i</i> >0 to <i>FP</i>_<i>i</i> <0 region in the case of soluble proteins, see the panels in <b>(A)</b>, and in the opposite direction, from <i>FP</i>_<i>i</i> <0 to <i>FP</i>_<i>i</i> >0 region in the case of integral membrane proteins, see the panels in <b>(B)</b>. …”

Regulation of NKG2D by RKIP: Implications on NK-mediated cytotoxicity and cytokine production by Galal, Youssef

“…Hypothesizing that there may be a biochemical link between the two, we examined the potential cross talks of signaling pathways between NKG2D and RKIP. …”
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Image_1_Twenty-Four Hour Blood Pressure Response to Empagliflozin and Its Determinants in Normotensive Non-diabetic Subjects.JPEG by Anne Zanchi (645982)

“…</p>Results<p>At 1 month, empagliflozin 10 mg decreased 24-h systolic (SBP) and diastolic (DBP) BP significantly by −5 ± 7 mmHg (p < 0.001) and −2 ± 6 mmHg (p = 0.03). …”

Behavioral profile of zebrafish larvae to AEDs. by Tatiana Afrikanova (288839)

“…<p>(A) The top graph depicts the average larval locomotor activity within 30 minutes (y-axis) relative to VHC+PTZ (PTZ) control, as depicted by the average % ± SEM; treatment groups where average movement was significantly decreased compared to PTZ (one-way ANOVA) are marked *, **, and *** (p<0.05, p<0.01, and p<0.001, respectively). …”

Developmentally regulated promoter-switch transcriptionally controls function during embryonic hematopoiesis-2 by Amir Pozner (78042)

“…Following FACS analysis an equal number (1 × 10) of E15.5 WT or P2Annexin V negative thymocytes were incubated with TPA (20 ng/ml) and ConA (5 μg/ml) for 48 h. …”

New ASM splice variants act in a dominant-negative manner. A. Modulation of ceramide:sphingomyelin ratios. by Cosima Rhein (168205)

“…In contrast, the ratio significantly decreased upon overexpression of ASM-5, -6 and -7 (p<0.01 for ASM-6; p<0.05 for ASM-5 and -7). …”

Image_2_The atypical chemokine receptor 2 reduces T cell expansion and tertiary lymphoid tissue but does not limit autoimmune organ injury in lupus-prone B6lpr mice.pdf by Wenkai Xia (670350)

“…</p>Discussion<p>In summary, we show that ACKR2 prevents expansion of T cells and formation of tertiary lymphoid tissue, but is not essential to limit autoimmune tissue injury in lupus-prone B6lpr mice.…”

Peptide amidation in control and <i>nemy</i> mutants. by David Knight (53442)

“…The intensity of amidated neuropeptides was normalized against the intensity of non-amidated peptides in the same sample. We observed an increase in the amidation of neuropeptides in <i>nemy</i>^26.2 mutants, and a decrease in the amidation of neuropeptides in <i>nemy</i>⁴⁵ mutants. …”

Effect of glycosylation on purified TibA. by Jean-Philippe Côté (487399)

“…Right after the denaturation, temperature was decreased from 80°C to 25°C at a rate of 5°C per minute and the ellipticities were recorded at 218 nm for glycosylated TibA (gray) and unglycosylated TibA (orange).…”

DataSheet_1_miR-186-ANXA9 signaling inhibits tumorigenesis in breast cancer.pdf by Zhongrui Wang (6315929)

“…In addition, miR-186-5p decreased the expression of Bcl-2 and increased the expression of p53, suggesting a mechanism regulating miR-186-5p-induced cellular apoptosis. …”

Copepod assemblage structure (Crustacea: Copepoda) along a longitudinal environmental gradient in a tropical river-floodplain system, Brazil by Welinton Sousa Palhiarini (4701463)

“…Sampling sites were located along the Paraná River, in seven of its tributaries, and in eight lakes located in its floodplain. Results We identified 29 species belonging to two families: Cyclopidae (21 species) and Diaptomidae (eight species). …”

RSV A2 replication in the ovine model. by Thomas Démoulins (517537)

“…After the initial decrease of RSV A2 titers, a second peak was detected in 5 out of 6 animals, showing the capacity of RSV A2 to replicate <i>in vivo</i> in the ovine model.…”

Table_1_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla... by Chenhaoyi Xu (12456795)

“…Knockdown of METTL3 decreased ARC mRNA m⁶A modification and reduced ARC protein expression, while overexpression of METTL3 rescued ARC expression after Aβ treatment. …”

Image_1_Methyltransferase-Like 3 Rescues the Amyloid-beta protein-Induced Reduction of Activity-Regulated Cytoskeleton Associated Protein Expression via YTHDF1-Dependent N6-Methyla... by Chenhaoyi Xu (12456795)

“…Knockdown of METTL3 decreased ARC mRNA m⁶A modification and reduced ARC protein expression, while overexpression of METTL3 rescued ARC expression after Aβ treatment. …”

Effect of B and W input correlations on the balance of D1 and D2 activity. by Jyotika Bahuguna (729510)

“…Here, we considered the scenario-II and set <i>J</i>_<i>C</i>1 = 3.6 nS, <i>J</i>_<i>C</i>2 = 3.0 nS. …”